PMID- 34115242 OWN - NLM STAT- MEDLINE DCOM- 20210624 LR - 20210625 IS - 1534-6285 (Electronic) IS - 1527-2737 (Linking) VI - 22 IP - 8 DP - 2021 Jun 11 TI - How I Handle Retreatment of LUTS Following a Failed MIST. PG - 40 LID - 10.1007/s11934-021-01054-w [doi] AB - PURPOSE OF REVIEW: The goal of this paper is to review retreatment management after failed minimally invasive treatment (MIST) of various technologies. RECENT FINDINGS: A failed MIST can be defined by the return, persistence, or worsening of LUTS, as documented by symptom scores. Persistence, development, or recurrence of comorbidities such as recurrent urinary tract infection (UTI), retention, stones, hematuria, and incontinence can also signal a failed MIST. The common etiology for MIST failure is the preoperative consequence of long-term bladder outlet obstruction (BOO) on the bladder function. Close monitoring of therapies with antimuscarinics or beta-agonists can be empirically utilized if post-void bladder residual (PVR) is low. If there is a high PVR, urodynamic studies and cystoscopy can be used to determine overactive bladder (OAB), BOO, or necrosis. Depending on the timing of the observed BOO/OAB, subsequent retreatments involving transurethral debridement, medical and behavioral therapies, or repeat surgical debulking can be employed. FAU - Te, Alexis E AU - Te AE AUID- ORCID: 0000-0002-5815-7196 AD - Department of Urology, Weill Cornell Medical College of Cornell University, 425 East 61st street, 12th floor, New York, NY, 10065, USA. aet2005@med.cornell.edu. FAU - Cho, Ahra AU - Cho A AD - Department of Urology, Weill Cornell Medical College of Cornell University, 425 East 61st street, 12th floor, New York, NY, 10065, USA. FAU - Chughtai, Bilal I AU - Chughtai BI AD - Department of Urology, Weill Cornell Medical College of Cornell University, 425 East 61st street, 12th floor, New York, NY, 10065, USA. LA - eng PT - Journal Article PT - Review DEP - 20210611 PL - United States TA - Curr Urol Rep JT - Current urology reports JID - 100900943 SB - IM MH - Cytoreduction Surgical Procedures MH - Humans MH - *Minimally Invasive Surgical Procedures MH - Recurrence MH - *Retreatment MH - Treatment Failure MH - Urinary Tract Infections/*surgery OTO - NOTNLM OT - Complications OT - Failed minimally invasive surgical treatment OT - Limitations OT - Re-treatments EDAT- 2021/06/12 06:00 MHDA- 2021/06/25 06:00 CRDT- 2021/06/11 12:25 PHST- 2021/05/22 00:00 [accepted] PHST- 2021/06/11 12:25 [entrez] PHST- 2021/06/12 06:00 [pubmed] PHST- 2021/06/25 06:00 [medline] AID - 10.1007/s11934-021-01054-w [pii] AID - 10.1007/s11934-021-01054-w [doi] PST - epublish SO - Curr Urol Rep. 2021 Jun 11;22(8):40. doi: 10.1007/s11934-021-01054-w.