PMID- 34131473
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210617
IS  - 1948-5182 (Print)
IS  - 1948-5182 (Electronic)
VI  - 13
IP  - 5
DP  - 2021 May 27
TI  - Endoscopic retrograde cholangiopancreatography drainage for palliation of 
      malignant hilar biliary obstruction - stent-in-stent or side-by-side? A 
      systematic review and meta-analysis.
PG  - 595-610
LID - 10.4254/wjh.v13.i5.595 [doi]
AB  - BACKGROUND: Biliary drainage, either by the stent-in-stent (SIS) or side-by-side 
      (SBS) technique, is often required when treating a malignant hilar biliary 
      obstruction (MHBO). Both methods differ from each other and have distinct 
      advantages. AIM: To compare both techniques regarding their efficacy and safety 
      in achieving drainage of MHBO. METHODS: A comprehensive search of multiple 
      electronic databases (MEDLINE, Embase, LILACS, BIREME, Cochrane) was conducted 
      and grey literature from their inception until December 2020 with no restrictions 
      regarding the year of publication or language, since there was at least an 
      abstract in English. The included studies compared SIS and SBS techniques through 
      endoscopic retrograde cholangiopancreatography. Outcomes analyzed included 
      technical and clinical success, early and late adverse events (AEs), stent 
      patency, reintervention, and procedure-related mortality. RESULTS: Four cohort 
      studies and one randomized controlled trial evaluating a total of 250 patients 
      (127 in the SIS group and 123 in the SBS group) were included in this study. 
      There were no statistically significant differences between the two groups 
      concerning the evaluated outcomes, except for stent patency, which was higher in 
      the SIS compared with the SBS technique [mean difference (d) = 33.31; 95% 
      confidence interval: 9.73 to 56.90, I (2) = 45%, P = 0.006]. CONCLUSION: The SIS 
      method showed superior stent patency when compared to SBS for achieving bilateral 
      drainage in MHBO. Both techniques are equivalent in terms of technical success, 
      clinical success, rates of both early and late AEs, reintervention, and 
      procedure-related mortality.
CI  - (c)The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights 
      reserved.
FAU - de Souza, Gabriel Mayo Vieira
AU  - de Souza GMV
AD  - Gastrointestinal Endoscopy Unit, Hospital das Clinicas da Faculdade de Medicina 
      da Universidade de Sao Paulo, Sao Paulo 05403-010, Brazil.
FAU - Ribeiro, Igor Braga
AU  - Ribeiro IB
AD  - Gastrointestinal Endoscopy Unit, Hospital das Clinicas da Faculdade de Medicina 
      da Universidade de Sao Paulo, Sao Paulo 05403-010, Brazil. igorbraga1@gmail.com.
FAU - Funari, Mateus Pereira
AU  - Funari MP
AD  - Gastrointestinal Endoscopy Unit, Hospital das Clinicas da Faculdade de Medicina 
      da Universidade de Sao Paulo, Sao Paulo 05403-010, Brazil.
FAU - de Moura, Diogo Turiani Hourneaux
AU  - de Moura DTH
AD  - Gastrointestinal Endoscopy Unit, Hospital das Clinicas da Faculdade de Medicina 
      da Universidade de Sao Paulo, Sao Paulo 05403-010, Brazil.
FAU - Scatimburgo, Maria Vitoria Cury Vieira
AU  - Scatimburgo MVCV
AD  - Gastrointestinal Endoscopy Unit, Hospital das Clinicas da Faculdade de Medicina 
      da Universidade de Sao Paulo, Sao Paulo 05403-010, Brazil.
FAU - de Freitas Junior, Joao Remi
AU  - de Freitas Junior JR
AD  - Gastrointestinal Endoscopy Unit, Hospital das Clinicas da Faculdade de Medicina 
      da Universidade de Sao Paulo, Sao Paulo 05403-010, Brazil.
FAU - Sanchez-Luna, Sergio A
AU  - Sanchez-Luna SA
AD  - Division of Gastroenterology, Hepatology and Nutrition, Center for Advanced 
      Therapeutic Endoscopy, Allegheny Health Network, Pittsburgh, PA 15212, United 
      States.
FAU - Baracat, Renato
AU  - Baracat R
AD  - Gastrointestinal Endoscopy Unit, Hospital das Clinicas da Faculdade de Medicina 
      da Universidade de Sao Paulo, Sao Paulo 05403-010, Brazil.
FAU - de Moura, Eduardo Turiani Hourneaux
AU  - de Moura ETH
AD  - Gastrointestinal Endoscopy Unit, Hospital das Clinicas da Faculdade de Medicina 
      da Universidade de Sao Paulo, Sao Paulo 05403-010, Brazil.
FAU - Bernardo, Wanderley Marques
AU  - Bernardo WM
AD  - Gastrointestinal Endoscopy Unit, Hospital das Clinicas da Faculdade de Medicina 
      da Universidade de Sao Paulo, Sao Paulo 05403-010, Brazil.
FAU - de Moura, Eduardo Guimaraes Hourneaux
AU  - de Moura EGH
AD  - Gastrointestinal Endoscopy Unit, Hospital das Clinicas da Faculdade de Medicina 
      da Universidade de Sao Paulo, Sao Paulo 05403-010, Brazil.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - World J Hepatol
JT  - World journal of hepatology
JID - 101532469
PMC - PMC8173339
OTO - NOTNLM
OT  - Biliary
OT  - Biliary tract neoplasms
OT  - Drainage
OT  - Endoscopic retrograde cholangiopancreatography
OT  - Hilar
OT  - Stenting
COIS- Conflict-of-interest statement: The authors deny any conflict of interest.
EDAT- 2021/06/17 06:00
MHDA- 2021/06/17 06:01
PMCR- 2021/05/27
CRDT- 2021/06/16 06:48
PHST- 2021/01/13 00:00 [received]
PHST- 2021/03/11 00:00 [revised]
PHST- 2021/03/18 00:00 [accepted]
PHST- 2021/06/16 06:48 [entrez]
PHST- 2021/06/17 06:00 [pubmed]
PHST- 2021/06/17 06:01 [medline]
PHST- 2021/05/27 00:00 [pmc-release]
AID - 10.4254/wjh.v13.i5.595 [doi]
PST - ppublish
SO  - World J Hepatol. 2021 May 27;13(5):595-610. doi: 10.4254/wjh.v13.i5.595.