PMID- 34289902
OWN - NLM
STAT- MEDLINE
DCOM- 20210723
LR  - 20240402
IS  - 1756-0500 (Electronic)
IS  - 1756-0500 (Linking)
VI  - 14
IP  - 1
DP  - 2021 Jul 21
TI  - High carbohydrate intakes may predict more inflammatory status than high fat 
      intakes in pre-menopause women with overweight or obesity: a cross-sectional 
      study.
PG  - 279
LID - 10.1186/s13104-021-05699-1 [doi]
LID - 279
AB  - OBJECTIVE: The associations between dietary carbohydrate, fat intake, and 
      inflammation are controversial. Most existing data are from industrialized 
      societies which low-carbohydrate and high-fat diet is common and so their 
      attribution to other populations remains unclear. We evaluated the association of 
      fat and carbohydrate intakes with inflammatory markers in pre-menopause women 
      with overweight or obesity in Iran. RESULTS: Three hundred and sixty women with 
      body mass index (BMI) >/= 25 were included to this study. The levels of monocyte 
      chemoattractant protein-1 (MCP-1) indicated a trend towards significance across 
      tertiles of total dietary carbohydrate. We found that the levels of galectin-3 
      were negatively associated with dietary carbohydrate in adjusted model. In 
      addition, the levels of MCP-1 and transforming growth factor beta (TGF-beta) were 
      positively correlated to dietary carbohydrate. No significant relationship was 
      demonstrated between inflammatory parameters and total fat intake). However, 
      there was a borderline significant negative association between total fat intake 
      and TGF-beta level in adjusted model. Therefore, a total dietary carbohydrate were 
      related to elevated inflammation risk, while a total fat intake were not 
      associated to higher inflammation. This study suggests reconsideration of 
      applying global dietary guidelines in societies with high carbohydrate diet.
CI  - (c) 2021. The Author(s).
FAU - Karimi, Elmira
AU  - Karimi E
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences (TUMS), P.O. Box: 14155-6117, Tehran, Iran.
FAU - Yarizadeh, Habib
AU  - Yarizadeh H
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences (TUMS), P.O. Box: 14155-6117, Tehran, Iran.
FAU - Setayesh, Leila
AU  - Setayesh L
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences (TUMS), P.O. Box: 14155-6117, Tehran, Iran.
FAU - Sajjadi, Seyyedeh Forough
AU  - Sajjadi SF
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences (TUMS), P.O. Box: 14155-6117, Tehran, Iran.
FAU - Ghodoosi, Nasim
AU  - Ghodoosi N
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences (TUMS), P.O. Box: 14155-6117, Tehran, Iran.
FAU - Khorraminezhad, Leil
AU  - Khorraminezhad L
AD  - Endocrinology and Nephrology Unit, CHU de Quebec-Laval University, Research 
      Center, Quebec, QC, Canada.
FAU - Mirzaei, Khadijeh
AU  - Mirzaei K
AUID- ORCID: 0000-0002-7554-8551
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences (TUMS), P.O. Box: 14155-6117, Tehran, Iran. 
      mirzaei_kh@tums.ac.ir.
LA  - eng
GR  - 95-03-161-33142/Tehran University of Medical Sciences and Health Services/
GR  - 97-03-161-41017/Tehran University of Medical Sciences and Health Services/
GR  - 97-03-161-41144/Tehran University of Medical Sciences and Health Services/
PT  - Journal Article
DEP - 20210721
PL  - England
TA  - BMC Res Notes
JT  - BMC research notes
JID - 101462768
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
SB  - IM
MH  - Body Mass Index
MH  - Cross-Sectional Studies
MH  - Diet
MH  - Dietary Carbohydrates
MH  - Dietary Fats
MH  - Energy Intake
MH  - Female
MH  - Humans
MH  - Iran
MH  - *Obesity
MH  - Overweight
MH  - *Premenopause
PMC - PMC8296741
OTO - NOTNLM
OT  - Dietary carbohydrate
OT  - Dietary fat
OT  - Inflammation
OT  - Obesity
OT  - Pre-menopause
COIS- The authors in the study declared no conflict of interests.
EDAT- 2021/07/23 06:00
MHDA- 2021/07/24 06:00
PMCR- 2021/07/21
CRDT- 2021/07/22 05:38
PHST- 2021/03/08 00:00 [received]
PHST- 2021/07/14 00:00 [accepted]
PHST- 2021/07/22 05:38 [entrez]
PHST- 2021/07/23 06:00 [pubmed]
PHST- 2021/07/24 06:00 [medline]
PHST- 2021/07/21 00:00 [pmc-release]
AID - 10.1186/s13104-021-05699-1 [pii]
AID - 5699 [pii]
AID - 10.1186/s13104-021-05699-1 [doi]
PST - epublish
SO  - BMC Res Notes. 2021 Jul 21;14(1):279. doi: 10.1186/s13104-021-05699-1.