PMID- 34202635
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210726
IS  - 2075-4418 (Print)
IS  - 2075-4418 (Electronic)
IS  - 2075-4418 (Linking)
VI  - 11
IP  - 7
DP  - 2021 Jun 24
TI  - Microperimetry-Assessed Functional Alterations and OCT-Changes in Patients after 
      Retinal Detachment Surgery Using Pars Plana Vitrectomy and SF6 Tamponade.
LID - 10.3390/diagnostics11071157 [doi]
LID - 1157
AB  - BACKGROUND: We study the retinal function measured by macular integrity 
      assessment microperimetry (MAIA) and structural changes assessed by scanning 
      swept source optical coherence tomography (SS-OCT) between healthy individuals 
      and patients undergoing pars plana vitrectomy (PPV) after rhegmatogenous retinal 
      detachment (RRD). METHODS: Cross-sectional study. Early Treatment Diabetic 
      Retinopathy Study (ETDRS) grids were measured by SS-OCT and compared with the 
      MAIA parameters. RESULTS: Thirty-eight eyes with RRD (19 macula-on and 19 
      macula-off) were compared with 113 healthy eyes. The retinal sensitivity and 
      average total threshold were reduced in all sectors in the RRD group; macular 
      integrity index was increased. Macular thicknesses in total retina and ganglion 
      cell layer (GCL)++ protocols were higher in the RRD group in nasal outer (NO) and 
      central (C) sectors and only in C sector for GCL+ protocol. Thicknesses were 
      lower in total retina, GCL++ protocols in the temporal outer (TO) sector and in 
      the GCL+ protocol in NO sector. Best-corrected visual acuity (BCVA) correlated 
      moderately with retinal sensitivity in all sectors and in just several sectors 
      with time between the date of surgery and the test. The central nasal (CN) sector 
      thickness and the average total threshold were higher in the macula-on subgroup. 
      CONCLUSIONS: RRD and subsequent surgery results in functional and structural 
      changes, especially in individuals with macular detachment.
FAU - Diaz-Barreda, Maria D
AU  - Diaz-Barreda MD
AUID- ORCID: 0000-0002-6134-0629
AD  - Department of Ophthalmology, Lozano Blesa University Hospital, 50009 Zaragoza, 
      Spain.
AD  - Aragon Health Research Institute (IIS Aragon), 50009 Zaragoza, Spain.
AD  - Department of Surgery, School of Medicine, University of Zaragoza, 50009 
      Zaragoza, Spain.
FAU - Bartolome-Sese, Isabel
AU  - Bartolome-Sese I
AD  - Department of Ophthalmology, Lozano Blesa University Hospital, 50009 Zaragoza, 
      Spain.
AD  - Aragon Health Research Institute (IIS Aragon), 50009 Zaragoza, Spain.
AD  - Department of Surgery, School of Medicine, University of Zaragoza, 50009 
      Zaragoza, Spain.
FAU - Boned-Murillo, Ana
AU  - Boned-Murillo A
AD  - Department of Ophthalmology, Lozano Blesa University Hospital, 50009 Zaragoza, 
      Spain.
AD  - Aragon Health Research Institute (IIS Aragon), 50009 Zaragoza, Spain.
AD  - Department of Surgery, School of Medicine, University of Zaragoza, 50009 
      Zaragoza, Spain.
FAU - Ferreras, Antonio
AU  - Ferreras A
AUID- ORCID: 0000-0002-2914-2593
AD  - Aragon Health Research Institute (IIS Aragon), 50009 Zaragoza, Spain.
AD  - Department of Surgery, School of Medicine, University of Zaragoza, 50009 
      Zaragoza, Spain.
AD  - Department of Ophthalmology, Miguel Servet University Hospital, 50009 Zaragoza, 
      Spain.
FAU - Orduna-Hospital, Elvira
AU  - Orduna-Hospital E
AUID- ORCID: 0000-0003-2710-1875
AD  - Aragon Health Research Institute (IIS Aragon), 50009 Zaragoza, Spain.
AD  - Department of Applied Physics, University of Zaragoza, 50009 Zaragoza, Spain.
FAU - Ascaso, Francisco J
AU  - Ascaso FJ
AD  - Department of Ophthalmology, Lozano Blesa University Hospital, 50009 Zaragoza, 
      Spain.
AD  - Aragon Health Research Institute (IIS Aragon), 50009 Zaragoza, Spain.
AD  - Department of Surgery, School of Medicine, University of Zaragoza, 50009 
      Zaragoza, Spain.
FAU - Pinilla, Isabel
AU  - Pinilla I
AUID- ORCID: 0000-0003-0349-9997
AD  - Department of Ophthalmology, Lozano Blesa University Hospital, 50009 Zaragoza, 
      Spain.
AD  - Aragon Health Research Institute (IIS Aragon), 50009 Zaragoza, Spain.
AD  - Department of Surgery, School of Medicine, University of Zaragoza, 50009 
      Zaragoza, Spain.
LA  - eng
PT  - Journal Article
DEP - 20210624
PL  - Switzerland
TA  - Diagnostics (Basel)
JT  - Diagnostics (Basel, Switzerland)
JID - 101658402
PMC - PMC8304304
OTO - NOTNLM
OT  - microperimetry
OT  - optical coherence tomography
OT  - retinal thickness
OT  - rhegmatogenous retinal detachment
OT  - swept source OCT
COIS- The authors declare no conflict of interest.
EDAT- 2021/07/03 06:00
MHDA- 2021/07/03 06:01
PMCR- 2021/06/24
CRDT- 2021/07/02 01:14
PHST- 2021/05/18 00:00 [received]
PHST- 2021/06/11 00:00 [revised]
PHST- 2021/06/21 00:00 [accepted]
PHST- 2021/07/02 01:14 [entrez]
PHST- 2021/07/03 06:00 [pubmed]
PHST- 2021/07/03 06:01 [medline]
PHST- 2021/06/24 00:00 [pmc-release]
AID - diagnostics11071157 [pii]
AID - diagnostics-11-01157 [pii]
AID - 10.3390/diagnostics11071157 [doi]
PST - epublish
SO  - Diagnostics (Basel). 2021 Jun 24;11(7):1157. doi: 10.3390/diagnostics11071157.