PMID- 34224233
OWN - NLM
STAT- MEDLINE
DCOM- 20211213
LR  - 20220424
IS  - 1578-1267 (Electronic)
IS  - 0301-0546 (Linking)
VI  - 49
IP  - 4
DP  - 2021
TI  - Mite avoidance decreased mite-specific IgE levels and ameliorated asthma symptoms 
      in subjects who lived in temporary housing after natural disasters.
PG  - 171-179
LID - 10.15586/aei.v49i4.240 [doi]
AB  - BACKGROUND: We previously reported an increased prevalence of asthma among 
      patients who had lived in temporary housing after the 2011 Great East Japan 
      Earthquake. We investigated the prognosis of asthma in former residents of 
      temporary housing after allergen avoidance. METHODS: Asthma was diagnosed in 
      adults >/= 15 years from 2014 to 2019 who had lived in temporary housing in 
      Ishinomaki City for at least 1 year. The disease prognosis after the intervention 
      of allergen avoidance in cases that were followed for more than 3 years during 
      the 6-year study period was analyzed. We measured the Dermatophagoides farinae 
      -specific immunoglobulin E (IgE) levels in serum, and the amount of 
      Dermatophagoides group 1 (Der 1) antigen on their futons or mattresses. We 
      instructed residents in an allergen avoidance strategy that included 32 tasks, 
      including using microfiber bedding covers. RESULTS: Of the 202 examinees who were 
      followed for at least 3 years during the 6-year study period, 72(35.6%) were 
      asthmatic during at least one examination. Of these 72 asthmatics, 55(76.4%) 
      developed the disease after the earthquake, and more than half of the cases that 
      we diagnosed at the examination were mild intermittent asthma. After the 
      allergen-avoidance intervention, both the Der 1 level on the futons or mattresses 
      of residents who were diagnosed with asthma but who were nonasthmatic at the 
      final screening and their serum Der f-specific IgE levels significantly decreased 
      (P < 0.01) at the final examination. CONCLUSION: Antigen avoidance ameliorated 
      mild asthma that was prevalent among residents of temporary housing after the 
      earthquake.
FAU - Chiyako, Oshikata
AU  - Chiyako O
AD  - Department of Allergy and Respirology, Hiratsuka City Hospital, Hiratsuka, Japan.
AD  - Department of Pulmonology, Yokohama City University Graduate School of Medicine, 
      Kanazawa-ku, Japan.
FAU - Maiko, Watanabe
AU  - Maiko W
AD  - Division of Microbiology, National Institute of Health Sciences, Kawasaki-ku, 
      Japan.
FAU - Masatsugu, Ishida
AU  - Masatsugu I
AD  - Department of Respiratory Medicine, Japanese Red Cross Ishinomaki Hospital, 
      Ishinomaki, Japan.
FAU - Seiichi, Kobayashi
AU  - Seiichi K
AD  - Department of Respiratory Medicine, Japanese Red Cross Ishinomaki Hospital, 
      Ishinomaki, Japan.
FAU - Kazuhiro, Hashimoto
AU  - Kazuhiro H
AD  - FCG Research Institute, Inc., Tokyo, Japan.
FAU - Naoki, Kobayashi
AU  - Naoki K
AD  - School of Life and Environmental Sciences, Azabu University, Sagamihara, Japan.
FAU - Akiko, Yamazaki
AU  - Akiko Y
AD  - Co-Department of Veterinary Medicine, Iwate University, Morioka, Japan.
FAU - Rumi, Konuma
AU  - Rumi K
AD  - Tokyo Metropolitan Industrial Technology Research Institute, Tokyo, Japan 
      135-0064.
FAU - Takashi, Shimada
AU  - Takashi S
AD  - Nichinichi Pharmaceutical Co. Ltd., Iga, Japan.
FAU - Takeshi, Kaneko
AU  - Takeshi K
AD  - Department of Pulmonology, Yokohama City University Graduate School of Medicine, 
      Kanazawa-ku, Japan.
FAU - Yoichi, Kamata
AU  - Yoichi K
AD  - Faculty of Life Science, Senri Kinran University, Suita, Japan.
FAU - Shinichi, Kuriyama
AU  - Shinichi K
AD  - Tohoku University Graduate School of Medicine, Sendai, Japan.
AD  - Tohoku University International Research Institute of Disaster Science, Sendai, 
      Japan.
FAU - Masaru, Yanai
AU  - Masaru Y
AD  - Department of Respiratory Medicine, Japanese Red Cross Ishinomaki Hospital, 
      Ishinomaki, Japan.
FAU - Naomi, Tsurikisawa
AU  - Naomi T
AD  - Department of Allergy and Respirology, Hiratsuka City Hospital, Hiratsuka, Japan.
AD  - Department of Pulmonology, Yokohama City University Graduate School of Medicine, 
      Kanazawa-ku, Japan; User831328@aol.com.
LA  - eng
PT  - Journal Article
DEP - 20210701
PL  - Singapore
TA  - Allergol Immunopathol (Madr)
JT  - Allergologia et immunopathologia
JID - 0370073
RN  - 0 (Allergens)
RN  - 0 (Antigens, Dermatophagoides)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Allergens
MH  - Animals
MH  - Antigens, Dermatophagoides
MH  - *Asthma/epidemiology
MH  - Housing
MH  - Humans
MH  - Immunoglobulin E
MH  - *Mites/immunology
MH  - *Natural Disasters
OTO - NOTNLM
OT  - Adult asthma
OT  - Aspergillus
OT  - Dermatophagoides farinae
OT  - Great East Japan Earthquake in 2011.3.11
OT  - allergen avoidance
OT  - mite-specific IgE
OT  - temporary housing
COIS- No potential conflict of interest was reported by the authors.
EDAT- 2021/07/06 06:00
MHDA- 2021/12/15 06:00
CRDT- 2021/07/05 12:34
PHST- 2021/02/22 00:00 [received]
PHST- 2021/04/08 00:00 [accepted]
PHST- 2021/07/05 12:34 [entrez]
PHST- 2021/07/06 06:00 [pubmed]
PHST- 2021/12/15 06:00 [medline]
AID - 10.15586/aei.v49i4.240 [doi]
PST - epublish
SO  - Allergol Immunopathol (Madr). 2021 Jul 1;49(4):171-179. doi: 
      10.15586/aei.v49i4.240. eCollection 2021.