PMID- 34130392
OWN - NLM
STAT- MEDLINE
DCOM- 20210629
LR  - 20210629
IS  - 1042-7260 (Print)
IS  - 1042-7260 (Linking)
VI  - 52
IP  - 2
DP  - 2021 Jun
TI  - DETERMINATION OF VERTEBRAL HEART SCALE AND ECHOCARDIOGRAPHIC MEASUREMENTS IN 
      HEALTHY ANESTHETIZED AFRICAN WILD DOGS (LYCAON PICTUS) IN HUMAN CARE.
PG  - 499-506
LID - 10.1638/2020-0080 [doi]
AB  - Cardiac disease is an important cause of mortality in African wild dogs in human 
      care. Vertebral heart scale (VHS) is a well-documented objective measure of 
      cardiac size and is commonly used in domestic dogs. The VHS of 63 clinically 
      healthy African wild dogs housed in zoological institutions was retrospectively 
      calculated. Using the robust method of reference interval (RI) calculation, the 
      RI for VHS in captive African wild dogs was 9.3-10.8. Echocardiographic 
      measurements from 16 clinically healthy and 2 African wild dogs with preclinical 
      dilated cardiomyopathy are reported. The cardiac biomarkers N-terminal pro-B-type 
      natriuretic peptide (NT-proBNP) and cardiac troponin I (cTnI) were measured in a 
      subset of African wild dogs. The median plasma NT-proBNP measurement was 845 pM/L 
      (range 366-1,388) and the median serum cTnI measurement was 0.02 ng/ml 
      (0.01-0.04). These data can be used for the assessment and identification of 
      cardiac disease in this endangered species.
FAU - O'Connor, Luke
AU  - O'Connor L
AD  - Bristol Veterinary School, University of Bristol, Langford House, Langford, 
      Bristol BS40 5DU, United Kingdom, lukeoconnorvet@gmail.com.
FAU - Hard, Therese
AU  - Hard T
AD  - Boras Zoo, Alidelundsgatan 11, 506 31 Boras, Sweden.
FAU - Baumwart, Ryan
AU  - Baumwart R
AD  - Department of Veterinary Clinical Sciences, College of Veterinary Medicine, 
      Washington State University, Pullman, WA 99164, USA.
FAU - D'Agostino, Jennifer
AU  - D'Agostino J
AD  - Oklahoma City Zoo, Oklahoma City, OK 73111, USA.
FAU - Hezzell, Melanie
AU  - Hezzell M
AD  - Bristol Veterinary School, University of Bristol, Langford House, Langford, 
      Bristol BS40 5DU, United Kingdom.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Zoo Wildl Med
JT  - Journal of zoo and wildlife medicine : official publication of the American 
      Association of Zoo Veterinarians
JID - 8915208
RN  - 0 (Biomarkers)
RN  - 0 (Peptide Fragments)
RN  - 0 (Troponin)
RN  - 0 (pro-brain natriuretic peptide (1-76))
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
SB  - IM
MH  - Anesthesia/*veterinary
MH  - Animals
MH  - Animals, Zoo
MH  - Biomarkers
MH  - *Canidae
MH  - Echocardiography/*veterinary
MH  - Female
MH  - Heart/*anatomy & histology
MH  - Male
MH  - Natriuretic Peptide, Brain/blood
MH  - Peptide Fragments/blood
MH  - Troponin/blood
EDAT- 2021/06/17 06:00
MHDA- 2021/06/30 06:00
CRDT- 2021/06/16 02:20
PHST- 2021/01/05 00:00 [accepted]
PHST- 2021/06/16 02:20 [entrez]
PHST- 2021/06/17 06:00 [pubmed]
PHST- 2021/06/30 06:00 [medline]
AID - 10.1638/2020-0080 [doi]
PST - ppublish
SO  - J Zoo Wildl Med. 2021 Jun;52(2):499-506. doi: 10.1638/2020-0080.