PMID- 34239158 OWN - NLM STAT- MEDLINE DCOM- 20211117 LR - 20221207 IS - 1175-8716 (Electronic) IS - 0028-8446 (Linking) VI - 134 IP - 1537 DP - 2021 Jun 25 TI - Spatial, temporal and socioeconomic patterns of illicit drug use in New Zealand assessed using wastewater-based epidemiology timed to coincide with the census. PG - 11-26 AB - AIMS: A discrete experiment in wastewater-based epidemiology (WBE) timed to coincide with the census was used to investigate the spatial, temporal and socioeconomic patterns of illicit drug consumption in Auckland, Bay of Plenty and Canterbury. METHODS: For seven consecutive days over census week (6 March 2018), wastewater was sampled from seven wastewater treatment plants and analysed for methamphetamine, cocaine (as benzoylecgonine) and 3,4-methylenedioxymethamphetamine (MDMA). Detailed sewer catchment maps were developed and, together with the data, were used to analyse drug consumption. RESULTS: Methamphetamine (mean 22.9 +/- 9.9 doses/day/1000 people) was the most consumed drug, followed by MDMA (mean 1.7 +/- 1.5 doses/day/1000 people) and cocaine (mean 0.5 +/- 0.3 doses/day/1000 people). Methamphetamine consumption (and to a lesser extent MDMA) was high compared to that reported for Western nations, while cocaine consumption was extremely low. Cocaine and MDMA consumption were higher in cities compared to towns. In contrast, methamphetamine was typically higher in towns. Cocaine and MDMA were consumed more at weekends. Methamphetamine use was more consistent throughout the week. MDMA and cocaine were correlated with socioeconomic advantage, whereas methamphetamine was correlated with disadvantage. CONCLUSIONS: This paper contextualises illicit drug use in three New Zealand regions containing 18.3% of the national population and confirms the pervasiveness of methamphetamine consumption in New Zealand towns. This work demonstrates how WBE can be used to explore the socioeconomic dimensions of drug use when duly combined with other data sources like censuses. FAU - Price, Mackay AU - Price M AD - School of Environment, University of Auckland, Auckland. FAU - Wilkins, Chris AU - Wilkins C AD - Drug Research Team Leader, SHORE & Whariki Research Centre, College of Health, Massey University. FAU - Tscharke, Benjamin J AU - Tscharke BJ AD - Postdoctoral Research Fellow, Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Australia. FAU - Baker, Tom AU - Baker T AD - Senior Lecturer, School of the Environment, University of Auckland, Auckland. FAU - Mueller, Jochen F AU - Mueller JF AD - Group Leader, Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Australia. FAU - Trowsdale, Sam AU - Trowsdale S AD - Senior Lecturer, School of the Environment, University of Auckland, Auckland. LA - eng PT - Journal Article DEP - 20210625 PL - New Zealand TA - N Z Med J JT - The New Zealand medical journal JID - 0401067 RN - 0 (Narcotics) RN - 0 (Waste Water) RN - 0 (Water Pollutants, Chemical) RN - 44RAL3456C (Methamphetamine) RN - I5Y540LHVR (Cocaine) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM MH - Cocaine/analysis MH - Humans MH - Methamphetamine/analysis MH - N-Methyl-3,4-methylenedioxyamphetamine/analysis MH - Narcotics/analysis MH - New Zealand MH - Substance Abuse Detection/*methods MH - Wastewater/*chemistry MH - *Wastewater-Based Epidemiological Monitoring MH - Water Pollutants, Chemical/*chemistry COIS- Nil. EDAT- 2021/07/10 06:00 MHDA- 2021/11/18 06:00 CRDT- 2021/07/09 06:52 PHST- 2021/07/09 06:52 [entrez] PHST- 2021/07/10 06:00 [pubmed] PHST- 2021/11/18 06:00 [medline] PST - epublish SO - N Z Med J. 2021 Jun 25;134(1537):11-26.