PMID- 34129248
OWN - NLM
STAT- MEDLINE
DCOM- 20211207
LR  - 20211214
IS  - 1365-3040 (Electronic)
IS  - 0140-7791 (Linking)
VI  - 44
IP  - 9
DP  - 2021 Sep
TI  - Long-term abscisic acid promotes golden2-like1 degradation through constitutive 
      photomorphogenic 1 in a light intensity-dependent manner to suppress chloroplast 
      development.
PG  - 3034-3048
LID - 10.1111/pce.14130 [doi]
AB  - Abiotic stress, a serious threat to plants, occurs for extended periods in 
      nature. Abscisic acid (ABA) plays a critical role in abiotic stress responses in 
      plants. Therefore, stress responses mediated by ABA have been studied 
      extensively, especially in short-term responses. However, long-term stress 
      responses mediated by ABA remain largely unknown. To elucidate the mechanism by 
      which plants respond to prolonged abiotic stress, we used long-term ABA treatment 
      that activates the signalling against abiotic stress such as dehydration and 
      investigated mechanisms underlying the responses. Long-term ABA treatment 
      activates constitutive photomorphogenic 1 (COP1). Active COP1 mediates the 
      ubiquitination of golden2-like1 (GLK1) for degradation, contributing to lowering 
      expression of photosynthesis-associated genes such as glutamyl-tRNA reductase 
      (HEMA1) and protochlorophyllide oxidoreductase A (PORA), resulting in the 
      suppression of chloroplast development. Moreover, COP1 activation and GLK1 
      degradation upon long-term ABA treatment depend on light intensity. Additionally, 
      plants with COP1 mutation or exposed to higher light intensity were more 
      sensitive to salt stress. Collectively, our results demonstrate that long-term 
      treatment of ABA leads to activation of COP1 in a light intensity-dependent 
      manner for GLK1 degradation to suppress chloroplast development, which we propose 
      to constitute a mechanism of balancing normal growth and stress responses upon 
      the long-term abiotic stress.
CI  - (c) 2021 John Wiley & Sons Ltd.
FAU - Lee, Juhun
AU  - Lee J
AD  - Division of Integrative Biosciences and Biotechnology, Pohang University of 
      Science and Technology, Pohang, South Korea.
FAU - Choi, Bongsoo
AU  - Choi B
AD  - Division of Integrative Biosciences and Biotechnology, Pohang University of 
      Science and Technology, Pohang, South Korea.
FAU - Yun, Areum
AU  - Yun A
AD  - Division of Integrative Biosciences and Biotechnology, Pohang University of 
      Science and Technology, Pohang, South Korea.
FAU - Son, Namil
AU  - Son N
AD  - Division of Integrative Biosciences and Biotechnology, Pohang University of 
      Science and Technology, Pohang, South Korea.
FAU - Ahn, Gyeongik
AU  - Ahn G
AD  - Division of Applied Life Science (BK21Plus), RILS & IALS, Gyeongsang National 
      University, Jinju, Republic of Korea.
FAU - Cha, Joon-Yung
AU  - Cha JY
AD  - Division of Applied Life Science (BK21Plus), RILS & IALS, Gyeongsang National 
      University, Jinju, Republic of Korea.
FAU - Kim, Woe-Yeon
AU  - Kim WY
AD  - Division of Applied Life Science (BK21Plus), RILS & IALS, Gyeongsang National 
      University, Jinju, Republic of Korea.
FAU - Hwang, Inhwan
AU  - Hwang I
AUID- ORCID: 0000-0002-1388-1367
AD  - Division of Integrative Biosciences and Biotechnology, Pohang University of 
      Science and Technology, Pohang, South Korea.
AD  - Department of Life Science, Pohang University of Science and Technology, Pohang, 
      South Korea.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210707
PL  - United States
TA  - Plant Cell Environ
JT  - Plant, cell & environment
JID - 9309004
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (GLK1 protein, Arabidopsis)
RN  - 0 (Plant Growth Regulators)
RN  - 0 (Transcription Factors)
RN  - 72S9A8J5GW (Abscisic Acid)
RN  - EC 2.3.2.27 (AT2G32950 protein, Arabidopsis)
RN  - EC 2.3.2.27 (Ubiquitin-Protein Ligases)
SB  - IM
MH  - Abscisic Acid/*metabolism
MH  - Arabidopsis/physiology
MH  - Arabidopsis Proteins/metabolism/*physiology
MH  - Chloroplasts/*physiology
MH  - Dimerization
MH  - Dose-Response Relationship, Radiation
MH  - Light
MH  - Plant Growth Regulators/*physiology
MH  - Transcription Factors/metabolism/*physiology
MH  - Ubiquitin-Protein Ligases/metabolism/*physiology
MH  - Ubiquitination
OTO - NOTNLM
OT  - Arabidopsis thaliana
OT  - Golden2-like 1 (GLK1)
OT  - chloroplast development
OT  - light intensity
OT  - long-term abiotic stress
EDAT- 2021/06/16 06:00
MHDA- 2021/12/15 06:00
CRDT- 2021/06/15 13:44
PHST- 2021/06/12 00:00 [revised]
PHST- 2021/05/01 00:00 [received]
PHST- 2021/06/12 00:00 [accepted]
PHST- 2021/06/16 06:00 [pubmed]
PHST- 2021/12/15 06:00 [medline]
PHST- 2021/06/15 13:44 [entrez]
AID - 10.1111/pce.14130 [doi]
PST - ppublish
SO  - Plant Cell Environ. 2021 Sep;44(9):3034-3048. doi: 10.1111/pce.14130. Epub 2021 
      Jul 7.