PMID- 34226960
OWN - NLM
STAT- MEDLINE
DCOM- 20211203
LR  - 20211214
IS  - 1433-7339 (Electronic)
IS  - 0941-4355 (Linking)
VI  - 30
IP  - 1
DP  - 2022 Jan
TI  - Variability in physical function for patients living with breast cancer during a 
      12-week exercise program.
PG  - 69-76
LID - 10.1007/s00520-021-06394-4 [doi]
AB  - PURPOSE: To describe the variability during weekly performance on physical 
      function tests during a 12-week individualized exercise program for patients with 
      breast cancer and to test if the expected improvements in physical function 
      surpass the minimally clinically important difference (MCID), after accounting 
      for week-to-week variance. METHODS: Twenty-five participants, 19 years and older 
      living with breast cancer within 2 years of their initial diagnosis, were 
      recruited. Some participants were undergoing active treatment, while others 
      completed their treatment. The intervention was an individualized exercise 
      session twice a week, for 1 h each session, for a total of 12 weeks. Main 
      outcomes tested included the 6-min walk test and chair stand test. RESULTS: A 
      significant average improvement was observed in the 6MWT (p < .01) and the chair 
      stand test (p < .001) following the intervention. Individual confidence intervals 
      were wide across all testing measures with only 28% and 8% of participants 
      meeting or surpassing the MCID for the 6MWT and chair stand test, respectively. 
      CONCLUSION: Despite a significant improvement in physical function during the 
      program, the majority of patients did not reach the MCID, which could be due to 
      large variability resulting from treatment-related side effects or measurement 
      error.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, 
      part of Springer Nature.
FAU - Soucy, Courtni
AU  - Soucy C
AD  - Cardiometabolic Exercise & Lifestyle Laboratory, University of New Brunswick, 
      Fredericton, NB, Canada.
AD  - Faculty of Kinesiology, University of New Brunswick, Fredericton, NB, Canada.
FAU - Bouchard, Danielle R
AU  - Bouchard DR
AD  - Cardiometabolic Exercise & Lifestyle Laboratory, University of New Brunswick, 
      Fredericton, NB, Canada.
AD  - Faculty of Kinesiology, University of New Brunswick, Fredericton, NB, Canada.
FAU - Hrubeniuk, Travis
AU  - Hrubeniuk T
AD  - Cardiometabolic Exercise & Lifestyle Laboratory, University of New Brunswick, 
      Fredericton, NB, Canada.
AD  - Interdisciplinary Studies, University of New Brunswick, Fredericton, NB, Canada.
FAU - Senechal, Martin
AU  - Senechal M
AUID- ORCID: 0000-0001-5290-6072
AD  - Cardiometabolic Exercise & Lifestyle Laboratory, University of New Brunswick, 
      Fredericton, NB, Canada. msenecha@unb.ca.
AD  - Faculty of Kinesiology, University of New Brunswick, Fredericton, NB, Canada. 
      msenecha@unb.ca.
LA  - eng
PT  - Journal Article
DEP - 20210706
PL  - Germany
TA  - Support Care Cancer
JT  - Supportive care in cancer : official journal of the Multinational Association of 
      Supportive Care in Cancer
JID - 9302957
SB  - IM
MH  - *Breast Neoplasms/therapy
MH  - Exercise
MH  - Exercise Therapy
MH  - Female
MH  - Humans
OTO - NOTNLM
OT  - Chronic disease
OT  - Exercise
OT  - Exercise performance
OT  - Functional performance
EDAT- 2021/07/07 06:00
MHDA- 2021/12/15 06:00
CRDT- 2021/07/06 06:41
PHST- 2021/02/18 00:00 [received]
PHST- 2021/06/23 00:00 [accepted]
PHST- 2021/07/07 06:00 [pubmed]
PHST- 2021/12/15 06:00 [medline]
PHST- 2021/07/06 06:41 [entrez]
AID - 10.1007/s00520-021-06394-4 [pii]
AID - 10.1007/s00520-021-06394-4 [doi]
PST - ppublish
SO  - Support Care Cancer. 2022 Jan;30(1):69-76. doi: 10.1007/s00520-021-06394-4. Epub 
      2021 Jul 6.