PMID- 34157732
OWN - NLM
STAT- MEDLINE
DCOM- 20210624
LR  - 20220716
IS  - 1833-3516 (Print)
IS  - 2209-1491 (Electronic)
IS  - 1833-3516 (Linking)
VI  - 51
IP  - 2
DP  - 2021 Jun 30
TI  - Oxygen toxicity seizures during United States Navy Treatment Table 6: An 
      acceptable risk in monoplace chambers?
PG  - 167-172
LID - 10.28920/dhm51.2.167-172 [doi]
AB  - INTRODUCTION: Hyperbaric oxygen treatment (HBOT) may be complicated by oxygen 
      toxicity seizures, which typically occur with hyperbaric partial pressures of 
      oxygen exceeding 203 kPa (2 atmospheres absolute). All other hyperbaric units in 
      Australia exclusively use a multiplace chamber when treating with United States 
      Navy Treatment Table 6 (USN TT6) due to this perceived risk. The purpose of this 
      study was to determine the safety of a monoplace chamber when treating 
      decompression illness (DCI) with USN TT6. METHODS: A retrospective review of the 
      medical records of all patients treated at Fiona Stanley Hospital Hyperbaric 
      Medicine Unit with USN TT6 between November 2014 and June 2020 was undertaken. 
      These data were combined with previous results from studies performed at our 
      hyperbaric unit at Fremantle Hospital from 1989 to 2014, creating a data set 
      covering a 30-year period. RESULTS: One thousand treatments with USN TT6 were 
      performed between 1989 and 2020; 331 in a monoplace chamber and 669 in a 
      multiplace chamber. Four seizures occurred: a rate of 0.59% (1/167) in a 
      multiplace chamber; and none in a monoplace chamber, indicating no statistically 
      significant difference between seizures in a monoplace versus multiplace chamber 
      (P = 0.31). CONCLUSIONS: The rate of oxygen toxicity seizures in a monoplace 
      chamber is not significantly higher than for treatment in the multiplace chamber. 
      We conclude that using the monoplace chamber for USN TT6 in selected patients 
      poses an acceptably low seizure risk.
CI  - Copyright: This article is the copyright of the authors who grant Diving and 
      Hyperbaric Medicine a non-exclusive licence to publish the article in electronic 
      and other forms.
FAU - Bonnington, Samantha
AU  - Bonnington S
AD  - Department of Hyperbaric Medicine, Fiona Stanley Hospital, Murdoch, Western 
      Australia.
FAU - Banham, Neil
AU  - Banham N
AD  - Department of Hyperbaric Medicine, Fiona Stanley Hospital, Murdoch, Western 
      Australia.
AD  - Corresponding author: Dr Neil Banham, Department of Hyperbaric Medicine, Fiona 
      Stanley Hospital, 11 Robin Warren Drive, Murdoch WA 6150, Australia, 
      neil.banham@health.wa.gov.au.
FAU - Foley, Kevin
AU  - Foley K
AD  - Department of Hyperbaric Medicine, Fiona Stanley Hospital, Murdoch, Western 
      Australia.
FAU - Gawthrope, Ian
AU  - Gawthrope I
AD  - Department of Hyperbaric Medicine, Fiona Stanley Hospital, Murdoch, Western 
      Australia.
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - Diving Hyperb Med
JT  - Diving and hyperbaric medicine
JID - 101282742
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Australia
MH  - Humans
MH  - *Hyperbaric Oxygenation
MH  - Oxygen
MH  - Retrospective Studies
MH  - Seizures/chemically induced/epidemiology/therapy
MH  - United States
PMC - PMC8426124
OTO - NOTNLM
OT  - Cerebral arterial gas embolism
OT  - Decompression illness
OT  - Diving medicine
OT  - Diving research
OT  - Hyperbaric oxygen treatment
OT  - Pressure chambers
OT  - Recompression
COIS- Conflict of interest and funding: nil
EDAT- 2021/06/23 06:00
MHDA- 2021/06/25 06:00
PMCR- 2022/06/30
CRDT- 2021/06/22 20:27
PHST- 2020/10/07 00:00 [received]
PHST- 2021/02/02 00:00 [accepted]
PHST- 2021/06/22 20:27 [entrez]
PHST- 2021/06/23 06:00 [pubmed]
PHST- 2021/06/25 06:00 [medline]
PHST- 2022/06/30 00:00 [pmc-release]
AID - 10.28920/dhm51.2.167-172 [doi]
PST - ppublish
SO  - Diving Hyperb Med. 2021 Jun 30;51(2):167-172. doi: 10.28920/dhm51.2.167-172.