PMID- 34229621 OWN - NLM STAT- MEDLINE DCOM- 20210709 LR - 20221207 IS - 1471-2458 (Electronic) IS - 1471-2458 (Linking) VI - 21 IP - 1 DP - 2021 Jul 6 TI - Disparities in COVID-19 hospitalizations and mortality among black and Hispanic patients: cross-sectional analysis from the greater Houston metropolitan area. PG - 1330 LID - 10.1186/s12889-021-11431-2 [doi] LID - 1330 AB - BACKGROUND: Disparate racial/ethnic burdens of the Coronavirus Disease 2019 (COVID-19) pandemic may be attributable to higher susceptibility to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) or to factors such as differences in hospitalization and care provision. METHODS: In our cross-sectional analysis of lab-confirmed COVID-19 cases from a tertiary, eight-hospital healthcare system across greater Houston, multivariable logistic regression models were fitted to evaluate hospitalization and mortality odds for non-Hispanic Blacks (NHBs) vs. non-Hispanic Whites (NHWs) and Hispanics vs. non-Hispanics. RESULTS: Between March 3rd and July 18th, 2020, 70,496 individuals were tested for SARS-CoV-2; 12,084 (17.1%) tested positive, of whom 3536 (29.3%) were hospitalized. Among positive cases, NHBs and Hispanics were significantly younger than NHWs and Hispanics, respectively (mean age NHBs vs. NHWs: 46.0 vs. 51.7 years; p < 0.001 and Hispanic vs. non-Hispanic: 44.0 vs. 48.7 years; p < 0.001). Despite younger age, NHBs (vs. NHWs) had a higher prevalence of diabetes (25.2% vs. 17.6%; p < 0.001), hypertension (47.7% vs. 43.1%; p < 0.001), and chronic kidney disease (5.0% vs. 3.3%; p = 0.001). Both minority groups resided in lower median income (median income [USD]; NHBs vs. NHWs: 63,489 vs. 75,793; p < 0.001, Hispanic vs. non-Hispanic: 59,104 vs. 68,318; p < 0.001) and higher population density areas (median population density [per square mile]; NHBs vs. NHWs: 3257 vs. 2742; p < 0.001, Hispanic vs. non-Hispanic: 3381 vs. 2884; p < 0.001). In fully adjusted models, NHBs (vs. NHWs) and Hispanics (vs. non-Hispanic) had higher likelihoods of hospitalization, aOR (95% CI): 1.42 (1.24-1.63) and 1.61 (1.46-1.78), respectively. No differences were observed in intensive care unit (ICU) utilization or treatment parameters. Models adjusted for demographics, vital signs, laboratory parameters, hospital complications, and ICU admission vital signs demonstrated non-significantly lower likelihoods of in-hospital mortality among NHBs and Hispanic patients, aOR (95% CI): 0.65 (0.40-1.03) and 0.89 (0.59-1.31), respectively. CONCLUSIONS: Our data did not demonstrate racial and ethnic differences in care provision and hospital outcomes. Higher susceptibility of racial and ethnic minorities to SARS-CoV-2 and subsequent hospitalization may be driven primarily by social determinants. FAU - Pan, Alan P AU - Pan AP AD - Center for Outcomes Research, Houston Methodist, Josie Roberts Administration Building, 7550 Greenbriar Drive, Suite 4.123, Houston, TX, 77030, USA. FAU - Khan, Osman AU - Khan O AD - Center for Outcomes Research, Houston Methodist, Josie Roberts Administration Building, 7550 Greenbriar Drive, Suite 4.123, Houston, TX, 77030, USA. FAU - Meeks, Jennifer R AU - Meeks JR AD - Center for Outcomes Research, Houston Methodist, Josie Roberts Administration Building, 7550 Greenbriar Drive, Suite 4.123, Houston, TX, 77030, USA. FAU - Boom, Marc L AU - Boom ML AD - Department of Clinical Medicine, Houston Methodist, Houston, TX, USA. AD - Weill Cornell Medical College, New York, NY, USA. FAU - Masud, Faisal N AU - Masud FN AD - Weill Cornell Medical College, New York, NY, USA. AD - Department of Anesthesiology and Critical Care, Houston Methodist, Houston, TX, USA. FAU - Andrieni, Julia D AU - Andrieni JD AD - Department of Clinical Medicine, Houston Methodist, Houston, TX, USA. AD - Weill Cornell Medical College, New York, NY, USA. FAU - Phillips, Robert A AU - Phillips RA AD - Center for Outcomes Research, Houston Methodist, Josie Roberts Administration Building, 7550 Greenbriar Drive, Suite 4.123, Houston, TX, 77030, USA. AD - Weill Cornell Medical College, New York, NY, USA. AD - Department of Cardiology, Houston Methodist, Houston, TX, USA. FAU - Tiruneh, Yordanos M AU - Tiruneh YM AD - University of Texas Health Science Center at Tyler, Tyler, TX, USA. FAU - Kash, Bita A AU - Kash BA AD - Center for Outcomes Research, Houston Methodist, Josie Roberts Administration Building, 7550 Greenbriar Drive, Suite 4.123, Houston, TX, 77030, USA. AD - Weill Cornell Medical College, New York, NY, USA. AD - Texas A&M University School of Public Health, College Station, TX, USA. FAU - Vahidy, Farhaan S AU - Vahidy FS AUID- ORCID: 0000-0002-3464-2111 AD - Center for Outcomes Research, Houston Methodist, Josie Roberts Administration Building, 7550 Greenbriar Drive, Suite 4.123, Houston, TX, 77030, USA. fvahidy@houstonmethodist.org. AD - Houston Methodist Neurological institute, Houston Methodist, Houston, TX, USA. fvahidy@houstonmethodist.org. LA - eng PT - Journal Article DEP - 20210706 PL - England TA - BMC Public Health JT - BMC public health JID - 100968562 SB - IM MH - *Black or African American MH - *COVID-19 MH - Cross-Sectional Studies MH - Ethnicity MH - Hispanic or Latino MH - Hospitalization MH - Humans MH - SARS-CoV-2 PMC - PMC8258471 OTO - NOTNLM OT - COVID-19 OT - Disparities OT - Ethnicity OT - Race OT - SARS-CoV-2 COIS- The authors declare that they have no competing interests. EDAT- 2021/07/08 06:00 MHDA- 2021/07/10 06:00 PMCR- 2021/07/06 CRDT- 2021/07/07 05:37 PHST- 2020/10/28 00:00 [received] PHST- 2021/06/30 00:00 [accepted] PHST- 2021/07/07 05:37 [entrez] PHST- 2021/07/08 06:00 [pubmed] PHST- 2021/07/10 06:00 [medline] PHST- 2021/07/06 00:00 [pmc-release] AID - 10.1186/s12889-021-11431-2 [pii] AID - 11431 [pii] AID - 10.1186/s12889-021-11431-2 [doi] PST - epublish SO - BMC Public Health. 2021 Jul 6;21(1):1330. doi: 10.1186/s12889-021-11431-2.