PMID- 34145003 OWN - NLM STAT- MEDLINE DCOM- 20210624 LR - 20210702 IS - 2044-6055 (Electronic) IS - 2044-6055 (Linking) VI - 11 IP - 6 DP - 2021 Jun 18 TI - Caregiver burden versus intensity of anxiety and depression symptoms in parents of children with cerebral palsy as well as factors potentially differentiating the level of burden: a cross-sectional study (Poland). PG - e036494 LID - 10.1136/bmjopen-2019-036494 [doi] LID - e036494 AB - OBJECTIVES: To assess the relationship between caregiver burden and severity of symptoms of anxiety/depression in parents of children with cerebral palsy (CP), and to identify factors differentiating the level of caregiver burden. SETTING: Regional rehabilitation centres in South-Eastern Poland. PARTICIPANTS: The study involved 190 parents of children with CP, that is, 138 women and 52 men. PRIMARY AND SECONDARY OUTCOME MEASURES: Caregiver burden was assessed using Caregiver Burden Scale (CBS), while the intensity of anxiety and depression symptoms was measured using Hospital Anxiety and Depression Scale (HADS). Potential predictors were examined using Gross Motor Function Classification System for Cerebral Palsy (GMFCS), Barthel Index (BI) as well as a questionnaire focusing on the characteristics of the child, the parent and the family. The analyses applied Pearson's linear correlation coefficient as well as multiple regression analysis. RESULTS: All the CBS measures are significantly correlated to HADS-A (anxiety) and HADS-D (depression). Intensity of anxiety is most visibly linked to CBS measures of disappointment and environment (p<0.0001), while severity of depression is related to emotional involvement and general strain (p<0.0001). The factors differentiating caregiver burden measure in the subscales of general strain (p<0.0001) and social isolation (p<0.0001) include the child's age and BI, and the parent's health status; in the subscale of disappointment (p<0.0001)-the child's age, BI, GMFCS, as well as the parent's age and health status; in the subscale of emotional involvement (p=0.0007)-BI, and the parent's health status; in the subscale of environment (p=0.0002)-the child's age and BI. CONCLUSIONS: There is a positive linear relationship between the caregiver burden measures and severity of anxiety and depression. Effort should be made to relieve caregiver burden in parents of children with CP. CI - (c) Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. FAU - Gugala, Barbara AU - Gugala B AUID- ORCID: 0000-0001-5807-0595 AD - Medical College, University of Rzeszow, Rzeszow, Poland bgugala@ur.edu.pl. LA - eng PT - Journal Article DEP - 20210618 PL - England TA - BMJ Open JT - BMJ open JID - 101552874 SB - IM MH - Anxiety MH - Caregiver Burden MH - Caregivers MH - *Cerebral Palsy MH - Child MH - Cross-Sectional Studies MH - *Depression MH - Female MH - Humans MH - Male MH - Parents MH - Poland MH - Surveys and Questionnaires PMC - PMC8215253 OTO - NOTNLM OT - anxiety disorders OT - depression & mood disorders OT - preventive medicine OT - public health COIS- Competing interests: None declared. EDAT- 2021/06/20 06:00 MHDA- 2021/06/25 06:00 PMCR- 2021/06/18 CRDT- 2021/06/19 05:39 PHST- 2021/06/19 05:39 [entrez] PHST- 2021/06/20 06:00 [pubmed] PHST- 2021/06/25 06:00 [medline] PHST- 2021/06/18 00:00 [pmc-release] AID - bmjopen-2019-036494 [pii] AID - 10.1136/bmjopen-2019-036494 [doi] PST - epublish SO - BMJ Open. 2021 Jun 18;11(6):e036494. doi: 10.1136/bmjopen-2019-036494.