PMID- 34272469
OWN - NLM
STAT- MEDLINE
DCOM- 20211021
LR  - 20230205
IS  - 1476-5543 (Electronic)
IS  - 0743-8346 (Linking)
VI  - 41
IP  - 10
DP  - 2021 Oct
TI  - Adverse events associated with umbilical catheters: a systematic review and 
      meta-analysis.
PG  - 2505-2512
LID - 10.1038/s41372-021-01147-x [doi]
AB  - OBJECTIVE: To determine the incidence of adverse events (AEs) associated with 
      umbilical catheters in the neonatal population. STUDY DESIGN: Systematic review 
      and meta-analysis of observational studies and randomized controlled trials 
      published between 2010 and 2020. RESULTS: In total 14,226 umbilical venous 
      catheters (UVCs) and 4228 umbilical arterial catheters (UACs) were included. 
      Overall, 13.4% of UVCs were associated with an AE (95% CI: 10.1-17.0) or 2.4 per 
      1000 catheter days (95% CI: 1.8-3.0). UACs had an AE rate of 9% (95% CI: 
      5.9-12.8) or 0.87 per 1000 catheter days (95% CI: 0.4-1.3). UVC malposition was 
      the most common (41.7% [95% CI: 27.6-56.5]). Local injury from UAC taping was the 
      most common AE in one study. CONCLUSIONS: Umbilical catheters have a high 
      incidence of AEs. Research into accurate methods of tip verification, tip 
      surveillance, and securement is required.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer Nature America, Inc.
FAU - Gibson, Kim
AU  - Gibson K
AUID- ORCID: 0000-0002-4174-5653
AD  - Clinical and Health Sciences, Rosemary Bryant AO Research Centre, University of 
      South Australia, Adelaide, SA, Australia. Kim.gibson@unisa.edu.au.
FAU - Sharp, Rebecca
AU  - Sharp R
AD  - Clinical and Health Sciences, Rosemary Bryant AO Research Centre, University of 
      South Australia, Adelaide, SA, Australia.
FAU - Ullman, Amanda
AU  - Ullman A
AD  - Children's Health Queensland and Health Service, Centre of Children's Health 
      Research, South Brisbane, QLD, Australia.
AD  - School of Nursing, Midwifery and Social Work, The University of Queensland, 
      Brisbane, QLD, Australia.
FAU - Morris, Scott
AU  - Morris S
AD  - Neonatal Unit, Flinders Medical Centre, Bedford Park, SA, Australia.
AD  - College of Medicine and Public Health, Flinders University, Adelaide, Australia.
FAU - Kleidon, Tricia
AU  - Kleidon T
AD  - Queensland Children's Hospital, South Brisbane, QLD, Australia.
FAU - Esterman, Adrian
AU  - Esterman A
AD  - Clinical and Health Sciences, Rosemary Bryant AO Research Centre, University of 
      South Australia, Adelaide, SA, Australia.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
DEP - 20210716
PL  - United States
TA  - J Perinatol
JT  - Journal of perinatology : official journal of the California Perinatal 
      Association
JID - 8501884
SB  - IM
MH  - *Catheterization, Peripheral/adverse effects
MH  - Catheters/adverse effects
MH  - Catheters, Indwelling/adverse effects
MH  - Humans
MH  - Infant, Newborn
MH  - Umbilical Veins
MH  - Umbilicus
MH  - *Vascular Access Devices
EDAT- 2021/07/18 06:00
MHDA- 2023/02/02 06:00
CRDT- 2021/07/17 06:11
PHST- 2021/03/25 00:00 [received]
PHST- 2021/06/30 00:00 [accepted]
PHST- 2021/06/11 00:00 [revised]
PHST- 2021/07/18 06:00 [pubmed]
PHST- 2023/02/02 06:00 [medline]
PHST- 2021/07/17 06:11 [entrez]
AID - 10.1038/s41372-021-01147-x [pii]
AID - 10.1038/s41372-021-01147-x [doi]
PST - ppublish
SO  - J Perinatol. 2021 Oct;41(10):2505-2512. doi: 10.1038/s41372-021-01147-x. Epub 
      2021 Jul 16.