PMID- 34224384 OWN - NLM STAT- MEDLINE DCOM- 20211015 LR - 20211015 IS - 1557-2501 (Electronic) IS - 1042-3931 (Linking) VI - 33 IP - 7 DP - 2021 Jul TI - Implementation of a High-Sensitivity Troponin-I Assay in an Academic Medical Center: A Qualitative and Quantitative Assessment. PG - E549-E556 AB - OBJECTIVES: To describe the clinical impact and lessons learned through implementation of a high sensitivity troponin (hsTn) assay. BACKGROUND: hsTn assays have received regulatory approval for use in the United States, and healthcare facilities are beginning to adopt these new assays. Questions remain about how to implement them and what effect they may have on demand for cardiovascular services. METHODS: We conducted a mixed-methods implementation science-based investigation of hsTn adoption at a single academic medical center. We designed the investigation based on the Consolidated Framework for Implementation Research, exploring clinicians' perspectives on intervention characteristics, inner setting, individual characteristics, and process of implementation domains. Focus groups were conducted with clinicians from multiple service lines. RESULTS: Participants reported that the new hsTn assay did not fundamentally change processes of care such as cardiology consultations or inpatient admissions. Implementation was facilitated by leveraging the electronic medical record to provide useful suggestions for hsTn management at the point-of-care. The use of case-based teaching was considered most effective. Areas of ongoing concern included management of high-risk patients, outpatient follow-up, and feasibility of accelerated diagnostic protocols for early discharge from the emergency department. A decrease in the number of hsTn assays ordered was observed; no change was noted for admissions, cardiology consultations, or noninvasive cardiac imaging. CONCLUSIONS: A comprehensive educational campaign, based on multidisciplinary collaboration can effectively prepare clinicians for implementation of hsTn. New hsTn assays may not have any substantial effect on acute management of patients with cardiac complaints. FAU - Winchester, David E AU - Winchester DE AD - Malcom Randall VAMC, 1601 SW Archer Rd Box 111-D, Gainesville, FL 32608 USA. david.winchester@va.gov. FAU - Betageri, Omkar AU - Betageri O FAU - Perche, Patrick AU - Perche P FAU - Allen, Brandon AU - Allen B FAU - Theis, Ryan AU - Theis R LA - eng PT - Journal Article PL - United States TA - J Invasive Cardiol JT - The Journal of invasive cardiology JID - 8917477 RN - 0 (Biomarkers) RN - 0 (Troponin I) SB - IM MH - Academic Medical Centers MH - Biomarkers MH - *Emergency Service, Hospital MH - Hospitalization MH - Humans MH - *Troponin I OTO - NOTNLM OT - implementation science OT - qualitative research OT - troponin EDAT- 2021/07/06 06:00 MHDA- 2021/10/16 06:00 CRDT- 2021/07/05 17:12 PHST- 2021/07/05 17:12 [entrez] PHST- 2021/07/06 06:00 [pubmed] PHST- 2021/10/16 06:00 [medline] PST - ppublish SO - J Invasive Cardiol. 2021 Jul;33(7):E549-E556.