PMID- 34125923 OWN - NLM STAT- MEDLINE DCOM- 20210621 LR - 20231004 IS - 1897-4279 (Electronic) IS - 0022-9032 (Linking) VI - 79 IP - 5 DP - 2021 TI - Cost-effectiveness of telerehabilitation in patients with heart failure in Poland: an analysis based on the results of Telerehabilitation in the Heart Failure Patients (TELEREH-HF) randomized clinical trial. PG - 510-516 LID - 10.33963/KP.15885 [doi] AB - BACKGROUND: Telerehabilitation in the Heart Failure Patients (TELEREH-HF) study showed a statistically significant improvement in the tertiary outcomes i.e. the New York Heart Association (NYHA) class after a 9-week follow-up, consistent with telerehabilitation-related benefits to quality of life (QoL) measured with the 36-item Short Form questionnaire (SF-36). AIMS: The study analyzed the cost-effectiveness of hybrid telerehabilitation compared to standard care in heart failure patients in the Polish setting using findings from the TELEREH-HF trial. METHODS: Cost-utility analysis was conducted from the perspective of a public payer (the Polish National Health Fund). The quality-adjusted life-year (QALY) measure was based on QoL, as survival benefit was not confirmed in the TELEREH-HF. Utility values were estimated based on NYHA improvement and a systematic review of NYHA-specific utility values. Alternatively, SF-36 results were translated into utility values. Telerehabilitation costs covered 8 weeks, 5 days/week, at a daily cost of 74 Polish zloty (PLN). Standard care costs resulted from extra in-patient and out-patient rehabilitation costs incurred for selected patients. A lifetime horizon was adopted, with an estimated average survival time of 3.9 years based on 2 years TELEREH-HF follow-up and subsequent literature-derived prognosis. RESULTS: Base case analysis yielded a 0.044 and 0.027 gain in QALY for the NYHA and SF-36-based approaches, corresponding to a cost per QALY of 58.7 and 96 thousand PLN, respectively. Sensitivity analysis confirmed that the cost per QALY value was likely below the official cost-effectiveness threshold in Poland. CONCLUSIONS: The use of telerehabilitation was found cost-effective in Poland, i.e., the clinical benefits justify the additional costs. FAU - Niewada, Maciej AU - Niewada M AD - Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Warszawa, Poland. AD - HealthQuest, Warszawa, Poland. FAU - Tabor, Bernadetta AU - Tabor B AD - HealthQuest, Warszawa, Poland. FAU - Piotrowicz, Ewa AU - Piotrowicz E AD - Telecardiology Center, National Institute of Cardiology, Warszawa, Poland. epiotrowicz@ikard.pl. FAU - Piotrowicz, Ryszard AU - Piotrowicz R AD - National Institute of Cardiology, Warszawa, Poland. AD - Warsaw Academy of Medicine Rehabilitation, Warszawa, Poland. FAU - Opolski, Grzegorz AU - Opolski G AD - 1st Department of Cardiology, Medical University of Warsaw, Warszawa, Poland. FAU - Banach, Maciej AU - Banach M AD - Department of Hypertension, Medical University of Lodz, Lodz, Poland. FAU - Jakubczyk, Michal AU - Jakubczyk M AD - HealthQuest, Warszawa, Poland. AD - SGH Warsaw School of Economics, Warszawa, Poland. LA - eng PT - Journal Article PL - Poland TA - Kardiol Pol JT - Kardiologia polska JID - 0376352 SB - IM CIN - Kardiol Pol. 2021;79(5):489-490. PMID: 34125919 MH - Cost-Benefit Analysis MH - *Heart Failure MH - Humans MH - Poland MH - Quality of Life MH - Quality-Adjusted Life Years MH - Randomized Controlled Trials as Topic MH - *Telerehabilitation OTO - NOTNLM OT - cost-effectiveness OT - heart failure OT - telerehabilitation EDAT- 2021/06/15 06:00 MHDA- 2021/06/22 06:00 CRDT- 2021/06/14 17:30 PHST- 2021/06/08 00:00 [received] PHST- 2021/06/08 00:00 [accepted] PHST- 2021/06/14 17:30 [entrez] PHST- 2021/06/15 06:00 [pubmed] PHST- 2021/06/22 06:00 [medline] AID - VM/OJS/J/84083 [pii] AID - 10.33963/KP.15885 [doi] PST - ppublish SO - Kardiol Pol. 2021;79(5):510-516. doi: 10.33963/KP.15885.