PMID- 34300332
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210729
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 10
IP  - 14
DP  - 2021 Jul 18
TI  - The 1-Year Safety and Efficacy Outcomes of Magmaris, Novel Magnesium 
      Bioresorbable Vascular Scaffolds in Diabetes Mellitus Patients with Acute 
      Coronary Syndrome.
LID - 10.3390/jcm10143166 [doi]
LID - 3166
AB  - BACKGROUND: Diabetes mellitus (DM) is one of the major risk factors contributing 
      to Acute Coronary Syndromes (ACS) and is associated with an increased risk of 
      adverse clinical outcomes following percutaneous coronary intervention (PCI), 
      even when the second generation of drug-eluting stents (DES) is used. In order to 
      overcome the disadvantages of permanent caging of a vessel with metallic DES, 
      bioresorbable scaffold (BRS) technology has been recently developed. However, the 
      prognosis of patients with DM and ACS treated with PCI via subsequent 
      implantation of Magmaris (Biotronik, Berlin, Germany)-a novel 
      magnesium-bioresorbable scaffold-is poorly investigated. METHODS: A total of 193 
      consecutive subjects with non-ST elevation acute coronary syndrome (NSTE-ACS) 
      who, from October 2016 to March 2020, received one or more Magmaris scaffolds 
      were enrolled in this study. The diabetic group was compared with non-diabetic 
      subjects. RESULTS: There were no significant differences in the occurrence of 
      primary endpoints (cardiovascular death, myocardial infarction, and in-stent 
      thrombosis) and principal secondary endpoints (target-lesion failure, scaffold 
      restenosis, death from any reason, and other cardiovascular events) between the 
      two compared groups in a 1-year follow-up period. CONCLUSIONS: The early 
      1-year-outcome of magnesium bioresorbable scaffold (Magmaris) seems to be 
      favorable and suggests that this novel BRS is safe and effective in subjects with 
      NSTE-ACS and co-existing DM.
FAU - Wlodarczak, Adrian
AU  - Wlodarczak A
AUID- ORCID: 0000-0003-3104-7728
AD  - Department of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland.
FAU - Lanocha, Magdalena
AU  - Lanocha M
AD  - Adalbert's Hospital, 61-144 Poznan, Poland.
FAU - Szudrowicz, Marek
AU  - Szudrowicz M
AD  - Department of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland.
FAU - Barycki, Mateusz
AU  - Barycki M
AD  - Department of Cardiology, Provincial Specialized Hospital in Legnica, 
      Iwaszkiewicza Str. 5, 59-220 Legnica, Poland.
FAU - Gosiewska, Alicja
AU  - Gosiewska A
AUID- ORCID: 0000-0001-6563-5742
AD  - Faculty of Mathematics and Information Science, Warsaw University of Technology, 
      00-662 Warsaw, Poland.
FAU - Kulczycki, Jan Jakub
AU  - Kulczycki JJ
AUID- ORCID: 0000-0002-6670-6044
AD  - Department of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland.
FAU - Lesiak, Maciej
AU  - Lesiak M
AUID- ORCID: 0000-0003-2630-5016
AD  - 1st Department of Cardiology, Poznan University of Medical Sciences, 61-491 
      Poznan, Poland.
FAU - Doroszko, Adrian
AU  - Doroszko A
AUID- ORCID: 0000-0001-5472-028X
AD  - Department of Internal Medicine, Hypertension and Clinical Oncology, Wroclaw 
      Medical University, 50-556 Wroclaw, Poland.
FAU - Rola, Piotr
AU  - Rola P
AUID- ORCID: 0000-0002-0963-2712
AD  - Department of Cardiology, Provincial Specialized Hospital in Legnica, 
      Iwaszkiewicza Str. 5, 59-220 Legnica, Poland.
LA  - eng
PT  - Journal Article
DEP - 20210718
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC8304146
OTO - NOTNLM
OT  - Magmaris
OT  - acute coronary syndrome (ACS)
OT  - coronary artery disease (CAD)
OT  - diabetes mellitus (DM)
OT  - magnesium bioresorbable scaffold (BRS)
OT  - percutaneous coronary intervention (PCI)
COIS- The authors declare no conflict of interest.
EDAT- 2021/07/25 06:00
MHDA- 2021/07/25 06:01
PMCR- 2021/07/18
CRDT- 2021/07/24 01:07
PHST- 2021/07/12 00:00 [received]
PHST- 2021/07/16 00:00 [accepted]
PHST- 2021/07/24 01:07 [entrez]
PHST- 2021/07/25 06:00 [pubmed]
PHST- 2021/07/25 06:01 [medline]
PHST- 2021/07/18 00:00 [pmc-release]
AID - jcm10143166 [pii]
AID - jcm-10-03166 [pii]
AID - 10.3390/jcm10143166 [doi]
PST - epublish
SO  - J Clin Med. 2021 Jul 18;10(14):3166. doi: 10.3390/jcm10143166.