PMID- 34200569
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240402
IS  - 2076-2615 (Print)
IS  - 2076-2615 (Electronic)
IS  - 2076-2615 (Linking)
VI  - 11
IP  - 6
DP  - 2021 Jun 10
TI  - Influence of the Chelation Process on the Stability of Organic Trace Mineral 
      Supplements Used in Animal Nutrition.
LID - 10.3390/ani11061730 [doi]
LID - 1730
AB  - The effect of the chelation process on the pH-dependent stability of organic 
      trace minerals (OTMs) used as mineral supplements in animal nutrition was 
      assessed using analytical techniques such as potentiometry, Fourier Transform 
      Infrared Spectroscopy (FTIRS) and amino acid profiling. The aim was to understand 
      the influence and relative importance of the manufacturing conditions on mineral 
      chelation and the subsequent pH stability of OTMs. A selection of OTMs were 
      assessed over a wide pH range to account for the typical environmental changes 
      encountered in the gastrointestinal (GI) tract. In the case of proteinate type 
      products, the potentiometric assessment of free mineral concentration indicated 
      that the hydrolysis procedure used to generate the chelating peptides was the 
      major influencer of the pH stability of the products. Many products are available 
      under the umbrella term "OTMs", including amino acid complexes, amino acid 
      chelates, polysaccharide complexes and proteinates. Significant differences in 
      the pH-dependent stability of a range of commercially available OTMs were 
      observed.
FAU - Byrne, Laurann
AU  - Byrne L
AUID- ORCID: 0000-0002-6691-1590
AD  - Alltech Bioscience Centre, Summerhill Road, Dunboyne, A86 X006 Co. Meath, 
      Ireland.
FAU - Hynes, Michael J
AU  - Hynes MJ
AD  - School of Chemistry, National University of Ireland, H91 TK33 Galway, Ireland.
FAU - Connolly, Cathal D
AU  - Connolly CD
AD  - Alltech Bioscience Centre, Summerhill Road, Dunboyne, A86 X006 Co. Meath, 
      Ireland.
FAU - Murphy, Richard A
AU  - Murphy RA
AUID- ORCID: 0000-0002-4143-7431
AD  - Alltech Bioscience Centre, Summerhill Road, Dunboyne, A86 X006 Co. Meath, 
      Ireland.
LA  - eng
PT  - Journal Article
DEP - 20210610
PL  - Switzerland
TA  - Animals (Basel)
JT  - Animals : an open access journal from MDPI
JID - 101635614
PMC - PMC8227544
OTO - NOTNLM
OT  - acidic stability
OT  - enzyme hydrolysis
OT  - mineral absorption
OT  - organic trace minerals (OTMs)
OT  - proteinates
COIS- L.B., C.C. and R.M. are employed by Alltech Inc., a manufacture of OTMs. M.J.H. 
      has been involved as an external consultant for Alltech Inc.
EDAT- 2021/07/03 06:00
MHDA- 2021/07/03 06:01
PMCR- 2021/06/10
CRDT- 2021/07/02 01:08
PHST- 2021/04/22 00:00 [received]
PHST- 2021/06/02 00:00 [revised]
PHST- 2021/06/08 00:00 [accepted]
PHST- 2021/07/02 01:08 [entrez]
PHST- 2021/07/03 06:00 [pubmed]
PHST- 2021/07/03 06:01 [medline]
PHST- 2021/06/10 00:00 [pmc-release]
AID - ani11061730 [pii]
AID - animals-11-01730 [pii]
AID - 10.3390/ani11061730 [doi]
PST - epublish
SO  - Animals (Basel). 2021 Jun 10;11(6):1730. doi: 10.3390/ani11061730.