PMID- 34286121
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220425
IS  - 2405-8440 (Print)
IS  - 2405-8440 (Electronic)
IS  - 2405-8440 (Linking)
VI  - 7
IP  - 7
DP  - 2021 Jul
TI  - Gestational diabetes in rural central India: low prevalence but absence of 
      typical risk factors.
PG  - e07431
LID - 10.1016/j.heliyon.2021.e07431 [doi]
LID - e07431
AB  - INTRODUCTION: The reported prevalence of gestational diabetes mellitus (GDM) 
      varies widely across India. Given the short-term, long-term, and 
      multigenerational health impacts of GDM, understanding its frequency and risk 
      factors is important for population screening strategies. We estimated the 
      prevalence of GDM and determined associated risk factors in rural, central India, 
      where data is sparse. METHODS: We conducted a cross-sectional study of a 
      convenience sample of 575 pregnant women attending antenatal care (ANC) clinics 
      at Jan Swasthya Sahyog's (JSS) outreach clinics in rural Chhattisgarh, India. 
      Study participants underwent a non-fasting 75g oral glucose tolerance test (OGTT) 
      between 24-28 weeks gestation. Using Diabetes in Pregnancy Study Group of India 
      (DIPSI) criteria, a 2-hour post-OGTT glucose >/=140 mg/dL was used to diagnose GDM. 
      RESULTS: We found 11 patients (1.9%) who met diagnostic criteria for GDM. Median 
      age, systolic blood pressure, and diastolic blood pressure were higher in those 
      with GDM (26 vs 23 years, p = 0.02; 117 vs 106 mmHg, p = 0.04, 77 vs 68 mmHg, p < 
      0.01, respectively). Pre-hypertension was associated with increased odds of GDM 
      on multivariate analysis (OR 4.0, 95% CI: 1.1, 14.8). BMI was not associated with 
      GDM. With appropriate management there were no differences in fetal complications 
      between GDM and normal glucose tolerance (NGT) groups. CONCLUSIONS: In rural, 
      central India the prevalence of GDM was 1.9% in the absence of traditional risk 
      factors such as increased BMI. Further research is needed to define the 
      applicability of optimal screening strategies in such settings.
CI  - (c) 2021 The Authors.
FAU - Chebrolu, Puja
AU  - Chebrolu P
AD  - Jan Swasthya Sahyog, India.
FAU - Kurbude, Ravi
AU  - Kurbude R
AD  - Jan Swasthya Sahyog, India.
FAU - Thakur, Manju
AU  - Thakur M
AD  - Jan Swasthya Sahyog, India.
FAU - Shah, Naman
AU  - Shah N
AD  - Jan Swasthya Sahyog, India.
FAU - Jain, Rachna
AU  - Jain R
AD  - Jan Swasthya Sahyog, India.
LA  - eng
PT  - Journal Article
DEP - 20210628
PL  - England
TA  - Heliyon
JT  - Heliyon
JID - 101672560
PMC - PMC8273204
OTO - NOTNLM
OT  - Gestational diabetes
OT  - India
OT  - Screening
COIS- The authors declare no conflict of interest.
EDAT- 2021/07/22 06:00
MHDA- 2021/07/22 06:01
PMCR- 2021/06/28
CRDT- 2021/07/21 06:38
PHST- 2021/02/01 00:00 [received]
PHST- 2021/06/08 00:00 [revised]
PHST- 2021/06/24 00:00 [accepted]
PHST- 2021/07/21 06:38 [entrez]
PHST- 2021/07/22 06:00 [pubmed]
PHST- 2021/07/22 06:01 [medline]
PHST- 2021/06/28 00:00 [pmc-release]
AID - S2405-8440(21)01534-6 [pii]
AID - e07431 [pii]
AID - 10.1016/j.heliyon.2021.e07431 [doi]
PST - epublish
SO  - Heliyon. 2021 Jun 28;7(7):e07431. doi: 10.1016/j.heliyon.2021.e07431. eCollection 
      2021 Jul.