PMID- 34135664 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220424 IS - 1319-0164 (Print) IS - 2213-7475 (Electronic) IS - 1319-0164 (Linking) VI - 29 IP - 5 DP - 2021 May TI - Saudi cultural adaptation of the "compliance questionnaire of Rheumatology" for Rheumatoid arthritis patients on disease modifying anti-rheumatic drugs (DMARDs). PG - 377-383 LID - 10.1016/j.jsps.2021.03.007 [doi] AB - PURPOSE: This study aims to develop a valid and reliable Arabic version of the Compliance Questionnaire on Rheumatology (CQR-A) and to explore the impact of demographic factors on compliance. METHODS: This is a descriptive cross-sectional study carried out at the outpatient clinics of rheumatology in King Fahad hospital (KFH) in Madinah, Saudi Arabia, from May 2019 to October 2019. Initially, the original version was culturally adapted to an Arabic version by forward translation, backward translation, committee review of both the Arabic and the original versions, and lastly, pre-testing. Then, seventy-two rheumatoid arthritis patients were recruited to evaluate the reliability and validity of the CQR-A. Reliability was assessed by the test-retest method with a two-week interval through the intraclass correlation coefficient (ICC). The criterion validity of the CQR-A was assessed through Pearson correlation of pharmacy refill and CQR-A. The content validity index (CVI) was used to determine content validity. Multiple regression analysis was done to evaluate the effect of demographic factors on compliance. RESULTS: The CQR-A has adequate reliability and validity. The ICC = 0.757 with a 95% CI ranging from 0.579 to 0.860, p < 0.001, Cronbach's alpha coefficient = 0.788. Pearson correlation coefficient was found to be (r = 0.338, p = 0.013). The individual content validity index (I-CVI) ranged from 0.67 to 1.00, and the average scale content validity index (S-CVI/Ave) = 0.91. Education was the only significant predictor of compliance amongst the demographic factors with R2 of 0.158. CONCLUSION: The Arabic version of the Compliance Questionnaire on Rheumatology (CQR-A) is a reliable and valid clinical tool to assess compliance in Arabic speaking patients. CI - (c) 2021 The Authors. FAU - Aljohani, Roaa AU - Aljohani R AD - Department of medicine, College of Medicine, Taibah University, Madinah, Saudi Arabia. FAU - Aljohani, Zeyad AU - Aljohani Z AD - Department of rheumatology, King Fahad hospital, Madinah, Saudi Arabia. FAU - Aljohani, Rawan AU - Aljohani R AD - College of medicine, Taibah University, Madinah, Saudi Arabia. FAU - Alsaidalani, Raghad AU - Alsaidalani R AD - College of medicine, Taibah University, Madinah, Saudi Arabia. LA - eng PT - Journal Article DEP - 20210324 PL - Saudi Arabia TA - Saudi Pharm J JT - Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society JID - 9705695 PMC - PMC8180466 OTO - NOTNLM OT - Arabic OT - Compliance questionnaire OT - Demographic factors OT - Rheumatoid arthritis OT - Saudi COIS- The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2021/06/18 06:00 MHDA- 2021/06/18 06:01 PMCR- 2021/03/24 CRDT- 2021/06/17 06:39 PHST- 2020/10/13 00:00 [received] PHST- 2021/03/06 00:00 [accepted] PHST- 2021/06/17 06:39 [entrez] PHST- 2021/06/18 06:00 [pubmed] PHST- 2021/06/18 06:01 [medline] PHST- 2021/03/24 00:00 [pmc-release] AID - S1319-0164(21)00046-3 [pii] AID - 10.1016/j.jsps.2021.03.007 [doi] PST - ppublish SO - Saudi Pharm J. 2021 May;29(5):377-383. doi: 10.1016/j.jsps.2021.03.007. Epub 2021 Mar 24.