PMID- 34283525 OWN - NLM STAT- MEDLINE DCOM- 20210722 LR - 20210722 IS - 1997-7298 (Print) IS - 1997-7298 (Linking) VI - 121 IP - 6 DP - 2021 TI - [Cognitive impairment and social functioning in organic personality disorder due to epilepsy]. PG - 21-26 LID - 10.17116/jnevro202112106121 [doi] AB - OBJECTIVE: To develop criteria for the diagnosis of cognitive impairment (CI) and to determine the degree of social functioning in organic personality disorder due to epilepsy. MATERIAL AND METHODS: One hundred and twenty-six patients with epilepsy, aged 18 to 65 years, with disease duration of 11 to 20 years, were examined. The main research method is clinical-psychopathological. The Mini-mental state examination (MMSE) was administered to assess the severity of CI. The Global Assessment of Functioning (GAF) scale was used to assess social functioning. RESULTS AND CONCLUSION: The structure of organic personality disorder due to epilepsy is determined by a combination of CI and personality changes with a predominance of explosive (short temper, irritability, brutality, explosiveness) or defensive (passivity, suggestibility, vulnerability, suspiciousness, sensitivity, subordination) traits. CI includes impaired thinking, attention, and memory and is manifested by inertia, stiffness, toughness, rigidity, slowing down the pace of thought processes, as well as difficulty in concentrating, impaired direct and indirect memory. Three groups of patients with mild, moderate and severe CI are isolated. In the group with mild CI, thorough thinking with a slow pace and a decrease in the ability to learn new things, which was com. When assessing impairment of social functioning fa moderate and severe of maladaptation with impairments in all areas of activity is revealed in people with explosive personality characteristics and a mild degree - in people with defensive features. It has been shown that the analysis of cognitive impairment is critical in the diagnosis of organic personality disorder due to epilepsy. FAU - Usykina, M V AU - Usykina MV AUID- ORCID: 0000-0002-2670-4378 AD - Serbsky National Medical Research Center for Psychiatry and Narcology, Moscow, Russia. FAU - Kornilova, S V AU - Kornilova SV AUID- ORCID: 0000-0003-2581-9744 AD - Serbsky National Medical Research Center for Psychiatry and Narcology, Moscow, Russia. FAU - Lavrushchik, M V AU - Lavrushchik MV AUID- ORCID: 0000-0002-8961-795X AD - Serbsky National Medical Research Center for Psychiatry and Narcology, Moscow, Russia. LA - rus PT - Journal Article TT - Kognitivnye narusheniya i sotsial'noe funktsionirovanie pri organicheskom rasstroistve lichnosti vsledstvie epilepsii. PL - Russia (Federation) TA - Zh Nevrol Psikhiatr Im S S Korsakova JT - Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova JID - 9712194 SB - IM MH - *Cognitive Dysfunction/diagnosis/etiology MH - *Epilepsy/diagnosis/etiology MH - Humans MH - Personality Disorders/diagnosis/etiology MH - *Psychotic Disorders MH - Social Interaction OTO - NOTNLM OT - cognitive impairment OT - epilepsy OT - organic personality disorder OT - social functioning EDAT- 2021/07/21 06:00 MHDA- 2021/07/23 06:00 CRDT- 2021/07/20 16:28 PHST- 2021/07/20 16:28 [entrez] PHST- 2021/07/21 06:00 [pubmed] PHST- 2021/07/23 06:00 [medline] AID - 10.17116/jnevro202112106121 [doi] PST - ppublish SO - Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121(6):21-26. doi: 10.17116/jnevro202112106121.