PMID- 34226905
OWN - NLM
STAT- MEDLINE
DCOM- 20210812
LR  - 20210812
IS  - 1759-9679 (Electronic)
IS  - 1759-9660 (Linking)
VI  - 13
IP  - 29
DP  - 2021 Jul 29
TI  - Fluorescence assay for the sensitive detection of fipronil based on an "on-off" 
      oxidized SWCNH/aptamer sensor.
PG  - 3282-3291
LID - 10.1039/d1ay00769f [doi]
AB  - A simple, quick, effective turn-on fluorescence assay for the determination of 
      fipronil (FIP) was built based on the yellow fluorescence of FAM-aptamer and 
      excellent quenching capability of the oxidized single-walled carbon nanohorns 
      (The oxidized SWCNHs). Oxidized SWCNHs with the great advantage of good 
      dispersibility in solution were generated by link to carboxyl group and were 
      added to a specific FAM-aptamer at an optimal concentration to form an "on-off" 
      oxidized SWCNH/FAM-aptamer fluorescent sensor. The structures of the oxidized 
      SWCNHs were verified, and the comprehensive properties were evaluated by 
      characterization techniques. This paper has exploited oxidized SWCNHs as a 
      quenching agent to detect fipronil for the first time. Under the optimized 
      conditions, the limit of detection (LOD) for fipronil was 3 nM, and the recovery 
      of fipronil varied from 88.6% to 112.7% in different real samples with relative 
      standard deviations (RSDs) not more than 5%. The developed method could be 
      successfully applied for the determination of fipronil in tap water, honey and 
      corn samples.
FAU - Zhang, Jiaxin
AU  - Zhang J
AD  - School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe 
      District, Shenyang, Liaoning Province 110016, China. longshanzhao@163.com.
FAU - Feng, Tingting
AU  - Feng T
AD  - Institute of Pharmaceutical and Food Engineering, Shanxi University of Chinese 
      Medicine, Jinzhong, Shanxi Province 030619, China.
FAU - Zhang, Jiayu
AU  - Zhang J
AD  - School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe 
      District, Shenyang, Liaoning Province 110016, China. longshanzhao@163.com.
FAU - Liang, Ning
AU  - Liang N
AD  - School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 
      Shenyang, Liaoning Province 110016, China. liangning@syphu.edu.cn.
FAU - Zhao, Longshan
AU  - Zhao L
AUID- ORCID: 0000-0001-5330-0689
AD  - School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe 
      District, Shenyang, Liaoning Province 110016, China. longshanzhao@163.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Anal Methods
JT  - Analytical methods : advancing methods and applications
JID - 101519733
RN  - 0 (Aptamers, Nucleotide)
RN  - 0 (Nanotubes, Carbon)
RN  - 0 (Pyrazoles)
RN  - QGH063955F (fipronil)
SB  - IM
MH  - *Aptamers, Nucleotide
MH  - Limit of Detection
MH  - *Nanotubes, Carbon
MH  - Pyrazoles
EDAT- 2021/07/07 06:00
MHDA- 2021/08/13 06:00
CRDT- 2021/07/06 06:39
PHST- 2021/07/07 06:00 [pubmed]
PHST- 2021/08/13 06:00 [medline]
PHST- 2021/07/06 06:39 [entrez]
AID - 10.1039/d1ay00769f [doi]
PST - ppublish
SO  - Anal Methods. 2021 Jul 29;13(29):3282-3291. doi: 10.1039/d1ay00769f.