PMID- 34177024 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20221221 IS - 0190-7409 (Print) IS - 0190-7409 (Electronic) IS - 0190-7409 (Linking) VI - 128 DP - 2021 Sep TI - Do malnutrition, pre-existing morbidities, and poor household environmental conditions aggravate susceptibility to Coronavirus disease (COVID-19)? A study on under-five children in India. PG - 105962 LID - 10.1016/j.childyouth.2021.105962 [doi] AB - BACKGROUND: The novel Coronavirus disease 2019 (2019-nCoV) outbreak, caused by severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), has become the worst serious global risk to humanity in the last century and linked with various risk factors. OBJECTIVE: To find out the risk zone associated with Coronavirus disease among children under-five age using malnourished status, pre-existing morbidity conditions, poor household environmental conditions, and also with case fatality rate (CFR) and active case rate (ACR) of COVID-19 in India. DATA SOURCES & METHODS: Data was collected from the 4th round of the National Family Health Survey (NFHS)-4, 2015-16, and CFR and ACR of COVID-19 related data collected from the Ministry of Health and Family Welfare (MoHFW) on 18th May 2020. Mean, standard deviation, and Z-score statistical methods have been employed to identify the risk factors zone and Hot Spot analysis (Getis-Ord Gi) has been done. RESULTS: The states and union territories (UTs) which have a high composite vulnerability score (CVS) of COVID-19 among under-five children are in Meghalaya (CVS = 1), Uttar Pradesh (CVS = 0.93), Jharkhand (CVS = 0.86), Bihar (CVS = 0.74), Madhya Pradesh (CVS = 0.74), and Odisha (CVS = 0.55). The states and UTs which have low composite vulnerability score of COVID-19 among under-five children are in Sikkim (CVS = -0.90), Daman & Diu (CVS = -0.76) Lakshadweep (CVS = -0.74), Kerala (CVS = -0.72), Chandigarh (CVS = -0.71). The COVID-19 high-risk zones (hot spot: 99% Confidence interval [CI]) were observed in Madhya Pradesh, Uttar Pradesh, Jharkhand, Bihar, and Meghalaya states of India, which are spatially high clustered and the low-risk zones (cold spot: 95% CI) were observed in Kerala, Mizoram states of India. CONCLUSIONS: Well-built public health measures, including rapidly searching in high focus areas and testing of COVID-19, should be performed in vulnerable regions of COVID-19. CI - (c) 2021 Elsevier Ltd. All rights reserved. FAU - Saha, Jay AU - Saha J AD - Department of Geography, University of Gour Banga (UGB), Malda 732101, West Bengal, India. FAU - Chouhan, Pradip AU - Chouhan P AD - Department of Geography, University of Gour Banga (UGB), Malda 732101, West Bengal, India. LA - eng PT - Journal Article DEP - 20210623 PL - England TA - Child Youth Serv Rev JT - Children and youth services review JID - 8110100 PMC - PMC8220865 OTO - NOTNLM OT - ACR OT - CFR OT - COVID-19 OT - Hot spot OT - India OT - Malnutrition OT - Morbidity OT - Risk factor OT - Under-five children COIS- The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2021/06/29 06:00 MHDA- 2021/06/29 06:01 PMCR- 2021/06/23 CRDT- 2021/06/28 05:46 PHST- 2020/05/21 00:00 [received] PHST- 2021/01/20 00:00 [revised] PHST- 2021/02/15 00:00 [accepted] PHST- 2021/06/29 06:00 [pubmed] PHST- 2021/06/29 06:01 [medline] PHST- 2021/06/28 05:46 [entrez] PHST- 2021/06/23 00:00 [pmc-release] AID - S0190-7409(21)00041-4 [pii] AID - 105962 [pii] AID - 10.1016/j.childyouth.2021.105962 [doi] PST - ppublish SO - Child Youth Serv Rev. 2021 Sep;128:105962. doi: 10.1016/j.childyouth.2021.105962. Epub 2021 Jun 23.