PMID- 34236273
OWN - NLM
STAT- MEDLINE
DCOM- 20210818
LR  - 20220425
IS  - 1502-7708 (Electronic)
IS  - 0036-5521 (Linking)
VI  - 56
IP  - 8
DP  - 2021 Aug
TI  - EUS-guided gastroenterostomy with a lumen apposing self-expandable metallic stent 
      relieves gastric outlet obstruction - a Scandinavian case series.
PG  - 972-977
LID - 10.1080/00365521.2021.1925338 [doi]
AB  - BACKGROUND: EUS-guided gastroenterostomy (EUS-GE) with lumen-apposing metallic 
      stents (LAMS) in patients with gastric outlet obstruction (GOO) has proven to be 
      an alternative to luminal stenting in the duodenum and surgical 
      gastroenterostomy. In severely ill patients, the method can provide improved 
      quality of life (QoL) and symptom relief by restoration of the luminal passage of 
      fluid and nutrients to the small intestine. AIM: To assess the technical and 
      clinical success and safety of EUS-GE. MATERIAL AND METHODS: A dual center 
      retrospective case series of 33 consecutive patients with GOO due to malignant 
      (n = 28) or non-malignant conditions (n = 5). The patients were treated with 
      EUS-GE using cautery enhanced LAMS. Procedures were performed guided by EUS and 
      fluoroscopy in general anesthesia or conscious sedation. RESULTS: Technical 
      success was achieved in all patients. The median procedure time was 71 min and 
      the median hospital stay was three days. Thirty (91%) patients were able to 
      resume oral nutrition after the procedure. Ten patients (30%) experienced adverse 
      events (AEs), including migration of the stent, bleeding, and infection. Four 
      patients had fatal AEs (12%). All stent-related AEs were handled endoscopically. 
      Five patients (15%) needed re-intervention. The median survival time for patients 
      with malignant obstruction was 8.5 weeks (0.5-76), and 13 patients with 
      obstructing malignancies lived 12 weeks or longer. CONCLUSION: EUS-GE is a 
      minimally invasive and efficient method for restoration of the gastrointestinal 
      passage and may improve palliative care for patients with GOO. The method has 
      potential hazards and should only be offered in expert centers that regularly 
      perform the procedure.
FAU - Havre, R F
AU  - Havre RF
AD  - Department of Medicine, Haukeland University Hospital, Bergen, Norway.
AD  - Department of Clinical Medicine, University of Bergen, Bergen, Norway.
FAU - Dai, C
AU  - Dai C
AD  - Department of Medicine, Haukeland University Hospital, Bergen, Norway.
FAU - Roug, S
AU  - Roug S
AD  - Gastro Unit, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
FAU - Novovic, S
AU  - Novovic S
AD  - Gastro Unit, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
AD  - Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
FAU - Schmidt, P N
AU  - Schmidt PN
AD  - Gastro Unit, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
FAU - Feldager, E
AU  - Feldager E
AD  - Gastro Unit, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
FAU - Karstensen, J G
AU  - Karstensen JG
AD  - Gastro Unit, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
AD  - Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
FAU - Pham, K D C
AU  - Pham KDC
AD  - Department of Medicine, Haukeland University Hospital, Bergen, Norway.
AD  - Department of Clinical Medicine, University of Bergen, Bergen, Norway.
LA  - eng
PT  - Journal Article
DEP - 20210708
PL  - England
TA  - Scand J Gastroenterol
JT  - Scandinavian journal of gastroenterology
JID - 0060105
SB  - IM
MH  - Endosonography
MH  - *Gastric Outlet Obstruction/etiology/surgery
MH  - Gastroenterostomy
MH  - Humans
MH  - *Quality of Life
MH  - Retrospective Studies
MH  - Stents
MH  - Ultrasonography, Interventional
OTO - NOTNLM
OT  - Gastric outlet obstruction
OT  - endoscopic ultrasound-guided gastroenterostomy (EUS-GE)
OT  - lumen apposing metal stent (LAMS)
OT  - palliative care
EDAT- 2021/07/09 06:00
MHDA- 2021/08/19 06:00
CRDT- 2021/07/08 12:14
PHST- 2021/07/09 06:00 [pubmed]
PHST- 2021/08/19 06:00 [medline]
PHST- 2021/07/08 12:14 [entrez]
AID - 10.1080/00365521.2021.1925338 [doi]
PST - ppublish
SO  - Scand J Gastroenterol. 2021 Aug;56(8):972-977. doi: 
      10.1080/00365521.2021.1925338. Epub 2021 Jul 8.