PMID- 34125075 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20211120 IS - 1929-0748 (Print) IS - 1929-0748 (Electronic) IS - 1929-0748 (Linking) VI - 10 IP - 6 DP - 2021 Jun 14 TI - Motivation and Problem Solving Versus Mobile 360 degrees Videos to Promote Enrollment in the National Diabetes Prevention Program's Lifestyle Change Program Among People With Prediabetes: Protocol for a Randomized Trial. PG - e28884 LID - 10.2196/28884 [doi] LID - e28884 AB - BACKGROUND: More than 88 million Americans are at risk of developing type 2 diabetes mellitus (T2DM). The National Diabetes Prevention Program's Lifestyle Change Program (DPP LCP) has been shown to be effective in reducing the risk of progressing from prediabetes to T2DM. However, most individuals who could benefit from the program do not enroll. OBJECTIVE: The aim of this trial is to test the real-world efficacy of 3 mobile phone-based approaches to increasing enrollment in the DPP LCP including a best-practice condition and 2 novel approaches. METHODS: We will conduct a 3-armed randomized clinical trial comparing enrollment and 1-month engagement in the DPP LCP among adults with prediabetes from 2 health care settings. Participants in the best-practice condition will receive SMS-based notifications that they have prediabetes and a link to a website that explains prediabetes, T2DM, and the DPP LCP. This will be followed by a single question survey, "Would you like the DPP LCP to call you to enroll?" Participants in the 2 intervention arms will receive the same best-practice intervention plus either 2 mobile 360 degrees videos or up to 5 brief phone calls from a health coach trained in a motivational coaching approach known as Motivation and Problem Solving (MAPS). We will collect measures of diabetes-related knowledge, beliefs in the controllability of risk for T2DM, risk perceptions for T2DM, and self-efficacy for lifestyle change pre-intervention and 4 weeks later. The primary outcomes of the study are enrollment in the DPP LCP and 4-week engagement in the DPP LCP. In addition, data on the person-hours needed to deliver the interventions as well as participant feedback about the interventions and their acceptability will be collected. Our primary hypotheses are that the 2 novel interventions will lead to higher enrollment and engagement in the DPP LCP than the best-practice intervention. Secondary hypotheses concern the mechanisms of action of the 2 intervention arms: (1) whether changes in risk perception are associated with program enrollment among participants in the mobile 360 degrees video group and (2) whether changes in self-efficacy for lifestyle change are associated with program enrollment among participants in the MAPS coaching group. Finally, exploratory analyses will examine the cost effectiveness and acceptability of the interventions. RESULTS: The project was funded in September 2020; enrollment began in February 2021 and is expected to continue through July 2022. CONCLUSIONS: We are conducting a test of 2 novel, scalable, mobile phone-based interventions to increase enrollment in the DPP LCP. If effective, they have tremendous potential to be scaled up to help prevent T2DM nationwide. TRIAL REGISTRATION: ClinicalTrials.gov NCT04746781; https://clinicaltrials.gov/ct2/show/NCT04746781. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/28884. CI - (c)Bryan Gibson, Sara Simonsen, Jonathan Barton, Yue Zhang, Roger Altizer, Kelly Lundberg, David W Wetter. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 14.06.2021. FAU - Gibson, Bryan AU - Gibson B AUID- ORCID: 0000-0003-4747-6383 AD - Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, United States. FAU - Simonsen, Sara AU - Simonsen S AUID- ORCID: 0000-0003-0681-7671 AD - College of Nursing, University of Utah, Salt Lake City, UT, United States. FAU - Barton, Jonathan AU - Barton J AUID- ORCID: 0000-0001-8924-8691 AD - Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, United States. FAU - Zhang, Yue AU - Zhang Y AUID- ORCID: 0000-0002-4124-4816 AD - Division of Epidemiology, University of Utah, Salt Lake City, UT, United States. FAU - Altizer, Roger AU - Altizer R AUID- ORCID: 0000-0003-1048-1912 AD - Entertainment Arts and Engineering, University of Utah, Salt Lake City, UT, United States. FAU - Lundberg, Kelly AU - Lundberg K AUID- ORCID: 0000-0002-1032-5680 AD - Department of Psychiatry, University of Utah, Salt Lake City, UT, United States. FAU - Wetter, David W AU - Wetter DW AUID- ORCID: 0000-0002-4013-1932 AD - Center for Health Outcomes and Population Equity, Huntsman Cancer Institute, Salt Lake City, UT, United States. LA - eng SI - ClinicalTrials.gov/NCT04746781 GR - UL1 TR001067/TR/NCATS NIH HHS/United States PT - Journal Article DEP - 20210614 PL - Canada TA - JMIR Res Protoc JT - JMIR research protocols JID - 101599504 PMC - PMC8240802 OTO - NOTNLM OT - diabetes prevention program OT - mobile video OT - motivation and problem solving OT - participant engagement OT - prediabetes OT - program enrollment COIS- Conflicts of Interest: None declared. EDAT- 2021/06/15 06:00 MHDA- 2021/06/15 06:01 PMCR- 2021/06/14 CRDT- 2021/06/14 12:25 PHST- 2021/03/17 00:00 [received] PHST- 2021/04/28 00:00 [accepted] PHST- 2021/04/22 00:00 [revised] PHST- 2021/06/14 12:25 [entrez] PHST- 2021/06/15 06:00 [pubmed] PHST- 2021/06/15 06:01 [medline] PHST- 2021/06/14 00:00 [pmc-release] AID - v10i6e28884 [pii] AID - 10.2196/28884 [doi] PST - epublish SO - JMIR Res Protoc. 2021 Jun 14;10(6):e28884. doi: 10.2196/28884.