PMID- 34123658
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231111
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 13
IP  - 5
DP  - 2021 May 11
TI  - Kawasaki Disease Shock Syndrome in the Eastern Region of Saudi Arabia: Case 
      Series.
PG  - e14961
LID - 10.7759/cureus.14961 [doi]
LID - e14961
AB  - Kawasaki disease (KD) is a treatable medium-sized vasculitis in the pediatric 
      population consisting of a myriad of specific signs and symptoms. A new entity of 
      the disease, Kawasaki disease shock syndrome (KDSS), is defined as a KD patient 
      presenting with signs of hypoperfusion. Our aim is to describe the signs and 
      symptoms of KDSS and how it is treated and its consequences. Out of 37 patients 
      diagnosed with KD in the period between January 2018 and December 2019 in 
      hospitalized patients younger than 14 years of age at Maternity and Children's 
      Hospital in Al-Hassa, Eastern Province, Saudi Arabia, 3 (8.10%) patients 
      fulfilled the diagnostic criteria for KDSS: 2 (66%) were male and 1 (33%) was 
      female. The cardinal feature in all of them was peripheral cardiovascular 
      collapse. Two patients (66%) were found to have aseptic meningitis. All patients 
      were treated with immunomodulatory agents (intravenous immunoglobulin) and all 
      responded well to anti-inflammatory doses of aspirin. KDSS is the shock state of 
      KD presenting with hypoperfusion symptoms, mainly irritability and changes in the 
      level of consciousness and peripheral cardiovascular collapse. Awareness of such 
      presentation and management by immunomodulatory medications helps in recovery and 
      prevention of tragic consequences of such disease.
CI  - Copyright (c) 2021, Busaleh et al.
FAU - Busaleh, Fadi
AU  - Busaleh F
AD  - Pediatrics, Maternity and Children Hospital, Al-Ahsa, SAU.
FAU - AlKadhem, Sajjad M
AU  - AlKadhem SM
AD  - Pediatrics, Maternity and Children Hospital, Al-Ahsa, SAU.
FAU - Albarrak, Aymen
AU  - Albarrak A
AD  - Pediatrics, Maternity and Children Hospital, Al-Ahsa, SAU.
FAU - Almubarak, Abdullah A
AU  - Almubarak AA
AD  - College of Medicine, King Faisal University, Al-Ahsa, SAU.
FAU - Aldandan, Mahmoud M
AU  - Aldandan MM
AD  - Collage of Medicine, King Faisal University, Al-Ahsa, SAU.
FAU - Almajed, Jumanah M
AU  - Almajed JM
AD  - College of Medicine, King Faisal University, Al-Ahsa, SAU.
FAU - Alabdullah, Mujtaba A
AU  - Alabdullah MA
AD  - College of Medicine, King Faisal University, Al-Ahsa, SAU.
FAU - Almulaifi, Luay F
AU  - Almulaifi LF
AD  - College of Medicine, King Faisal University, Al-Ahsa, SAU.
LA  - eng
PT  - Case Reports
DEP - 20210511
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC8191643
OTO - NOTNLM
OT  - incomplete kawasaki disease
OT  - kawasaki disease
OT  - kawasaki disease shock syndromes
OT  - multi-system inflammatory disease in children (mis-c)
OT  - shock
COIS- The authors have declared that no competing interests exist.
EDAT- 2021/06/15 06:00
MHDA- 2021/06/15 06:01
PMCR- 2021/05/11
CRDT- 2021/06/14 09:47
PHST- 2021/06/14 09:47 [entrez]
PHST- 2021/06/15 06:00 [pubmed]
PHST- 2021/06/15 06:01 [medline]
PHST- 2021/05/11 00:00 [pmc-release]
AID - 10.7759/cureus.14961 [doi]
PST - epublish
SO  - Cureus. 2021 May 11;13(5):e14961. doi: 10.7759/cureus.14961.