PMID- 34157739
OWN - NLM
STAT- MEDLINE
DCOM- 20210624
LR  - 20220716
IS  - 1833-3516 (Print)
IS  - 2209-1491 (Electronic)
IS  - 1833-3516 (Linking)
VI  - 51
IP  - 2
DP  - 2021 Jun 30
TI  - Hyperbaric oxygen treatment for toxic epidermal necrolysis: A case report.
PG  - 216-219
LID - 10.28920/dhm51.2.216-219 [doi]
AB  - Toxic epidermal necrolysis (TEN) is a potentially life-threatening muco-cutaneous 
      disease, largely caused by an idiosyncratic reaction to medication or infectious 
      disease, and is characterised by acute necrosis of the epidermis. No definitive 
      consensus regarding the treatment of TEN has been agreed. A 60-year-old woman, 
      diagnosed with multiple myeloma three months prior, was admitted with signs of 
      TEN to the intensive care burns unit. She had been given ciprofloxacin to treat a 
      urinary tract infection. She complained of malaise and pain, with maculopapular 
      and bullous eruptions over her whole body on the third day of ciprofloxacin 
      administration. Her supportive cares included intravenous immunoglobulins, pain 
      control with analgesics, wound care, nutrition, and fluid support. Hyperbaric 
      oxygen treatment (HBOT) was added on the second day of admission. The patient 
      underwent 5 sessions of HBOT at 243.1 kPa (2.4 atmospheres absolute). 
      Desquamation was noted to stop after the first session of HBOT and 
      re-epithelisation commenced rapidly. The patient was discharged from the burn 
      unit after 14 days of hospital admission. Improvement in this case was temporally 
      related to the initiation of HBOT.
CI  - Copyright: This article is the copyright of the authors who grant Diving and 
      Hyperbaric Medicine a non-exclusive licence to publish the article in electronic 
      and other forms.
FAU - Gamze Sumen, Selin
AU  - Gamze Sumen S
AD  - University of Health Sciences, Hamidiye Medical Faculty, Department of Underwater 
      and Hyperbaric Medicine, Istanbul, Turkey.
AD  - Corresponding author: Dr Selin Gamze Sumen, Saglik Bilimleri Universitesi, 
      Hamidiye Tip Fakultesi, Sultan 2. Abdulhamid Han Egitim ve Arastirma Hastanesi, 
      Selimiye Mh., Tibbiye Cd., 34668, Uskudar/Istanbul, Turkey, sgsumen@gmail.com.
FAU - Yakupoglu, Sezer
AU  - Yakupoglu S
AD  - University of Health Sciences, Kartal Dr Lutfi Kirdar City Hospital, Department 
      of Anesthesiology and Reanimation, Istanbul, Turkey.
FAU - Gumus, Tuna
AU  - Gumus T
AD  - University of Health Sciences, Kartal Dr Lutfi Kirdar City Hospital, Department 
      of Underwater and Hyperbaric Medicine, Istanbul, Turkey.
FAU - Benzonana, Nur
AU  - Benzonana N
AD  - University of Health Sciences, Kartal Dr Lutfi Kirdar City Hospital, Department 
      of Infectious Diseases and Clinical Microbiology, Istanbul, Turkey.
LA  - eng
PT  - Case Reports
PL  - Australia
TA  - Diving Hyperb Med
JT  - Diving and hyperbaric medicine
JID - 101282742
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Critical Care
MH  - Female
MH  - Humans
MH  - *Hyperbaric Oxygenation
MH  - Middle Aged
MH  - Oxygen
MH  - *Stevens-Johnson Syndrome/therapy
PMC - PMC8426128
OTO - NOTNLM
OT  - Case reports
OT  - Drugs
OT  - Hyperbaric medicine
OT  - Outcome
OT  - Side effects
OT  - Skin
OT  - Toxicity
COIS- Conflict of interest and funding: nil
EDAT- 2021/06/23 06:00
MHDA- 2021/06/25 06:00
PMCR- 2022/06/30
CRDT- 2021/06/22 20:27
PHST- 2021/01/11 00:00 [received]
PHST- 2021/02/27 00:00 [accepted]
PHST- 2021/06/22 20:27 [entrez]
PHST- 2021/06/23 06:00 [pubmed]
PHST- 2021/06/25 06:00 [medline]
PHST- 2022/06/30 00:00 [pmc-release]
AID - 10.28920/dhm51.2.216-219 [doi]
PST - ppublish
SO  - Diving Hyperb Med. 2021 Jun 30;51(2):216-219. doi: 10.28920/dhm51.2.216-219.