PMID- 34237980
OWN - NLM
STAT- MEDLINE
DCOM- 20210712
LR  - 20210712
IS  - 2224-5839 (Electronic)
IS  - 2224-5820 (Linking)
VI  - 10
IP  - 6
DP  - 2021 Jun
TI  - Effects of different drugs on the curative effect, stress responses, and the 
      circulatory system of patients with hypertensive trigeminal neuralgia.
PG  - 6833-6840
LID - 10.21037/apm-21-1340 [doi]
AB  - BACKGROUND: This research aimed to analyze the effects of stellate nerve block 
      with different drugs on the curative effect, stress responses, and the 
      circulatory system of patients with hypertensive trigeminal neuralgia (TN). 
      METHODS: A retrospective analysis of 82 patients with hypertensive TN admitted to 
      our hospital from January 2019 to January 2021 was conducted, and the patients 
      were divided into a control group and an observation group according to different 
      drugs. The pain visual analogue scale (VAS) scores were determined between the 2 
      groups before treatment and at 1, 2, 3, 7, and 30 d after treatment. The mean 
      arterial pressure (MAP) and heart rate (HR) were measured in the 2 groups of 
      patients before treatment and immediately after treatment (T0), half an hour 
      after treatment (T1), 1 h after treatment (T2), and 6 h after treatment (T3). The 
      left ventricular wall thickness (LVWT), left ventricular end systolic volume 
      (LVESV), left ventricular ejection fraction (LVEF), and fraction shortening (FS) 
      were detected in the 2 groups before treatment and at T0-T2. Patient satisfaction 
      was also scored, and the incidence of adverse reactions was assessed. RESULTS: 
      The VAS scores of the 2 groups of patients decreased significantly after 
      treatment at 1, 2, 3, 7, and 30 d. The MAP and HR indicators of the 2 groups 
      decreased gradually at T0-T2, and gradually recovered to levels before treatment 
      at the T3 time point. The MAP and HR indicators of the observation group were 
      significantly lower than those of the control group at T0-T2. After treatment, 
      the levels of LVWT, LVESV, LVEF, and FS in the observation group at the T0-T2 
      time points were significantly lower than those of the control group. 
      Additionally, after treatment, the satisfaction of the observation group was 
      significantly higher than that of the control group. The total incidence of 
      adverse reactions in the observation group was significantly lower than that in 
      the control group. CONCLUSIONS: For patients with hypertensive TN, a single 
      ropivacaine stellate nerve block can significantly relieve pain, and has little 
      effect on heart function.
FAU - Lin, Tao
AU  - Lin T
AD  - Department of Anesthesiology, Sichuan Academy of Medical Sciences & Sichuan 
      Provincial People's Hospital, University of Electronic Science and Technology of 
      China, Chengdu, China.
FAU - Li, Jinfeng
AU  - Li J
AD  - Department of Anesthesiology, Chengdu Seventh People's Hospital, Chengdu, China.
FAU - Song, Junmei
AU  - Song J
AD  - Department of Cardiac Function, Sichuan Academy of Medical Sciences & Sichuan 
      Provincial People's Hospital, University of Electronic Science and Technology of 
      China, Chengdu, China.
FAU - Chen, Shiyin
AU  - Chen S
AD  - Department of Orthopedics of traditional Chinese Medicine, Sichuan Academy of 
      Medical Sciences & Sichuan Provincial People's Hospital, University of Electronic 
      Science and Technology of China, Chengdu, China.
FAU - Li, Hu
AU  - Li H
AD  - Department of Anesthesiology, Sichuan Academy of Medical Sciences & Sichuan 
      Provincial People's Hospital, University of Electronic Science and Technology of 
      China, Chengdu, China.
LA  - eng
PT  - Journal Article
PL  - China
TA  - Ann Palliat Med
JT  - Annals of palliative medicine
JID - 101585484
RN  - 0 (Pharmaceutical Preparations)
SB  - IM
MH  - *Cardiovascular System
MH  - Humans
MH  - *Pharmaceutical Preparations
MH  - Retrospective Studies
MH  - Stroke Volume
MH  - *Trigeminal Neuralgia/drug therapy
MH  - Ventricular Function, Left
OTO - NOTNLM
OT  - Stellate nerve block
OT  - hypertension
OT  - trigeminal neuralgia (TN)
EDAT- 2021/07/10 06:00
MHDA- 2021/07/13 06:00
CRDT- 2021/07/09 05:33
PHST- 2021/04/22 00:00 [received]
PHST- 2021/06/08 00:00 [accepted]
PHST- 2021/07/09 05:33 [entrez]
PHST- 2021/07/10 06:00 [pubmed]
PHST- 2021/07/13 06:00 [medline]
AID - 10.21037/apm-21-1340 [doi]
PST - ppublish
SO  - Ann Palliat Med. 2021 Jun;10(6):6833-6840. doi: 10.21037/apm-21-1340.