PMID- 34124994
OWN - NLM
STAT- MEDLINE
DCOM- 20211125
LR  - 20220425
IS  - 2168-1813 (Electronic)
IS  - 2168-1805 (Linking)
VI  - 55
IP  - 4
DP  - 2021 Aug
TI  - Survival after radical cystectomy during holiday periods.
PG  - 276-280
LID - 10.1080/21681805.2021.1938665 [doi]
AB  - OBJECTIVE: For patients undergoing radical cystectomy for bladder cancer, a 
      procedure requiring complex urinary tract reconstruction prone to major 
      postoperative complications, the timing and quality of the surgery have been 
      associated with outcomes. PATIENTS AND METHODS: This study investigated if 
      radical cystectomy for bladder cancer performed during holiday periods had worse 
      disease-specific (DSS) and overall survival (OS), higher 90-day mortality and 
      risk of readmissions. All patients operated on with radical cystectomy for 
      primary bladder cancer during 1997-2014 with holiday periods as exposure (with 
      one narrow (7 weeks) and one wider (14 weeks) definition) in the Swedish 
      population-based bladder cancer research-database (BladderBaSe) were studied. DSS 
      and OS after radical cystectomy during holiday periods were analysed with Cox 
      regression models adjusted for sex, age, comorbidity, marital status, T-stage and 
      nodal metastases, neoadjuvant chemotherapy, hospital volume and year of 
      cystectomy. RESULTS: Surgery during the holiday periods (narrow and wide 
      definitions) were not associated with DSS (Hazard ratio [HR] = 1.05, 95% 
      confidence interval [95% CI] = 0.90-1.21 and HR = 1.04, 95% CI = 0.91-1.17), 
      respectively. HRs for OS were similar, and no associations between radical 
      cystectomy during any of the holiday period definitions and 90-day mortality and 
      readmission were found. CONCLUSION: Survival after radical cystectomy in Sweden 
      is similar during holiday and non-holiday periods.
FAU - Liedberg, Fredrik
AU  - Liedberg F
AUID- ORCID: 0000-0001-8193-0370
AD  - Department of Urology, Skane University Hospital, Malmo, Sweden.
AD  - Institution of Translational Medicine, Lund University, Malmo, Sweden.
FAU - Hagberg, Oskar
AU  - Hagberg O
AD  - Institution of Translational Medicine, Lund University, Malmo, Sweden.
AD  - Regional Cancer Centre South, Region Skane, Lund, Sweden.
FAU - Aljabery, Firas
AU  - Aljabery F
AD  - Department of Clinical and Experimental Medicine, Division of Urology, Linkoping 
      University, Linkoping, Sweden.
FAU - Gardmark, Truls
AU  - Gardmark T
AD  - Department of Clinical Sciences, Danderyd Hospital, Karolinska Institute, 
      Stockholm, Sweden.
FAU - Hosseini, Abolfazl
AU  - Hosseini A
AD  - Department of Molecular Medicine and Surgery, Karolinska Institute and Department 
      of Pelvic Cancer, Karolinska University Hospital, Stockholm, Sweden.
FAU - Jahnson, Staffan
AU  - Jahnson S
AD  - Department of Clinical and Experimental Medicine, Division of Urology, Linkoping 
      University, Linkoping, Sweden.
FAU - Jerlstrom, Tomas
AU  - Jerlstrom T
AD  - Department of Urology, School of Medical Sciences, Faculty of Medicine and 
      Health, Orebro University, Orebro, Sweden.
FAU - Malmstrom, Per-Uno
AU  - Malmstrom PU
AD  - Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
FAU - Sherif, Amir
AU  - Sherif A
AD  - Department of Surgical and Perioperative Sciences, Urology and Andrology, Umea 
      University, Umea, Sweden.
FAU - Soderkvist, Karin
AU  - Soderkvist K
AD  - Department of Radiation Sciences, Umea University, Umea, Sweden.
FAU - Strock, Viveka
AU  - Strock V
AD  - Department of Urology, Sahlgrenska University Hospital and Institute of Clinical 
      Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden.
FAU - Ullen, Anders
AU  - Ullen A
AD  - Department of Oncology-Pathology, Karolinska Institute, and Department of Pelvic 
      Cancer, Karolinska University Hospital, Stockholm, Sweden.
FAU - Haggstrom, Christel
AU  - Haggstrom C
AD  - Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
AD  - Department of Public health and Clinical Medicine, Umea University, Sweden.
FAU - Holmberg, Lars
AU  - Holmberg L
AD  - Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
AD  - School of Cancer and Pharmaceutical Sciences, King's College London, London, UK.
LA  - eng
PT  - Journal Article
DEP - 20210614
PL  - Sweden
TA  - Scand J Urol
JT  - Scandinavian journal of urology
JID - 101587186
SB  - IM
MH  - *Cystectomy
MH  - Holidays
MH  - Humans
MH  - Proportional Hazards Models
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - *Urinary Bladder Neoplasms/surgery
OTO - NOTNLM
OT  - Bladder cancer
OT  - holiday periods
OT  - radical cystectomy
OT  - survival
EDAT- 2021/06/15 06:00
MHDA- 2021/11/26 06:00
CRDT- 2021/06/14 12:23
PHST- 2021/06/15 06:00 [pubmed]
PHST- 2021/11/26 06:00 [medline]
PHST- 2021/06/14 12:23 [entrez]
AID - 10.1080/21681805.2021.1938665 [doi]
PST - ppublish
SO  - Scand J Urol. 2021 Aug;55(4):276-280. doi: 10.1080/21681805.2021.1938665. Epub 
      2021 Jun 14.