PMID- 34143805
OWN - NLM
STAT- MEDLINE
DCOM- 20211116
LR  - 20211116
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 16
IP  - 6
DP  - 2021
TI  - Genetic parameters for milk urea and its relationship with milk yield and 
      compositions in Holstein dairy cows.
PG  - e0253191
LID - 10.1371/journal.pone.0253191 [doi]
LID - e0253191
AB  - The aim was to estimate genetic parameters for milk urea (MU) concentration and 
      its relationship with milk yield and compositions in Holstein dairy Cows. Edited 
      data were 90,594 test-day records of milk yield and composition collected during 
      2015 to 2018 on 13,737 lactations obtained from 7,850 Holstein cows in 50 herds. 
      Random regression test-day model was used to estimate genetic parameters. 
      (Co)variance components were estimated with the Bayesian Gibbs sampling method 
      using a single chain of 400,000 iterates. The first 50,000 iterates of each chain 
      were regarded as a burn-in period. Mean (SD) of MU was 23.03 (5.99) and 22.41 
      (5.74) mg/dl in primiparous and multiparous cows, respectively. Average 
      heritability estimates for daily MU was 0.33 (SD = 0.02) ranged 0.29 to 0.36 and 
      0.32 (SD = 0.03) ranged 0.27 to 0.34, respectively, for primiparous and 
      multiparous cows. The mean (SD) genetic correlation between MU and milk yield, 
      fat yield, protein yield, lactose yield, fat percentage, protein percentage, 
      lactose percentage, and somatic cell score was, respectively, -0.02 (0.03), -0.02 
      (0.01), 0.01 (0.04), 0.01 (0.03), 0.00 (0.07), -0.03 (0.04), 0.00 (0.01), -0.11 
      (0.06) in primiparous cows. The corresponding values in multiparous cows were 
      -0.01 (0.02), -0.01 (0.03), -0.04 (0.04), -0.04 (0.04), 0.04 (0.04), 0.04 (0.07), 
      -0.03 (0.09), 0.06 (0.11), respectively. The results indicate that selection on 
      MU is possible with no effect on milk yield or compositions, however, 
      relationships between MU and other important traits such as longevity, metabolic 
      diseases, and fertility are needed.
FAU - Atashi, Hadi
AU  - Atashi H
AUID- ORCID: 0000-0002-6853-6608
AD  - Department of Animal Science, Shiraz University, Shiraz, Iran.
FAU - Hostens, Miel
AU  - Hostens M
AUID- ORCID: 0000-0001-5376-976X
AD  - Department of Farm Animal Health, University of Utrecht, Utrecht, The 
      Netherlands.
CN  - GplusE consortium
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210618
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
RN  - 0 (Fats)
RN  - 8W8T17847W (Urea)
SB  - IM
MH  - Animals
MH  - Bayes Theorem
MH  - Cattle
MH  - Fats/*analysis
MH  - Female
MH  - Milk/*chemistry
MH  - Urea/*analysis
PMC - PMC8213141
COIS- The authors have declared that no competing interests exist.
EDAT- 2021/06/19 06:00
MHDA- 2021/11/17 06:00
PMCR- 2021/06/18
CRDT- 2021/06/18 17:18
PHST- 2021/04/02 00:00 [received]
PHST- 2021/05/31 00:00 [accepted]
PHST- 2021/06/18 17:18 [entrez]
PHST- 2021/06/19 06:00 [pubmed]
PHST- 2021/11/17 06:00 [medline]
PHST- 2021/06/18 00:00 [pmc-release]
AID - PONE-D-21-10738 [pii]
AID - 10.1371/journal.pone.0253191 [doi]
PST - epublish
SO  - PLoS One. 2021 Jun 18;16(6):e0253191. doi: 10.1371/journal.pone.0253191. 
      eCollection 2021.