PMID- 34179505
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210629
IS  - 2391-5463 (Print)
IS  - 2391-5463 (Electronic)
VI  - 16
IP  - 1
DP  - 2021
TI  - Mediastinal mixed germ cell tumor: A case report and literature review.
PG  - 892-898
LID - 10.1515/med-2021-0293 [doi]
AB  - Mixed germ cell tumor (MGCT) mainly occurs in young women's ovaries and men's 
      testicles and rarely occurs outside the gonad. Fewer than 10 cases of mediastinal 
      MGCT are available in PubMed, Embase, and other databases in English, while 
      mediastinal MGCT with three pathological components, such as yolk sac tumor, 
      immature teratoma, and embryonal carcinoma, has not been reported previously. A 
      12-year-old male sought medical attention for chest discomfort and underwent a 
      computed tomography (CT) scan. A large soft tissue mass occupying most of the 
      left thoracic cavity and mediastinum was detected. A CT-guided biopsy was 
      performed, and an MGCT was diagnosed with pathological components, including yolk 
      sac tumor, immature teratoma, and a small amount of embryonal carcinoma. Due to 
      the large size of the tumor, the patient was treated with an EP regimen 
      (etoposide + cisplatin) and paclitaxel + ifosfamide + cisplatin interstitial 
      chemotherapy. The patient was followed up for 6 months and was alive with the 
      disease. To the best of our knowledge, this is the 10th patient with MGCT in the 
      mediastinum. The incidence of mediastinal MGCT is low, but it should still be 
      considered one of the differential diagnoses of isolated pleural fibroma and 
      neurogenic tumors.
CI  - (c) 2021 Xianwen Hu et al., published by De Gruyter.
FAU - Hu, Xianwen
AU  - Hu X
AD  - Department of Nuclear Medicine, Affiliated Hospital of Zunyi Medical University, 
      Zunyi 563003, Guizhou Province, People's Republic of China.
AD  - Department of Radiology, Weng'an Qingzhu Hospital, Weng'an 550400, Guizhou, 
      People's Republic of China.
FAU - Li, Dandan
AU  - Li D
AD  - Department of Obstetrics, Zunyi Hospital of Traditional Chinese Medicine, Zunyi 
      563003, Guizhou, People's Republic of China.
FAU - Xia, Jinhua
AU  - Xia J
AD  - Department of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi 
      563003, Guizhou, People's Republic of China.
FAU - Wang, Pan
AU  - Wang P
AD  - Department of Nuclear Medicine, Affiliated Hospital of Zunyi Medical University, 
      Zunyi 563003, Guizhou Province, People's Republic of China.
FAU - Cai, Jiong
AU  - Cai J
AD  - Department of Nuclear Medicine, Affiliated Hospital of Zunyi Medical University, 
      Zunyi 563003, Guizhou Province, People's Republic of China.
LA  - eng
PT  - Case Reports
DEP - 20210618
PL  - Poland
TA  - Open Med (Wars)
JT  - Open medicine (Warsaw, Poland)
JID - 101672167
PMC - PMC8216226
OTO - NOTNLM
OT  - case report
OT  - computed tomography
OT  - mediastinal
OT  - mixed germ cell tumor
COIS- Conflict of interest: The authors declare no conflict of interest.
EDAT- 2021/06/29 06:00
MHDA- 2021/06/29 06:01
PMCR- 2021/06/18
CRDT- 2021/06/28 06:09
PHST- 2021/02/05 00:00 [received]
PHST- 2021/03/08 00:00 [revised]
PHST- 2021/04/08 00:00 [accepted]
PHST- 2021/06/28 06:09 [entrez]
PHST- 2021/06/29 06:00 [pubmed]
PHST- 2021/06/29 06:01 [medline]
PHST- 2021/06/18 00:00 [pmc-release]
AID - med-2021-0293 [pii]
AID - 10.1515/med-2021-0293 [doi]
PST - epublish
SO  - Open Med (Wars). 2021 Jun 18;16(1):892-898. doi: 10.1515/med-2021-0293. 
      eCollection 2021.