PMID- 34244847
OWN - NLM
STAT- MEDLINE
DCOM- 20211028
LR  - 20211028
IS  - 1432-1998 (Electronic)
IS  - 0301-0449 (Linking)
VI  - 51
IP  - 11
DP  - 2021 Oct
TI  - Comparison of radiation dose and image quality between contrast-enhanced single- 
      and dual-energy abdominopelvic computed tomography in children as a function of 
      patient size.
PG  - 2000-2008
LID - 10.1007/s00247-021-05127-3 [doi]
AB  - BACKGROUND: Widespread adoption of dual-energy computed tomography (DECT) 
      requires evidence it does not cause higher radiation dose than conventional 
      single-energy CT (SECT). While a few publications involving pediatric patients 
      exist, most have focused on small cohorts. Hence, there is still a need for 
      studies that ascertain what radiation doses are expected in larger populations 
      that include representative ranges of patient sizes and ages. OBJECTIVE: To 
      compare radiation dose and image quality of DECT and SECT abdominopelvic 
      examinations in children as a function of patient size. MATERIALS AND METHODS: 
      This retrospective study included 860 children (age range: 12.3+/-5.3 years) who 
      underwent contrast-enhanced abdominopelvic exams on second-generation dual-source 
      CT in a five-year period. Two groups, SECT and DECT, consisting of 430 children 
      each, were matched by 5 effective diameters. Volume CT dose index (CTDI(vol)) and 
      size-specific dose estimate (SSDE) were analyzed as a function of effective 
      diameter. Objective image quality was compared between the groups. RESULTS: DECT 
      SSDEs were lower across all effective patient diameters compared with SECT (mean: 
      8.5+/-1.8 mGv vs. 9.3+/-2.0 mGv, respectively, P</=0.001). DECT CTDI(vol) was lower 
      compared to SECT (mean: 5.6+/-2.4 mGv vs. 6.1+/-2.7 mGv, respectively, P</=0.001) 
      except in the smallest diameter group (<15 cm) where it was comparable to SECT 
      (P=0.065). Objective image quality versus effective diameter between the two CT 
      groups was comparable (P>0.05). CONCLUSION: In children, regardless of effective 
      diameter, contrast-enhanced abdominopelvic DECT can be performed with a similar 
      or lower dose and similar image quality compared with SECT examinations.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, 
      part of Springer Nature.
FAU - Siegel, Marilyn J
AU  - Siegel MJ
AD  - Mallinckrodt Institute of Radiology, Washington University School of Medicine, 
      510 S. Kingshighway Blvd., St. Louis, MO, 63110, USA. siegelm@wustl.edu.
FAU - Mhlanga, Joyce C
AU  - Mhlanga JC
AD  - Mallinckrodt Institute of Radiology, Washington University School of Medicine, 
      510 S. Kingshighway Blvd., St. Louis, MO, 63110, USA.
FAU - Salter, Amber
AU  - Salter A
AD  - Mallinckrodt Institute of Radiology, Washington University School of Medicine, 
      510 S. Kingshighway Blvd., St. Louis, MO, 63110, USA.
FAU - Ramirez-Giraldo, Juan Carlos
AU  - Ramirez-Giraldo JC
AD  - Siemens Healthineers, Malvern, PA, USA.
LA  - eng
PT  - Journal Article
DEP - 20210709
PL  - Germany
TA  - Pediatr Radiol
JT  - Pediatric radiology
JID - 0365332
SB  - IM
MH  - Adolescent
MH  - Child
MH  - *Cone-Beam Computed Tomography
MH  - Diagnostic Tests, Routine
MH  - Humans
MH  - Radiation Dosage
MH  - Retrospective Studies
MH  - *Tomography, X-Ray Computed
OTO - NOTNLM
OT  - Abdomen
OT  - Children
OT  - Computed tomography
OT  - Dual-energy computed tomography
OT  - Pelvis
OT  - Radiation dose
OT  - Single-energy computed tomography
EDAT- 2021/07/11 06:00
MHDA- 2021/10/29 06:00
CRDT- 2021/07/10 06:23
PHST- 2020/12/31 00:00 [received]
PHST- 2021/06/10 00:00 [accepted]
PHST- 2021/04/05 00:00 [revised]
PHST- 2021/07/11 06:00 [pubmed]
PHST- 2021/10/29 06:00 [medline]
PHST- 2021/07/10 06:23 [entrez]
AID - 10.1007/s00247-021-05127-3 [pii]
AID - 10.1007/s00247-021-05127-3 [doi]
PST - ppublish
SO  - Pediatr Radiol. 2021 Oct;51(11):2000-2008. doi: 10.1007/s00247-021-05127-3. Epub 
      2021 Jul 9.