PMID- 34256930 OWN - NLM STAT- MEDLINE DCOM- 20220414 LR - 20220414 IS - 1879-1883 (Electronic) IS - 0002-9610 (Linking) VI - 223 IP - 2 DP - 2022 Feb TI - Establishing the minimal clinically important difference for the Hernia-Related Quality of Life Survey (HerQLes). PG - 245-249 LID - S0002-9610(21)00349-4 [pii] LID - 10.1016/j.amjsurg.2021.06.018 [doi] AB - BACKGROUND: Hernia-Related Quality of Life Survey (HerQLes) assesses quality of life (QoL) after hernia repair, but the minimal clinically important difference (MCID) is unknown. METHODS: Using 2013-2019 data from the Abdominal Core Health Quality Collaborative, HerQLes summary scores were calculated for VHR patients at baseline and 1-year. MCID was calculated using distribution-based method. Multivariate regression identified factors associated with exceeding MCID at 1 year. RESULTS: 1817 patients met criteria. MCID was identified as a change in HerQLes of at least 15.6 points. Mean 1-year post-op score was 74.9 (SD +/- 26.2), which exceeded the MCID threshold (p < 0.001). Patients with increasing hernia width had higher odds of exceeding MCID at 1 year post-op (OR 1.04, p < 0.01), as did patients with greater ASA class (OR 8.9, p < 0.01). CONCLUSION: Using MCID can help identify patients who may significantly improve QoL after VHR, as well as power clinical trials with QoL as primary outcome. CI - Copyright (c) 2021 Elsevier Inc. All rights reserved. FAU - Renshaw, Savannah M AU - Renshaw SM AD - Center for Abdominal Core Health, Department of Surgery, Ohio State University Wexner Medical Center, 410 W 10th Ave, Columbus, OH, 43210, USA. Electronic address: savannah.renshaw@osumc.edu. FAU - Gupta, Anand AU - Gupta A AD - Center for Abdominal Core Health, Department of Surgery, Ohio State University Wexner Medical Center, 410 W 10th Ave, Columbus, OH, 43210, USA. FAU - Poulose, Benjamin K AU - Poulose BK AD - Center for Abdominal Core Health, Department of Surgery, Ohio State University Wexner Medical Center, 410 W 10th Ave, Columbus, OH, 43210, USA. LA - eng PT - Journal Article DEP - 20210702 PL - United States TA - Am J Surg JT - American journal of surgery JID - 0370473 SB - IM CIN - Am J Surg. 2022 Feb;223(2):243-244. PMID: 34330522 MH - *Hernia, Ventral/surgery MH - Herniorrhaphy MH - Humans MH - Minimal Clinically Important Difference MH - *Quality of Life MH - Treatment Outcome OTO - NOTNLM OT - Hernia OT - MCID OT - Quality of life EDAT- 2021/07/15 06:00 MHDA- 2022/04/15 06:00 CRDT- 2021/07/14 05:45 PHST- 2021/04/23 00:00 [received] PHST- 2021/06/15 00:00 [revised] PHST- 2021/06/28 00:00 [accepted] PHST- 2021/07/15 06:00 [pubmed] PHST- 2022/04/15 06:00 [medline] PHST- 2021/07/14 05:45 [entrez] AID - S0002-9610(21)00349-4 [pii] AID - 10.1016/j.amjsurg.2021.06.018 [doi] PST - ppublish SO - Am J Surg. 2022 Feb;223(2):245-249. doi: 10.1016/j.amjsurg.2021.06.018. Epub 2021 Jul 2.