PMID- 34239956 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220716 IS - 2345-4644 (Print) IS - 2345-461X (Electronic) IS - 2345-461X (Linking) VI - 9 IP - 3 DP - 2021 May TI - Diagnostic Accuracy of Ultrasonography Method of Graf in the detection of Developmental Dysplasia of the Hip: A Meta-Analysis and Systematic Review. PG - 297-305 LID - 10.22038/abjs.2021.55292.2755 [doi] AB - BACKGROUND: The present study aimed to perform a meta-analysis on the performance of Graf's ultrasonography method in the detection of developmental dysplasia of the hip (DDH). METHODS: A query was conducted on electronic bibliographic databases until the end of October 2020. The inclusion criteria entailed: 1. the use of Graf method in less than 12 weeks of age, 2. the use of follow-up as reference test, and 3. provision of crude data. Pooled diagnostic performance measures were calculated. Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) checklist was utilized to assess the quality of the included studies. The hierarchical summary receiver-operating characteristic (HROC) curves were also drawn. RESULTS: Six articles (including seven populations, 11,012 patients) were considered eligible. The pooled sensitivity and specificity were obtained at 93% (95% CI: 0.57-0.99) and 97% (95% CI:0.86-0.99), respectively (area under curve= 0.99). The pooled positive and negative likelihood ratio, as well as diagnostic odds ratio, was reported as 28.4, 0.07, and 396, respectively. CONCLUSION: As evidenced by the obtained results, Graf's method is a useful ultrasonography technique with acceptable accuracy for screening DDH in neonates. However, there are uncertainties about the best population and age for screening. Furthermore, more attention should be paid to the proper training of this method to reduce the number of operator errors. FAU - Chavoshi, Mohammadreza AU - Chavoshi M AD - Department of Radiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. FAU - Mirshahvalad, Seyed Ali AU - Mirshahvalad SA AD - Department of Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. FAU - Mahdizadeh, Mehrzad AU - Mahdizadeh M AD - Department of Radiology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. FAU - Zamani, Fatemeh AU - Zamani F AD - Department of Radiology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. LA - eng PT - Journal Article PT - Review PL - Iran TA - Arch Bone Jt Surg JT - The archives of bone and joint surgery JID - 101636743 PMC - PMC8221445 OTO - NOTNLM OT - DDH OT - Diagnostic performance OT - Graf OT - Meta-analysis OT - Pediatrics OT - Ultrasonography EDAT- 2021/07/10 06:00 MHDA- 2021/07/10 06:01 PMCR- 2021/05/01 CRDT- 2021/07/09 07:02 PHST- 2020/09/28 00:00 [received] PHST- 2021/02/13 00:00 [accepted] PHST- 2021/07/10 06:00 [pubmed] PHST- 2021/07/10 06:01 [medline] PHST- 2021/07/09 07:02 [entrez] PHST- 2021/05/01 00:00 [pmc-release] AID - 10.22038/abjs.2021.55292.2755 [doi] PST - ppublish SO - Arch Bone Jt Surg. 2021 May;9(3):297-305. doi: 10.22038/abjs.2021.55292.2755.