PMID- 34154915 OWN - NLM STAT- MEDLINE DCOM- 20230919 LR - 20230919 IS - 1873-4588 (Electronic) IS - 0892-1997 (Linking) VI - 37 IP - 5 DP - 2023 Sep TI - Perception of Proton Pump Inhibitor Side Effects Among Members of the American Broncho-Esophagological Association. PG - 757-763 LID - S0892-1997(21)00173-9 [pii] LID - 10.1016/j.jvoice.2021.05.006 [doi] AB - OBJECTIVES: To investigate awareness of proton pump inhibitor (PPI) side effects and the resulting changes in reflux mana management among members of the American Broncho-Esophagological Association (ABEA) caring for adult patients in light of increasing concern for PPIs long-term adverse effects. STUDY DESIGN: Cross-sectional survey study METHODS: Online surveys were electronically distributed to ABEA members assessing awareness of PPI side effects and current practice in reflux management. RESULTS: 374 ABEA members were contacted, of whom, 43 (11.5%) completed the survey. The majority of respondents (94.1%) selected laryngology as their principal focus. The entire cohort warned their patients about PPI side effects, with highest concern for osteoporotic risk. Most respondents (88.2%) had changed their PPI prescription frequency in light of recent studies on PPI side effects, with 55.9% avoiding PPI prescription and 94.1% limiting the duration of PPI courses. Instead of PPIs, 73.5% of responders prescribe H2-receptor blockers. The primary reasons for starting patients on PPIs were typical gastroesophageal reflux symptoms (47.1%), followed by laryngopharyngeal reflux symptoms (41.2%), and endoscopic findings suspicious for reflux (11.8%). Finally, the majority of respondents (82.4%) had referred at least one patient for surgical management of gastroesophageal reflux in the past year. CONCLUSIONS: The majority of surveyed ABEA members were concerned about reports of PPI adverse effects and had modified their prescription patterns as a result. Avoidance of PPI recommendation was common, along with the preference for H2 blockers in the management of GERD and LPR. PPI side effects of greatest concern to broncho-esophagologists treating adult patients were osteoporosis, renal dysfunction and dementia. CI - Copyright (c) 2021 The Voice Foundation. Published by Elsevier Inc. All rights reserved. FAU - Rameau, Anais AU - Rameau A AD - Sean Parker Institute for the Voice, Department of Otolaryngology, Head & Neck Surgery, Weill Cornell Medical College, New York, NY. Electronic address: anr2783@med.cornell.edu. FAU - Lee, Mark AU - Lee M AD - Sean Parker Institute for the Voice, Department of Otolaryngology, Head & Neck Surgery, Weill Cornell Medical College, New York, NY. FAU - Andreadis, Katerina AU - Andreadis K AD - Sean Parker Institute for the Voice, Department of Otolaryngology, Head & Neck Surgery, Weill Cornell Medical College, New York, NY. FAU - Sulica, Lucian AU - Sulica L AD - Sean Parker Institute for the Voice, Department of Otolaryngology, Head & Neck Surgery, Weill Cornell Medical College, New York, NY. LA - eng PT - Journal Article DEP - 20210619 PL - United States TA - J Voice JT - Journal of voice : official journal of the Voice Foundation JID - 8712262 RN - 0 (Proton Pump Inhibitors) SB - IM MH - Adult MH - Humans MH - United States MH - Proton Pump Inhibitors/adverse effects MH - Cross-Sectional Studies MH - *Laryngopharyngeal Reflux/diagnosis MH - Surveys and Questionnaires MH - *Drug-Related Side Effects and Adverse Reactions MH - Perception OTO - NOTNLM OT - Gastroesophageal Reflux Disease OT - Laryngopharyngeal reflux OT - Prescription patterns OT - Proton pump inhibitors EDAT- 2021/06/23 06:00 MHDA- 2023/09/19 06:43 CRDT- 2021/06/22 05:49 PHST- 2021/03/25 00:00 [received] PHST- 2021/04/27 00:00 [revised] PHST- 2021/05/04 00:00 [accepted] PHST- 2023/09/19 06:43 [medline] PHST- 2021/06/23 06:00 [pubmed] PHST- 2021/06/22 05:49 [entrez] AID - S0892-1997(21)00173-9 [pii] AID - 10.1016/j.jvoice.2021.05.006 [doi] PST - ppublish SO - J Voice. 2023 Sep;37(5):757-763. doi: 10.1016/j.jvoice.2021.05.006. Epub 2021 Jun 19.