PMID- 34208009
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210705
IS  - 2075-1729 (Print)
IS  - 2075-1729 (Electronic)
IS  - 2075-1729 (Linking)
VI  - 11
IP  - 6
DP  - 2021 Jun 11
TI  - The Effectiveness of Robot- vs. Virtual Reality-Based Gait Rehabilitation: A 
      Propensity Score Matched Cohort.
LID - 10.3390/life11060548 [doi]
LID - 548
AB  - Robot assisted gait training (RAGT) and virtual reality plus treadmill training 
      (VRTT) are two technologies that can support locomotion rehabilitation in 
      children and adolescents affected by acquired brain injury (ABI). The literature 
      provides evidence of their effectiveness in this population. However, a 
      comparison between these methods is not available. This study aims at comparing 
      the effectiveness of RAGT and VRTT for the gait rehabilitation of children and 
      adolescents suffering from ABI. This is a prospective cohort study with 
      propensity score matching. Between October 2016 and September 2018, all patients 
      undergoing an intensive gait rehabilitation treatment based on RAGT or VRTT were 
      prospectively observed. To minimize selection bias associated with the study 
      design, patients who underwent RAGT or VRTT were retrospectively matched for age, 
      gender, time elapsed from injury, level of impairment, and motor impairment using 
      propensity score in a matching ratio of 1:1. Outcome measures were Gross Motor 
      Function Mesure-88 (GMFM-88), six-min walking test (6MWT), Gillette Functional 
      Assessment Questionnaire (FAQ), and three-dimensional gait analysis (GA). The FAQ 
      and the GMFM-88 had a statistically significant increase in both groups while the 
      6MWT improved in the RAGT group only. GA highlighted changes at the proximal 
      level in the RAGT group, and at the distal district in the VRTT group. Although 
      preliminary, this work suggests that RAGT and VRTT protocols foster different 
      motor improvements, thus recommending to couple the two therapies in the 
      paediatric population with ABI.
FAU - Biffi, Emilia
AU  - Biffi E
AUID- ORCID: 0000-0002-2568-9735
AD  - Scientific Institute, IRCCS "Eugenio Medea", Bosisio Parini, 23842 Lecco, Italy.
FAU - Beretta, Elena
AU  - Beretta E
AD  - Scientific Institute, IRCCS "Eugenio Medea", Bosisio Parini, 23842 Lecco, Italy.
FAU - Storm, Fabio Alexander
AU  - Storm FA
AUID- ORCID: 0000-0002-5977-8090
AD  - Scientific Institute, IRCCS "Eugenio Medea", Bosisio Parini, 23842 Lecco, Italy.
FAU - Corbetta, Claudio
AU  - Corbetta C
AD  - Scientific Institute, IRCCS "Eugenio Medea", Bosisio Parini, 23842 Lecco, Italy.
FAU - Strazzer, Sandra
AU  - Strazzer S
AD  - Scientific Institute, IRCCS "Eugenio Medea", Bosisio Parini, 23842 Lecco, Italy.
FAU - Pedrocchi, Alessandra
AU  - Pedrocchi A
AUID- ORCID: 0000-0001-9957-2786
AD  - NEARLab, Department of Electronics, Information and Bioengineering, Politecnico 
      di Milano, 20133 Milan, Italy.
FAU - Ambrosini, Emilia
AU  - Ambrosini E
AD  - NEARLab, Department of Electronics, Information and Bioengineering, Politecnico 
      di Milano, 20133 Milan, Italy.
LA  - eng
GR  - EMPATIA@Lecco/Fondazione Cariplo/
GR  - EMPATIA@Lecco/Regione Lombardia/
GR  - RC 2020/2021 to E. Biffi/Ministero della Salute/
PT  - Journal Article
DEP - 20210611
PL  - Switzerland
TA  - Life (Basel)
JT  - Life (Basel, Switzerland)
JID - 101580444
PMC - PMC8230650
OTO - NOTNLM
OT  - acquired brain injury
OT  - children
OT  - cohort study
OT  - propensity score matching
OT  - robot-assisted gait training
OT  - virtual reality plus treadmill training
COIS- The Authors declare no conflict of interest.
EDAT- 2021/07/03 06:00
MHDA- 2021/07/03 06:01
PMCR- 2021/06/11
CRDT- 2021/07/02 01:33
PHST- 2021/04/29 00:00 [received]
PHST- 2021/06/07 00:00 [revised]
PHST- 2021/06/09 00:00 [accepted]
PHST- 2021/07/02 01:33 [entrez]
PHST- 2021/07/03 06:00 [pubmed]
PHST- 2021/07/03 06:01 [medline]
PHST- 2021/06/11 00:00 [pmc-release]
AID - life11060548 [pii]
AID - life-11-00548 [pii]
AID - 10.3390/life11060548 [doi]
PST - epublish
SO  - Life (Basel). 2021 Jun 11;11(6):548. doi: 10.3390/life11060548.