PMID- 34223349 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210706 IS - 2666-5204 (Electronic) IS - 2666-5204 (Linking) VI - 5 DP - 2021 Mar TI - A review of ECMO for cardiac arrest. PG - 100083 LID - 10.1016/j.resplu.2021.100083 [doi] LID - 100083 AB - Cardiac arrest is an important public health concern, affecting an estimated 356,500 people in the out-of-hospital setting and 209,000 people in the in-hospital setting each year. The causes of cardiac arrest include acute coronary syndromes, pulmonary embolism, dyskalemia, respiratory failure, hypovolemia, sepsis, and poisoning among many others. In order to tackle the enormous issue of high mortality among sufferers of cardiac arrest, ongoing research has been seeking improved treatment protocols and novel therapies. One of the mechanical devices that has been increasingly utilized for cardiac arrest is venoarterial extracorporeal membrane oxygenation (VA-ECMO). Presently there is only one published randomized controlled trial examining the use of VA-ECMO as part of cardiopulmonary resuscitation (CPR), a process referred to as extracorporeal cardiopulmonary resuscitation (ECPR). Recently there has been significant progress in providing ECPR for refractory cardiac arrest patients. This narrative review seeks to outline the use of ECPR for both in-hospital and out-of-hospital cardiac arrest, as well as provide information on the expected outcomes associated with its use. CI - (c) 2021 The Author(s). FAU - Klee, Tyler E AU - Klee TE AD - University of Arizona College of Medicine, Tucson, AZ, United States. FAU - Kern, Karl B AU - Kern KB AD - University of Arizona College of Medicine, Tucson, AZ, United States. AD - University of Arizona Sarver Heart Center, Tucson, AZ, United States. LA - eng PT - Journal Article PT - Review DEP - 20210206 PL - Netherlands TA - Resusc Plus JT - Resuscitation plus JID - 101774410 PMC - PMC8244483 OTO - NOTNLM OT - COVID-19 OT - Cardiac arrest OT - ECMO OT - ECPR OT - Extracorporeal cardiopulmonary resuscitation OT - Extracorporeal membrane oxygenation EDAT- 2021/07/06 06:00 MHDA- 2021/07/06 06:01 PMCR- 2021/02/06 CRDT- 2021/07/05 10:24 PHST- 2020/11/12 00:00 [received] PHST- 2021/01/07 00:00 [revised] PHST- 2021/01/12 00:00 [accepted] PHST- 2021/07/05 10:24 [entrez] PHST- 2021/07/06 06:00 [pubmed] PHST- 2021/07/06 06:01 [medline] PHST- 2021/02/06 00:00 [pmc-release] AID - S2666-5204(21)00008-4 [pii] AID - 100083 [pii] AID - 10.1016/j.resplu.2021.100083 [doi] PST - epublish SO - Resusc Plus. 2021 Feb 6;5:100083. doi: 10.1016/j.resplu.2021.100083. eCollection 2021 Mar.