PMID- 34291991 OWN - NLM STAT- MEDLINE DCOM- 20220323 LR - 20220413 IS - 1936-2293 (Electronic) IS - 1064-1297 (Linking) VI - 30 IP - 2 DP - 2022 Apr TI - Verbal behavior related to drug reinforcement in polysubstance cannabis users: Comparison across drugs. PG - 172-179 LID - 10.1037/pha0000404 [doi] AB - Verbal reports of drug effects are often used in behavioral pharmacology. Two reports related to reinforcement are drug use (Harford, 1978; Liu et al., 2018) frequency and drug preference. Anecdotally, some individuals may specify a favorite/preferred drug (e.g., psilocybin) despite using another drug more frequently (e.g., tobacco). Research comparing these two measures has led to contradictory findings and included ratings from participants who may not have experience with the rated drugs. No comparisons have been made between use frequency and preference across multiple drugs in polysubstance users. To compare use frequency and preference for drug classes, and examine relations across drug classes, individuals reporting polysubstance use (N = 428) provided frequency and preference ratings for nine drug classes. Mean ratings showed smoked tobacco, alcohol, and cannabis were the most frequently used and most preferred drugs. Mean ratings showed 3,4-Methylenedioxymethamphetamine (MDMA) and classic hallucinogens were the least frequently used and least preferred drugs. However, more divergence between use frequency and preference was observed when these metrics were examined among individuals. Correlation coefficients between use frequency and preference were lower than previously published literature. The majority of polydrug comparisons were nonsignificant, and correlations between different drug classes differed depending on whether use frequency or preference was examined. Verbal reports about use frequency are likely not strongly predictive of verbal reports about the same drug preference. Clinicians and researchers should recognize that different verbal reports related to drug reinforcement might be proxies for distinct aspects of reinforcement and should consider these implications for assessment and research findings. (PsycInfo Database Record (c) 2022 APA, all rights reserved). FAU - Cox, David J AU - Cox DJ AUID- ORCID: 0000-0003-4376-2104 AD - Behavioral Pharmacology Research Unit. FAU - Johnson, Matthew W AU - Johnson MW AD - Behavioral Pharmacology Research Unit. LA - eng GR - R01 DA032363/DA/NIDA NIH HHS/United States PT - Journal Article DEP - 20210722 PL - United States TA - Exp Clin Psychopharmacol JT - Experimental and clinical psychopharmacology JID - 9419066 RN - 0 (Hallucinogens) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM MH - *Cannabis MH - *Hallucinogens/pharmacology MH - Humans MH - *N-Methyl-3,4-methylenedioxyamphetamine MH - *Substance-Related Disorders/epidemiology MH - Verbal Behavior EDAT- 2021/07/23 06:00 MHDA- 2022/03/24 06:00 CRDT- 2021/07/22 12:16 PHST- 2021/07/23 06:00 [pubmed] PHST- 2022/03/24 06:00 [medline] PHST- 2021/07/22 12:16 [entrez] AID - 2021-64596-001 [pii] AID - 10.1037/pha0000404 [doi] PST - ppublish SO - Exp Clin Psychopharmacol. 2022 Apr;30(2):172-179. doi: 10.1037/pha0000404. Epub 2021 Jul 22.