PMID- 34221278
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220424
IS  - 2008-6164 (Print)
IS  - 2008-6172 (Electronic)
IS  - 2008-6164 (Linking)
VI  - 12
IP  - 3
DP  - 2021 Apr
TI  - Added diagnostic value of SPECT to evaluate bone metastases in breast cancer 
      patients with normal whole body bone scan.
PG  - 290-293
LID - 10.22088/cjim.12.3.290 [doi]
AB  - BACKGROUND: In this research, we aimed to survey the added value of single photon 
      emission computed tomography (SPECT) in comparison with planar whole body bone 
      scan to visualize bone metastatic lesions in patients with breast cancer. 
      METHODS: A total of 80 patients with breast cancer (invasive ductal carcinoma) 
      were examined with planar whole body bone scan and SPECT imaging using 
      99mTc-labelled methylene diphosphonate (99mTc-MDP). The patients with abnormal 
      uptakes in SPECT imaging were also investigated with magnetic resonance imaging 
      (MRI). RESULTS: Among these 80 patients with normal whole body bone SPECT scan, 
      19 (23.25%) of them revealed abnormal 99mTc-MDP uptake in skeleton. Furthermore, 
      these 19 patients were subjected to MRI and 3 (3.75%) of them were confirmed with 
      metastatic bone lesion. CONCLUSION: The obtained data suggest that SPECT possess 
      the added diagnostic over planar whole body bone scan.
CI  - Copyright (c) 2020, Babol University of Medical Sciences.
FAU - Abedi, Seyed Mohammad
AU  - Abedi SM
AD  - Department of Radiology and Nuclear Medicine , Faculty of Medicine, 
      Cardiovascular Research Center, Mazandaran University of Medical Sciences, Sari, 
      Iran.
FAU - Mardanshahi, Alireza
AU  - Mardanshahi A
AD  - Department of Radiology and Nuclear Medicine , Faculty of Medicine, 
      Cardiovascular Research Center, Mazandaran University of Medical Sciences, Sari, 
      Iran.
FAU - Zeanali, Reza
AU  - Zeanali R
AD  - Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
LA  - eng
PT  - Journal Article
PL  - Iran
TA  - Caspian J Intern Med
JT  - Caspian journal of internal medicine
JID - 101523876
PMC - PMC8223046
OTO - NOTNLM
OT  - 99mTc-MDP
OT  - Bone metastasis
OT  - Breast cancer
OT  - SPECT
OT  - Whole body bone scan
EDAT- 2021/07/06 06:00
MHDA- 2021/07/06 06:01
PMCR- 2021/04/01
CRDT- 2021/07/05 10:05
PHST- 2021/07/05 10:05 [entrez]
PHST- 2021/07/06 06:00 [pubmed]
PHST- 2021/07/06 06:01 [medline]
PHST- 2021/04/01 00:00 [pmc-release]
AID - 10.22088/cjim.12.3.290 [doi]
PST - ppublish
SO  - Caspian J Intern Med. 2021 Apr;12(3):290-293. doi: 10.22088/cjim.12.3.290.