PMID- 34119853
OWN - NLM
STAT- MEDLINE
DCOM- 20211025
LR  - 20211025
IS  - 1618-131X (Electronic)
IS  - 1438-4639 (Linking)
VI  - 236
DP  - 2021 Jul
TI  - First nationwide exposure profile of major persistent organic pollutants among 
      Korean adults and their determinants: Korean National Environmental Health Survey 
      Cycle 3 (2015-2017).
PG  - 113779
LID - S1438-4639(21)00094-8 [pii]
LID - 10.1016/j.ijheh.2021.113779 [doi]
AB  - Since 2009, Korea has measured the exposure levels of major environmental 
      chemicals and heavy metals among representative adult populations through the 
      Korean National Environmental Health Survey (KoNEHS). However, exposure to 
      persistent organic pollutants (POPs) has never been assessed. This study reports 
      the serum concentrations of twenty-four POPs and their influencing factors for 
      Korean adults (n = 1295) who participated in the KoNEHS Cycle 3 (2015-2017). The 
      POPs included seven organochlorine pesticides (OCPs), eleven polychlorinated 
      biphenyls (PCBs), and six polybrominated diphenyl ethers (PBDEs). Among them, 
      three OCPs (i.e., hexachlorobenzene (HCB), p,p'-dichlorodiphenyltrichloroethane 
      (p,p'-DDT), and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE)) and five PCBs 
      (i.e., PCB52, PCB118, PCB138, PCB153, and PCB180) were detected in over 60% of 
      the samples. PBDEs were not detected at a detection frequency of 60% or above. 
      The most frequently detected POPs were p,p'-DDE (99.8%, geometric mean of 
      128.47 ng/g lipid), followed by PCB180 (98.8%, 8.49 ng/g lipid), PCB153 (98.8%, 
      13.14 ng/g lipid), HCB (96.2%, 67.08 ng/g lipid), PCB138 (95.2%, 8.84 ng/g 
      lipid), PCB118 (89.6%, 2.66 ng/g lipid), p,p'-DDT (80.5%, 6.68 ng/g lipid), and 
      PCB52 (71.2%, 1.57 ng/g lipid). The concentrations of most POPs were lower than 
      or similar to concentrations reported in national-scale biomonitoring surveys. 
      The only exception was HCB, whose concentration was up to seven-fold higher than 
      the concentration reported by the Canadian Health Measures Survey. Excluding HCB 
      and PCB52, most POPs showed increasing serum levels among older adults, adults 
      with higher body mass index, adults living in coastal areas, and more frequent 
      fish consumption. Relatively higher POP concentrations were observed in 
      menopausal women. This study provides the first data on POP exposure levels among 
      the representative adult population in Korea, and the results highlight the need 
      to integrate POPs in the national biomonitoring program.
CI  - Copyright (c) 2021 Elsevier GmbH. All rights reserved.
FAU - Jeon, Hye Li
AU  - Jeon HL
AD  - Environmental Health Research Division, National Institute of Environmental 
      Research, Ministry of Environment, Incheon, Republic of Korea.
FAU - Hong, Sooyeon
AU  - Hong S
AD  - Environmental Health Research Division, National Institute of Environmental 
      Research, Ministry of Environment, Incheon, Republic of Korea.
FAU - Choi, Kyungho
AU  - Choi K
AD  - Graduate School of Public Health, Seoul National University, Seoul, Republic of 
      Korea.
FAU - Lee, Chulwoo
AU  - Lee C
AD  - Environmental Health Research Division, National Institute of Environmental 
      Research, Ministry of Environment, Incheon, Republic of Korea.
FAU - Yoo, Jiyoung
AU  - Yoo J
AD  - Environmental Health Research Division, National Institute of Environmental 
      Research, Ministry of Environment, Incheon, Republic of Korea. Electronic 
      address: yjy0216@korea.kr.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210610
PL  - Germany
TA  - Int J Hyg Environ Health
JT  - International journal of hygiene and environmental health
JID - 100898843
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Aged
MH  - Animals
MH  - Canada
MH  - Environmental Health
MH  - Environmental Monitoring
MH  - *Environmental Pollutants/analysis
MH  - Female
MH  - Humans
MH  - *Hydrocarbons, Chlorinated/analysis
MH  - Persistent Organic Pollutants
MH  - *Pesticides/analysis
MH  - *Polychlorinated Biphenyls/analysis
MH  - Republic of Korea
OTO - NOTNLM
OT  - Bioaccumulation
OT  - Biomonitoring
OT  - Exposure
OT  - KoNEHS cycle 3
OT  - POPs
EDAT- 2021/06/14 06:00
MHDA- 2021/10/26 06:00
CRDT- 2021/06/13 20:48
PHST- 2021/01/08 00:00 [received]
PHST- 2021/04/21 00:00 [revised]
PHST- 2021/05/27 00:00 [accepted]
PHST- 2021/06/14 06:00 [pubmed]
PHST- 2021/10/26 06:00 [medline]
PHST- 2021/06/13 20:48 [entrez]
AID - S1438-4639(21)00094-8 [pii]
AID - 10.1016/j.ijheh.2021.113779 [doi]
PST - ppublish
SO  - Int J Hyg Environ Health. 2021 Jul;236:113779. doi: 10.1016/j.ijheh.2021.113779. 
      Epub 2021 Jun 10.