PMID- 34146981 OWN - NLM STAT- MEDLINE DCOM- 20210712 LR - 20210712 IS - 1090-2414 (Electronic) IS - 0147-6513 (Linking) VI - 221 DP - 2021 Sep 15 TI - Simultaneous determination and risk assessment of highly toxic pesticides in the market-sold vegetables and fruits in China: A 4-year investigational study. PG - 112428 LID - S0147-6513(21)00540-6 [pii] LID - 10.1016/j.ecoenv.2021.112428 [doi] AB - This study investigated the levels of highly toxic pesticides (HTPs) in 6554 vegetable and fruit samples from 31 regions of China, along with the associated risk of dietary exposure for the population between 2014 and 2017. 18 HTPs were detected in 325 (4.96%) samples, and the levels of HTPs in 103 (1.57%) samples were found to be higher than the maximum residue limits (MRLs) of China. The rate of detection of HTPs in six types of vegetables and fruits, in a decreasing order, was found to be as follows: eggplant (8.84%) >grape (5.58%) >tomato (5.43%) >cucumber (5.43%) >pear (3.12%) >apple (2.30%). The level of contamination of HTPs was found to be higher in vegetables compared with fruits. The vegetable and fruit samples with the highest percentages of HTPs exceeding MRLs were found in eggplants from Guangxi (20%) and grapes from Inner Mongolia (12.5%), respectively. Both, the average target hazard quotient (THQ) of a single highly toxic pesticide (HTP) and the average hazard index (HI) of the mixture of HTPs for adults and children from vegetables and fruits from the 31 regions were found to be less than one. Omethoate, carbofuran, ethoprophos, triazophos, and phorate were identified as the major contributors to the average HI for vegetables, and carbofuran, ethoprophos, omethoate, phorate, and phosphamidon were identified as the primary contributors to the average HI for fruits. The results of this study revealed that HTPs in vegetables and fruits did not cause any significant chronic risk of dietary exposure. The detection of HTPs exceeding MRLs in some of the samples implied that appropriate management guidelines for HTPs should be implemented to protect the health of the consumers. CI - Copyright (c) 2021 The Authors. Published by Elsevier Inc. All rights reserved. FAU - Li, Hui AU - Li H AD - College of Chemistry and Environmental Science, Institute of Life Science and Green Development, Hebei University, 071002, China. Electronic address: lihui2006.cool@163.com. FAU - Chang, Qiaoying AU - Chang Q AD - College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China. FAU - Bai, Ruobin AU - Bai R AD - Beijing Uni-Star Inspection Technology Co., Ltd., Beijing 100176, China. FAU - Lv, Xuechong AU - Lv X AD - College of Chemistry and Environmental Science, Institute of Life Science and Green Development, Hebei University, 071002, China. FAU - Cao, Tengliang AU - Cao T AD - College of Chemistry and Environmental Science, Institute of Life Science and Green Development, Hebei University, 071002, China. FAU - Shen, Shigang AU - Shen S AD - College of Chemistry and Environmental Science, Institute of Life Science and Green Development, Hebei University, 071002, China. FAU - Liang, Shuxuan AU - Liang S AD - College of Chemistry and Environmental Science, Institute of Life Science and Green Development, Hebei University, 071002, China. Electronic address: liangsx168@126.com. FAU - Pang, Guofang AU - Pang G AD - College of Chemistry and Environmental Science, Institute of Life Science and Green Development, Hebei University, 071002, China; Chinese Academy of Inspection and Quarantine, Beijing 100176, China. Electronic address: ciqpang@163.com. LA - eng PT - Journal Article DEP - 20210617 PL - Netherlands TA - Ecotoxicol Environ Saf JT - Ecotoxicology and environmental safety JID - 7805381 RN - 0 (Pesticide Residues) SB - IM MH - Adult MH - Child MH - China MH - Dietary Exposure/*statistics & numerical data MH - Food Contamination/analysis MH - Fruit/*chemistry MH - Humans MH - Pesticide Residues/*analysis MH - *Risk Assessment MH - Vegetables/*chemistry OTO - NOTNLM OT - Dietary risk assessment OT - Fruits OT - Highly toxic pesticides OT - Maximum residue limit OT - Vegetables EDAT- 2021/06/20 06:00 MHDA- 2021/07/13 06:00 CRDT- 2021/06/19 20:25 PHST- 2021/03/09 00:00 [received] PHST- 2021/06/10 00:00 [revised] PHST- 2021/06/13 00:00 [accepted] PHST- 2021/06/20 06:00 [pubmed] PHST- 2021/07/13 06:00 [medline] PHST- 2021/06/19 20:25 [entrez] AID - S0147-6513(21)00540-6 [pii] AID - 10.1016/j.ecoenv.2021.112428 [doi] PST - ppublish SO - Ecotoxicol Environ Saf. 2021 Sep 15;221:112428. doi: 10.1016/j.ecoenv.2021.112428. Epub 2021 Jun 17.