PMID- 34115296
OWN - NLM
STAT- MEDLINE
DCOM- 20211026
LR  - 20211026
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 28
IP  - 41
DP  - 2021 Nov
TI  - Particulate matter pollution associated with schizophrenia hospital 
      re-admissions: a time-series study in a coastal Chinese city.
PG  - 58355-58363
LID - 10.1007/s11356-021-14816-3 [doi]
AB  - Schizophrenia (SCZ) hospital re-admissions constitute a serious disease burden 
      worldwide. Some studies have reported an association between air pollutants and 
      hospital admissions for SCZ. However, evidence is scarce regarding the effects of 
      ambient particulate matter (PM) on SCZ hospital re-admissions, especially in 
      coastal cities in China. The purpose of this study was to examine whether PM 
      affects the risk of SCZ hospital re-admission in the coastal Chinese city of 
      Qingdao. Daily SCZ hospital re-admissions, daily air pollutants, and 
      meteorological factors from 2015 to 2019 were collected. A quasi-Poisson 
      generalized linear regression model combined with distributed lag non-linear 
      model (DLNM) was applied to model the exposure-lag-response relationship between 
      PM and SCZ hospital re-admissions. The relative risks (RRs) were estimated for an 
      inter-quartile range (IQR) increase in PM concentrations. Subgroup analyses by 
      age and gender were conducted to identify the vulnerable subgroups. There were 
      6220 SCZ hospital re-admissions during 2015-2019. The results revealed that PM, 
      including PM(10) (particles with an aerodynamic diameter </=10 mum), PM(c) 
      (particles >2.5 mum but <10 mum), and PM(2.5) (particles </=2.5 mum), was positively 
      correlated with SCZ hospital re-admissions. The strongest single-day effects all 
      occurred on lag3 day, and the corresponding RRs were 1.07 (95% CI: 1.02-1.11) for 
      PM(10), 1.03 (95% CI: 1.00-1.07) for PM(c), and 1.05 (95% CI: 1.01-1.09) for 
      PM(2.5) per IQR increase. Stronger associations were observed in males and 
      younger individuals (<45 years). Our findings suggest that PM exposure is 
      associated with increased risk of SCZ hospital re-admission. Active intervention 
      measures against PM exposure should be taken to reduce the risk of SCZ hospital 
      re-admission, especially for males and younger individuals.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, 
      part of Springer Nature.
FAU - Ji, Yanhu
AU  - Ji Y
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Anhui 
      Medical University, 81 Meishan Road, Hefei, Anhui, China.
FAU - Liu, Bin
AU  - Liu B
AD  - Qingdao Mental Health Center, Qingdao, Shandong, China.
FAU - Song, Jian
AU  - Song J
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Anhui 
      Medical University, 81 Meishan Road, Hefei, Anhui, China.
FAU - Pan, Rubing
AU  - Pan R
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Anhui 
      Medical University, 81 Meishan Road, Hefei, Anhui, China.
FAU - Cheng, Jian
AU  - Cheng J
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Anhui 
      Medical University, 81 Meishan Road, Hefei, Anhui, China.
FAU - Su, Hong
AU  - Su H
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Anhui 
      Medical University, 81 Meishan Road, Hefei, Anhui, China.
FAU - Wang, Heng
AU  - Wang H
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Anhui 
      Medical University, 81 Meishan Road, Hefei, Anhui, China. wangheng1969@163.com.
AD  - The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, 
      Anhui Province, China. wangheng1969@163.com.
LA  - eng
GR  - 71774001/National Natural Science Foundation of China/
PT  - Journal Article
DEP - 20210611
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Air Pollutants)
RN  - 0 (Particulate Matter)
SB  - IM
MH  - *Air Pollutants/analysis
MH  - *Air Pollution/analysis
MH  - China
MH  - Cities
MH  - Environmental Exposure
MH  - Hospitalization
MH  - Hospitals
MH  - Humans
MH  - Male
MH  - Particulate Matter/analysis
MH  - *Schizophrenia/epidemiology
OTO - NOTNLM
OT  - Air pollution
OT  - DLNM
OT  - Hospital re-admission
OT  - Particulate matter
OT  - Schizophrenia
EDAT- 2021/06/12 06:00
MHDA- 2021/10/27 06:00
CRDT- 2021/06/11 12:26
PHST- 2021/03/08 00:00 [received]
PHST- 2021/06/07 00:00 [accepted]
PHST- 2021/06/12 06:00 [pubmed]
PHST- 2021/10/27 06:00 [medline]
PHST- 2021/06/11 12:26 [entrez]
AID - 10.1007/s11356-021-14816-3 [pii]
AID - 10.1007/s11356-021-14816-3 [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2021 Nov;28(41):58355-58363. doi: 
      10.1007/s11356-021-14816-3. Epub 2021 Jun 11.