PMID- 34278894
OWN - NLM
STAT- MEDLINE
DCOM- 20220426
LR  - 20220602
IS  - 1532-7914 (Electronic)
IS  - 0163-5581 (Linking)
VI  - 74
IP  - 4
DP  - 2022
TI  - Dietary Antioxidant Capacity and Serum Inflammatory Biomarkers Levels in Cancer 
      Survivors.
PG  - 1243-1251
LID - 10.1080/01635581.2021.1952443 [doi]
AB  - This study aimed to compare the dietary intake of carotenoids, tocopherols, 
      ascorbic acid, flavonoids, and dietary total antioxidant capacity (dTAC) and to 
      evaluate relationship of dTAC with serum inflammatory biomarkers in patients with 
      gastrointestinal system (GIS) and non-GIS cancer. In total, 104 adult cancer 
      survivors (52 GIS and 52 non-GIS cancer cases) were included. 24-hour dietary 
      recalls were obtained and dTAC was calculated on the basis of oxygen radical 
      absorption capacity (ORAC), Trolox equivalent antioxidant capacity (TEAC), total 
      radical-trapping antioxidant parameter (TRAP), ferric reducing antioxidant 
      potential (FRAP), and vitamin C equivalents (VCE). Serum C-reactive protein (CRP) 
      level, neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) 
      were used as inflammatory biomarkers. Routinely analyzed serum CRP, neutrophil, 
      lymphocyte, and platelet levels every day in hospital biochemistry laboratory 
      were obtained from patients' file. There was no significant difference between 
      patients with GIS and non-GIS cancer in terms of dietary intake of carotenoids, 
      tocopherols, and flavonoids. While there was no significant difference between 
      groups in terms of the mean dietary ORAC, TEAC, and FRAP, the mean TRAP of 
      patients with GIS cancer was significantly higher than patients with non-GIS 
      cancer. Serum inflammatory markers (CRP and NLR) were found to have an inverse 
      relationship with dTAC.
FAU - Alkan, Senay Burcin
AU  - Alkan SB
AD  - Department of Nutrition and Dietetics, Faculty of Health Sciences, Necmettin 
      Erbakan University, Konya, Turkey.
FAU - Artac, Mehmet
AU  - Artac M
AD  - Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
FAU - Rakicioglu, Neslisah
AU  - Rakicioglu N
AD  - Department of Nutrition and Dietetics, Faculty of Health Sciences, Hacettepe 
      University, Ankara, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20210719
PL  - United States
TA  - Nutr Cancer
JT  - Nutrition and cancer
JID - 7905040
RN  - 0 (Antioxidants)
RN  - 0 (Biomarkers)
RN  - 0 (Flavonoids)
RN  - 0 (Reactive Oxygen Species)
RN  - 36-88-4 (Carotenoids)
RN  - 9007-41-4 (C-Reactive Protein)
RN  - PQ6CK8PD0R (Ascorbic Acid)
RN  - R0ZB2556P8 (Tocopherols)
SB  - IM
MH  - Adult
MH  - Antioxidants/metabolism
MH  - Ascorbic Acid
MH  - Biomarkers
MH  - C-Reactive Protein
MH  - *Cancer Survivors
MH  - Carotenoids
MH  - Flavonoids
MH  - Humans
MH  - *Neoplasms
MH  - Reactive Oxygen Species/metabolism
MH  - Tocopherols
EDAT- 2021/07/20 06:00
MHDA- 2022/04/27 06:00
CRDT- 2021/07/19 08:42
PHST- 2021/07/20 06:00 [pubmed]
PHST- 2022/04/27 06:00 [medline]
PHST- 2021/07/19 08:42 [entrez]
AID - 10.1080/01635581.2021.1952443 [doi]
PST - ppublish
SO  - Nutr Cancer. 2022;74(4):1243-1251. doi: 10.1080/01635581.2021.1952443. Epub 2021 
      Jul 19.