PMID- 34196229
OWN - NLM
STAT- Publisher
LR  - 20240222
IS  - 1541-3527 (Electronic)
IS  - 0091-2174 (Linking)
DP  - 2021 Jul 1
TI  - Medication adherence in bipolar disorder: Exploring the role of predominant 
      polarity.
PG  - 912174211030163
LID - 10.1177/00912174211030163 [doi]
AB  - OBJECTIVES: Medication non-adherence is one important reason behind sub-optimal 
      outcome from treatment of bipolar affective disorder (BPAD). Though various 
      reasons behind medication non-adherence have been identified, little is known 
      about the medication adherence patterns across various predominant polarities 
      (PP) in BPAD. METHODS: 100 euthymic patients of BPAD were purposively recruited 
      and the PP were determined. Subsequently, Morisky Medication adherence scale 
      (MMAS); Global Assessment of Functioning (GAF); Oslo Social Support Scale and 
      World Health Organization Quality of Life scale- Brief version (WHOQOL-Bref) were 
      administered. Analysis of covariance (ANCOVA) was done to estimate the difference 
      of scores of MMAS after adjusting for any potential confounders. RESULTS: 
      Overall, 44 patients with manic PP (MPP), 17 with depressive PP (DPP) and 39 with 
      indeterminate PP (IPP) were recruited. It was found that patients who presented 
      with DPP showed significantly higher medication adherence as compared to MPP. 
      CONCLUSION: Knowledge of PP of a patient of BPAD can be useful in anticipating 
      medication adherence and treatment outcome. The major limitations included 
      non-probability sampling, cross-sectional design and limited generalizability of 
      the results.
FAU - Ghosal, Sutanuka
AU  - Ghosal S
AD  - Department of Psychiatry, Institute of Post-Graduate Medical Education & 
      Research, Kolkata, India.
FAU - Mallik, Nitu
AU  - Mallik N
AD  - Department of Psychiatry, College of Medicine & JNM Hospital, Kalyani, India.
FAU - Acharya, Rudraprasad
AU  - Acharya R
AD  - Department of Psychiatry, Medical College and Hospital, Kolkata, India.
FAU - Dasgupta, Gargi
AU  - Dasgupta G
AD  - Department of Psychiatry, Medical College and Hospital, Kolkata, India.
FAU - Mondal, Dilip Kumar
AU  - Mondal DK
AD  - Department of Psychiatry, R. G. Kar Medical College and Hospital, Kolkata, India.
FAU - Pal, Arghya
AU  - Pal A
AUID- ORCID: 0000-0002-5887-1971
AD  - Department of Psychiatry, All India Institute of Medical Sciences, Raebareli, 
      India.
LA  - eng
PT  - Journal Article
DEP - 20210701
PL  - United States
TA  - Int J Psychiatry Med
JT  - International journal of psychiatry in medicine
JID - 0365646
SB  - IM
OTO - NOTNLM
OT  - bipolar disorder
OT  - compliance
OT  - euthymia
OT  - medication adherence
OT  - predominant polarity
EDAT- 2021/07/02 06:00
MHDA- 2021/07/02 06:00
CRDT- 2021/07/01 08:38
PHST- 2021/07/01 08:38 [entrez]
PHST- 2021/07/02 06:00 [pubmed]
PHST- 2021/07/02 06:00 [medline]
AID - 10.1177/00912174211030163 [doi]
PST - aheadofprint
SO  - Int J Psychiatry Med. 2021 Jul 1:912174211030163. doi: 10.1177/00912174211030163.