PMID- 34296159
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210724
IS  - 2632-7376 (Electronic)
IS  - 2632-7376 (Linking)
VI  - 2
IP  - 2
DP  - 2021
TI  - Neural Representations of Death in the Cortical Midline Structures Promote 
      Temporal Discounting.
PG  - tgab013
LID - 10.1093/texcom/tgab013 [doi]
LID - tgab013
AB  - Death is an important reminder that our lives are finite. Although some studies 
      have shown that thinking about one's own death increases temporal discounting 
      (i.e., the devaluing of future rewards), the underlying neural mechanisms are 
      still unknown. In a functional magnetic resonance imaging experiment, we compared 
      the neural and behavioral processes of temporal discounting across four 
      conditions involving distinct types of future thinking (death related, negative, 
      neutral, and positive). Replicating prior research, the behavioral evidence 
      showed that temporal discounting increased when thinking about one's own future 
      death. Multivoxel pattern analysis showed that death-related future thinking was 
      decoded in default mode regions, including the inferior parietal lobule, 
      precuneus, and medial prefrontal cortex (MPFC). When future thinking was death 
      related (vs. negative), increased temporal discounting was associated with a 
      higher decoding accuracy in the precuneus and MPFC. The present findings suggest 
      that death-related neural representations are distributed across default mode 
      regions, and neural populations in the cortical midline structures play a crucial 
      role in the integration of one's own death into economic decision-making.
CI  - (c) The Author(s) 2021. Published by Oxford University Press.
FAU - Yanagisawa, Kuniaki
AU  - Yanagisawa K
AUID- ORCID: 0000-0003-0644-5847
AD  - Department of Psychology, Graduate School of Humanities, Kobe University, Kobe 
      657-8501 Japan.
FAU - Kashima, Emiko S
AU  - Kashima ES
AD  - School of Psychology and Public Health, La Trobe University, Bundoora, Vic 3086, 
      Australia.
FAU - Shigemune, Yayoi
AU  - Shigemune Y
AD  - Research and Development Initiative, Chuo University, Tokyo 192-0393, Japan.
FAU - Nakai, Ryusuke
AU  - Nakai R
AD  - Kokoro Research Center, Kyoto University, Kyoto 606-8501, Japan.
FAU - Abe, Nobuhito
AU  - Abe N
AD  - Kokoro Research Center, Kyoto University, Kyoto 606-8501, Japan.
LA  - eng
PT  - Journal Article
DEP - 20210222
PL  - United States
TA  - Cereb Cortex Commun
JT  - Cerebral cortex communications
JID - 101767128
PMC - PMC8152905
OTO - NOTNLM
OT  - MVPA
OT  - death-related information
OT  - default mode
OT  - delay discounting
OT  - fMRI
EDAT- 2021/07/24 06:00
MHDA- 2021/07/24 06:01
PMCR- 2021/02/22
CRDT- 2021/07/23 06:55
PHST- 2020/06/09 00:00 [received]
PHST- 2021/02/08 00:00 [revised]
PHST- 2021/02/10 00:00 [accepted]
PHST- 2021/07/23 06:55 [entrez]
PHST- 2021/07/24 06:00 [pubmed]
PHST- 2021/07/24 06:01 [medline]
PHST- 2021/02/22 00:00 [pmc-release]
AID - tgab013 [pii]
AID - 10.1093/texcom/tgab013 [doi]
PST - epublish
SO  - Cereb Cortex Commun. 2021 Feb 22;2(2):tgab013. doi: 10.1093/texcom/tgab013. 
      eCollection 2021.