PMID- 34213198
OWN - NLM
STAT- MEDLINE
DCOM- 20210726
LR  - 20210726
IS  - 1872-2059 (Electronic)
IS  - 1000-8713 (Linking)
VI  - 38
IP  - 6
DP  - 2020 Jun 8
TI  - [Simultaneous determination of five baicaleins in healthy product tablets by 
      dispersive solid-phase extraction-high performance liquid chromatography-tandem 
      mass spectrometry].
PG  - 672-678
LID - 10.3724/SP.J.1123.2019.11008 [doi]
AB  - A method based on dispersive solid-phase extraction-high performance liquid 
      chromatography-tandem mass spectrometry (DSPE-HPLC-MS/MS) was developed for the 
      simultaneous determination of five analytes scutellarein, 4'-hydroxywogonin, 
      norwogonin, baicalein, and wogonin in healthy product tablets. The samples were 
      extracted with 10 mL acetone and purified on 75 mg C(18). The types and dosages 
      of the extracted solvents and adsorbents were optimized. The results showed that 
      these five analytes exhibited good linear relationships in their respective 
      linear ranges. The correlation coefficients (r) were more than 0.99. The 
      detection limits and quantitative limits were 0.5-40 mug/kg and 2.0-120 mug/kg, 
      respectively. Recovery tests were carried out using three kinds of health product 
      tablet matrices. The concentrations were one, five, and ten times the 
      quantitative limit. The average recovery of these five targets was 83.1% to 
      106.5%, with relative standard deviations (RSDs) ranging from 0.97% to 4.52%. 
      This method is easy to operate, and it shows high sensitivity and good 
      reproducibility. Thus, it is suitable for the simultaneous determination of the 
      target compounds in health tablets.
FAU - Cen, Jianbin
AU  - Cen J
AD  - Guangzhou Inspection and Testing Certification Group Company Limited, National 
      Quality Testing Center for Processed Food, Guangzhou 511447, China.
FAU - Liang, Zhisen
AU  - Liang Z
AD  - Guangzhou Inspection and Testing Certification Group Company Limited, National 
      Quality Testing Center for Processed Food, Guangzhou 511447, China.
FAU - Ou, Shuojun
AU  - Ou S
AD  - Guangzhou Inspection and Testing Certification Group Company Limited, National 
      Quality Testing Center for Processed Food, Guangzhou 511447, China.
FAU - Huang, Jiale
AU  - Huang J
AD  - Guangzhou Inspection and Testing Certification Group Company Limited, National 
      Quality Testing Center for Processed Food, Guangzhou 511447, China.
FAU - Li, Xiuying
AU  - Li X
AD  - Guangzhou Inspection and Testing Certification Group Company Limited, National 
      Quality Testing Center for Processed Food, Guangzhou 511447, China.
FAU - Lin, Qinglan
AU  - Lin Q
AD  - Guangzhou Inspection and Testing Certification Group Company Limited, National 
      Quality Testing Center for Processed Food, Guangzhou 511447, China.
FAU - Chen, Yuzhen
AU  - Chen Y
AD  - Guangzhou Inspection and Testing Certification Group Company Limited, National 
      Quality Testing Center for Processed Food, Guangzhou 511447, China.
FAU - Liu, Xinjie
AU  - Liu X
AD  - Guangzhou Inspection and Testing Certification Group Company Limited, National 
      Quality Testing Center for Processed Food, Guangzhou 511447, China.
FAU - Lin, Senyu
AU  - Lin S
AD  - Guangzhou Inspection and Testing Certification Group Company Limited, National 
      Quality Testing Center for Processed Food, Guangzhou 511447, China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Flavanones)
RN  - 0 (Tablets)
RN  - 49QAH60606 (baicalein)
SB  - IM
MH  - Chromatography, High Pressure Liquid
MH  - Flavanones/*analysis
MH  - Limit of Detection
MH  - Reproducibility of Results
MH  - Solid Phase Extraction
MH  - Tablets/analysis
MH  - Tandem Mass Spectrometry
OTO - NOTNLM
OT  - baicalein
OT  - dispersive solid-phase extraction (DSPE)
OT  - health product
OT  - high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)
EDAT- 2021/07/03 06:00
MHDA- 2021/07/27 06:00
CRDT- 2021/07/02 09:12
PHST- 2021/07/02 09:12 [entrez]
PHST- 2021/07/03 06:00 [pubmed]
PHST- 2021/07/27 06:00 [medline]
AID - 10.3724/SP.J.1123.2019.11008 [doi]
PST - ppublish
SO  - Se Pu. 2020 Jun 8;38(6):672-678. doi: 10.3724/SP.J.1123.2019.11008.