PMID- 34147275
OWN - NLM
STAT- MEDLINE
DCOM- 20210902
LR  - 20211204
IS  - 1773-0597 (Electronic)
IS  - 0181-5512 (Linking)
VI  - 44
IP  - 7
DP  - 2021 Sep
TI  - Visual field defects due to optic nerve drusen in Afro-Caribbean patients: A case 
      series of 16 eyes.
PG  - 989-994
LID - S0181-5512(21)00280-1 [pii]
LID - 10.1016/j.jfo.2020.10.023 [doi]
AB  - INTRODUCTION: Optic Nerve Head Drusen (ONHD) are very rare among black patients 
      but may cause more severe visual defects in these patients. The goal of our study 
      was to describe the frequency of visual field defects secondary to OND in 
      Afro-Caribbean patients and study the characteristics of their physical 
      examination, color vision and contrast sensitivity. METHODS: We carried out a 
      prospective study at the Martinique university medical center on patients of 
      African descent with ONHD diagnosed on fundus examination and B-scan 
      ultrasonography. All patients received a complete neuro-ophthalmological 
      examination. The primary study endpoint was the frequency of visual field 
      defects. Secondary study endpoints were the results of ETDRS visual acuity, 
      Pelli-Robson contrast sensitivity chart, and 15 hue color vision test. RESULTS: 
      Sixteen eyes of 10 patients from 11 to 68 years of age were included. Forteen 
      eyes (87%) had exposed ONHD. Eleven eyes (69%) showed a visual field defect: 9 
      eyes (69%) had an enlarged blind spot, and 9 eyes (69%) had an arcuate scotoma. 3 
      eyes (19%) had loss of ETDRS visual acuity, and 12 eyes (75%) showed loss of 
      Pelli-Robson contrast sensitivity. Five eyes (31%) had an abnormal color vision 
      test. CONCLUSION: This is one of the largest case series of ONHD in Black 
      patients. The frequency of visual field defects was high but comparable to that 
      of studies in other ethnic groups. Larger comparative studies are necessary to 
      confirm these results.
CI  - Copyright (c) 2021 Elsevier Masson SAS. All rights reserved.
FAU - Sustronck, P
AU  - Sustronck P
AD  - Hopital Saint Joseph, France. Electronic address: pierre.sustronck@gmail.com.
FAU - Nguyen, D T
AU  - Nguyen DT
AD  - Necker Hospital, Paris, France.
FAU - Jean-Charles, A
AU  - Jean-Charles A
AD  - University Hospital of Martinique, Fort de France, Martinique.
FAU - David, T
AU  - David T
AD  - University Hospital of Martinique, Fort de France, Martinique.
FAU - Merle, H
AU  - Merle H
AD  - University Hospital of Martinique, Fort de France, Martinique.
LA  - eng
PT  - Journal Article
DEP - 20210617
PL  - France
TA  - J Fr Ophtalmol
JT  - Journal francais d'ophtalmologie
JID - 7804128
SB  - IM
MH  - Caribbean Region
MH  - Ethnicity
MH  - Humans
MH  - *Optic Disk Drusen/complications/diagnosis
MH  - Prospective Studies
MH  - Tomography, Optical Coherence
MH  - Visual Fields
OTO - NOTNLM
OT  - Afro-Caribbean
OT  - Afro-caribeens
OT  - Antillais
OT  - Antilles
OT  - Drusen du nerf optique
OT  - Deficit campimetrique.
OT  - Optic nerve drusen
OT  - Visual field defects
EDAT- 2021/06/21 06:00
MHDA- 2021/09/03 06:00
CRDT- 2021/06/20 20:28
PHST- 2020/07/25 00:00 [received]
PHST- 2020/08/19 00:00 [revised]
PHST- 2020/10/05 00:00 [accepted]
PHST- 2021/06/21 06:00 [pubmed]
PHST- 2021/09/03 06:00 [medline]
PHST- 2021/06/20 20:28 [entrez]
AID - S0181-5512(21)00280-1 [pii]
AID - 10.1016/j.jfo.2020.10.023 [doi]
PST - ppublish
SO  - J Fr Ophtalmol. 2021 Sep;44(7):989-994. doi: 10.1016/j.jfo.2020.10.023. Epub 2021 
      Jun 17.