PMID- 34247220
OWN - NLM
STAT- MEDLINE
DCOM- 20210720
LR  - 20220424
IS  - 1972-6007 (Electronic)
IS  - 0009-9074 (Linking)
VI  - 172
IP  - 4
DP  - 2021 Jul 5
TI  - Evaluation of Surgical and Functional Outcomes of Supracri- coid Laryngectomy and 
      Rehabilitation Protocols.
PG  - 363-368
LID - 10.7417/CT.2021.2341 [doi]
AB  - Laryngeal squamous cell carcinoma (LSCC) is the most common malignant neoplasms 
      of the head and neck. Several treatment options exist for LSCC according to 
      cancer location and stage at diagnosis; proposed treatments include surgery alone 
      or in combination with chemotherapy and radiotherapy. In selected LSCC cases in 
      the T2-T4 staging, supracricoid laryngectomy (SCL) is an organ-sparing surgical 
      approach aimed at preserving the main laryngeal functions that has been proposed 
      as an alternative to total laryngectomy. Rehabilitation for swallowing and 
      respiratory functions plays a central role after SCL; functional outcomes after 
      SCL may significantly vary among different centers but they are generally 
      satisfactory when oncological radicality has been obtained and the rehabilitation 
      protocol starts promptly. In this clinical review, we analyzed functional 
      outcomes for swallowing and voice rehabilitation in patients after SCL, as well 
      as the optimal SCL surgical technique, post-operative complications and 
      comparison with total laryngectomy or radio-chemotherapy protocols.
FAU - Ralli, M
AU  - Ralli M
AD  - Department of Sense Organs, University of Rome "Sapienza", Policlinico Umberto I, 
      Rome, Italy.
FAU - Angeletti, D
AU  - Angeletti D
AD  - Department of Sense Organs, University of Rome "Sapienza", Policlinico Umberto I, 
      Rome, Italy.
FAU - D'Aguanno, V
AU  - D'Aguanno V
AD  - Department of Sense Organs, University of Rome "Sapienza", Policlinico Umberto I, 
      Rome, Italy.
FAU - Campo, F
AU  - Campo F
AD  - Department of Sense Organs, University of Rome "Sapienza", Policlinico Umberto I, 
      Rome, Italy.
FAU - Fiore, M
AU  - Fiore M
AD  - Institute of Cell Biology and Neuro-biology, IBCN-CNR, Rome, Italy.
FAU - Greco, A
AU  - Greco A
AD  - Department of Sense Organs, University of Rome "Sapienza", Policlinico Umberto I, 
      Rome, Italy.
FAU - de Vincentiis, M
AU  - de Vincentiis M
AD  - Department of Oral and Maxillofacial Sciences, University of Rome "Sapienza", 
      Policlinico Umberto I, Rome, Italy.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Review
PL  - Italy
TA  - Clin Ter
JT  - La Clinica terapeutica
JID - 0372604
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Carcinoma, Squamous Cell/*rehabilitation/*surgery
MH  - Female
MH  - Humans
MH  - Laryngeal Neoplasms/*rehabilitation/*surgery
MH  - Laryngectomy/*methods
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/*rehabilitation
MH  - Rehabilitation/*methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - chemotherapy
OT  - laryngeal squamous cell carcinoma
OT  - radiotherapy
OT  - supracricoid laryngectomy
OT  - swallowing
OT  - total laryngectomy
EDAT- 2021/07/12 06:00
MHDA- 2021/07/21 06:00
CRDT- 2021/07/11 20:57
PHST- 2021/07/11 20:57 [entrez]
PHST- 2021/07/12 06:00 [pubmed]
PHST- 2021/07/21 06:00 [medline]
AID - 10.7417/CT.2021.2341 [doi]
PST - ppublish
SO  - Clin Ter. 2021 Jul 5;172(4):363-368. doi: 10.7417/CT.2021.2341.