PMID- 34272347
OWN - NLM
STAT- MEDLINE
DCOM- 20211209
LR  - 20211214
IS  - 1899-1505 (Electronic)
IS  - 0867-5910 (Linking)
VI  - 72
IP  - 1
DP  - 2021 Feb
TI  - Sleep quality mediates the relationship between risk of obstructive sleep apnea 
      and acute stress in young adults.
LID - 10.26402/jpp.2021.1.11 [doi]
AB  - Intermittent hypoxia and transient arousals in obstructive sleep apnea (OSA) can 
      lead to poor sleep quality and acute stress. Rising levels of obesity and 
      increased incidence of OSA in young adults predisposes them to acute stress. We 
      propose a mediation model to assess if risk of OSA is associated with acute 
      stress and if the relationship between risk for OSA and acute stress is mediated 
      by sleep quality. 493 healthy individuals (F = 237, M = 256) from 18 - 25 years 
      of age (mean age 20.3 +/- 1.53 years) were screened for OSA, sleep quality and 
      acute stress using STOP-BANG questionnaire, Pittsburg Sleep Quality Index and 
      American Psychiatry Association's National Stressful Events Survey Acute Stress 
      Disorder Short Scale (NSESS-S), respectively. 73 participants (17.3%) were found 
      at an intermediate and high risk of OSA by STOP BANG questionnaire. 79 (16%) 
      participants reported level of stress as 'None'. Mild, moderate and severe stress 
      was present in 248 (50.3%), 109 (22.1%), 51 (10.3%) and 16 (3.2%) participants, 
      respectively. The odds of having severe and extreme stress among those at risk of 
      sleep apnea is 2.18 times higher than that among those not at risk of sleep apnea 
      (OR: 2.18, 95%, confidence interval: 1.37-3.51). Sobel test established that the 
      relationship between OSA and acute stress is mediated by sleep quality. Sleep 
      quality mediates the relationship between risk for sleep apnea and acute stress. 
      This highlights the importance of screening for OSA in young adults, particularly 
      young men with high BMI, presenting with high stress levels.
FAU - Aggarwal, K
AU  - Aggarwal K
AD  - India Institute of Medical Sciences, New Delhi, India.
FAU - Akhtar, N
AU  - Akhtar N
AD  - Department of Physiology, All India Institute of Medical Sciences, New Delhi, 
      India. drnasreenakhtar@gmail.com.
FAU - Mallick, H
AU  - Mallick H
AD  - Department of Physiology, Faculty of Medicine and Health Sciences, SGT 
      University, Gurgaon, Haryana, India.
LA  - eng
PT  - Journal Article
DEP - 20210713
PL  - Poland
TA  - J Physiol Pharmacol
JT  - Journal of physiology and pharmacology : an official journal of the Polish 
      Physiological Society
JID - 9114501
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Female
MH  - Humans
MH  - Male
MH  - Mass Screening/methods
MH  - Risk
MH  - Severity of Illness Index
MH  - Sleep Apnea, Obstructive/*complications/psychology
MH  - *Sleep Quality
MH  - Stress, Psychological/diagnosis/*epidemiology/etiology
MH  - Surveys and Questionnaires
MH  - Young Adult
EDAT- 2021/07/18 06:00
MHDA- 2021/12/15 06:00
CRDT- 2021/07/17 05:45
PHST- 2021/02/10 00:00 [received]
PHST- 2021/02/26 00:00 [accepted]
PHST- 2021/07/17 05:45 [entrez]
PHST- 2021/07/18 06:00 [pubmed]
PHST- 2021/12/15 06:00 [medline]
AID - 10.26402/jpp.2021.1.11 [doi]
PST - ppublish
SO  - J Physiol Pharmacol. 2021 Feb;72(1). doi: 10.26402/jpp.2021.1.11. Epub 2021 Jul 
      13.