PMID- 34134136
OWN - NLM
STAT- MEDLINE
DCOM- 20220322
LR  - 20220322
IS  - 1460-2377 (Electronic)
IS  - 0953-8178 (Linking)
VI  - 33
IP  - 12
DP  - 2021 Nov 25
TI  - Commitment to dendritic cells and monocytes.
PG  - 815-819
LID - 10.1093/intimm/dxab031 [doi]
AB  - Dendritic cells (DCs) and monocytes are widely conserved immune cells in 
      vertebrates that arise from hematopoietic stem cells via intermediate 
      progenitors. The progenitors that strictly give rise to DCs or monocytes have 
      been recently identified both in humans and in mice, thereby revealing their 
      differentiation pathways. Advances in analysis technologies have further deepened 
      our understanding of the development of DCs and monocytes from progenitor 
      population-based to individual progenitor cell-based commitment. Since 
      DC-committed progenitors, common DC progenitors (CDPs) and precursor conventional 
      DCs (pre-cDCs) do not differentiate into monocytes, DCs are a distinct lineage 
      from monocytes, although monocytes can acquire DC functions upon activation at 
      tissues where they arrive.
CI  - (c) The Japanese Society for Immunology. 2021. All rights reserved. For 
      permissions, please e-mail: journals.permissions@oup.com.
FAU - Ohteki, Toshiaki
AU  - Ohteki T
AD  - Department of Biodefense Research, Medical Research Institute, Tokyo Medical and 
      Dental University, Tokyo, Japan.
FAU - Kawamura, Shunsuke
AU  - Kawamura S
AD  - Department of Biosystems Science and Engineering (D-BSSE), ETH Zurich, Basel, 
      Switzerland.
FAU - Onai, Nobuyuki
AU  - Onai N
AD  - Department of Immunology, Kanazawa Medical University, Ishikawa, Japan.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Int Immunol
JT  - International immunology
JID - 8916182
SB  - IM
MH  - Animals
MH  - Dendritic Cells/*immunology
MH  - Humans
MH  - Monocytes/*immunology
OTO - NOTNLM
OT  - CDP
OT  - CLP
OT  - GMP
OT  - cMoP
EDAT- 2021/06/17 06:00
MHDA- 2022/03/23 06:00
CRDT- 2021/06/16 20:16
PHST- 2021/06/06 00:00 [received]
PHST- 2021/06/14 00:00 [accepted]
PHST- 2021/06/17 06:00 [pubmed]
PHST- 2022/03/23 06:00 [medline]
PHST- 2021/06/16 20:16 [entrez]
AID - 6301137 [pii]
AID - 10.1093/intimm/dxab031 [doi]
PST - ppublish
SO  - Int Immunol. 2021 Nov 25;33(12):815-819. doi: 10.1093/intimm/dxab031.