PMID- 34273524
OWN - NLM
STAT- MEDLINE
DCOM- 20220228
LR  - 20220228
IS  - 1873-6513 (Electronic)
IS  - 0885-3924 (Linking)
VI  - 63
IP  - 1
DP  - 2022 Jan
TI  - Dyspnoea-12 and Multidimensional Dyspnea Profile: Systematic Review of Use and 
      Properties.
PG  - e75-e87
LID - S0885-3924(21)00422-X [pii]
LID - 10.1016/j.jpainsymman.2021.06.023 [doi]
AB  - CONTEXT: The Dyspnoea-12 (D-12) and Multidimensional Dyspnea Profile (MDP) were 
      specifically developed for assessment of multiple sensations of breathlessness. 
      OBJECTIVES: This systematic review aimed to identify the use and measurement 
      properties of the D-12 and MDP across populations, settings and languages. 
      METHODS: Electronic databases were searched for primary studies (2008-2020) 
      reporting use of the D-12 or MDP in adults. Two independent reviewers completed 
      screening and data extraction. Study and participant characteristics, instrument 
      use, reported scores and minimal clinical important differences (MCID) were 
      evaluated. Data on internal consistency (Cronbach's alpha) and test-retest 
      reliability (intraclass correlation coefficient, ICC) were pooled using random 
      effects models between settings and languages. RESULTS: A total 75 publications 
      reported use of D-12 (n = 35), MDP (n = 37) or both (n = 3), reflecting 16 
      chronic conditions. Synthesis confirmed two factor structure, internal 
      consistency (Cronbach's alpha mean, 95% CI: D-12 Total = 0.93, 0.91-0.94; MDP 
      Immediate Perception [IP] = 0.88, 0.85-0.90; MDP Emotional Response [ER] = 0.86, 
      0.82-0.89) and 14 day test-rest reliability (ICC: D-12 Total = 0.91, 0.88-0.94; 
      MDP IP = 0.85, 0.70-0.93; MDP ER = 0.84, 0.73-0.90) across settings and 
      languages. MCID estimates for clinical interventions ranged between -3 and -6 
      points (D-12 Total) with small variability in scores over 2 weeks (D-12 Total 2.8 
      (95% CI: 2.0 to 3.7), MDP-A1 0.8 (0.6 to 1.1) and six months (D-12 Total 2.9 (2.0 
      to 3.7), MDP-A1 0.8 (0.6 to 1.1)). CONCLUSION: D-12 and MDP are widely used, 
      reliable, valid and responsive across various chronic conditions, settings and 
      languages, and could be considered standard instruments for measuring dimensions 
      of breathlessness in international trials.
CI  - Copyright (c) 2021 The Authors. Published by Elsevier Inc. All rights reserved.
FAU - Williams, Marie T
AU  - Williams MT
AD  - Allied Health and Human Performance, University of South Australia, Adelaide, 
      South Australia, Australia. Electronic address: Marie.williams@unisa.edu.au.
FAU - Lewthwaite, Hayley
AU  - Lewthwaite H
AD  - Allied Health and Human Performance, University of South Australia, Adelaide, 
      South Australia, Australia; Department of Kinesiology and Physical Education, 
      McGill University, Montreal, Quebec, Canada; College of Engineering, Science and 
      Environment, School of Environmental & Life Sciences, University of Newcastle, 
      Ourimbah, New South Wales, Australia.
FAU - Paquet, Catherine
AU  - Paquet C
AD  - Allied Health and Human Performance, University of South Australia, Adelaide, 
      South Australia, Australia; Faculte des Sciences de l'Administration, Universite 
      Laval, Quebec (Quebec) , Canada.
FAU - Johnston, Kylie
AU  - Johnston K
AD  - Allied Health and Human Performance, University of South Australia, Adelaide, 
      South Australia, Australia.
FAU - Olsson, Max
AU  - Olsson M
AD  - Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, 
      Respiratory Medicine and Allergology, Lund, Sweden.
FAU - Belo, Leticia Fernandes
AU  - Belo LF
AD  - Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of 
      Physiotherapy, State University of Londrina (UEL), Londrina, Brazil.
FAU - Pitta, Fabio
AU  - Pitta F
AD  - Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of 
      Physiotherapy, State University of Londrina (UEL), Londrina, Brazil.
FAU - Morelot-Panzini, Capucine
AU  - Morelot-Panzini C
AD  - Sorbonne Universite, INSERM, UMRS1158 Neurophysiologie Respiratoire Experimentale 
      et Clinique, Paris, France; Groupe Hospitalo-Universitaire APHP-Sorbonne 
      Universite, site Pitie-Salpetriere, Service de Pneumologie, Departement R3S, 
      Paris, France.
FAU - Ekstrom, Magnus
AU  - Ekstrom M
AD  - Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, 
      Respiratory Medicine and Allergology, Lund, Sweden.
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20210715
PL  - United States
TA  - J Pain Symptom Manage
JT  - Journal of pain and symptom management
JID - 8605836
SB  - IM
MH  - Adult
MH  - *Dyspnea/diagnosis/psychology
MH  - *Emotions
MH  - Humans
MH  - Language
MH  - Psychometrics/methods
MH  - Reproducibility of Results
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - Systematic review
OT  - assessment
OT  - breathlessness
OT  - dyspnea
OT  - psychometric
EDAT- 2021/07/18 06:00
MHDA- 2022/03/01 06:00
CRDT- 2021/07/17 20:13
PHST- 2021/04/28 00:00 [received]
PHST- 2021/06/22 00:00 [revised]
PHST- 2021/06/26 00:00 [accepted]
PHST- 2021/07/18 06:00 [pubmed]
PHST- 2022/03/01 06:00 [medline]
PHST- 2021/07/17 20:13 [entrez]
AID - S0885-3924(21)00422-X [pii]
AID - 10.1016/j.jpainsymman.2021.06.023 [doi]
PST - ppublish
SO  - J Pain Symptom Manage. 2022 Jan;63(1):e75-e87. doi: 
      10.1016/j.jpainsymman.2021.06.023. Epub 2021 Jul 15.